Affinity Data by PubMed id=1731937

PubMed code 1731937

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92984 (L-Norvaline) Show SMILES CCC[C@H](N)C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	3.10E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92985 (2-Aminobutyrate) Show SMILES CCC([NH3+])C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92999 (Homoserine phosphate) Show SMILES N[C@@H](CCOP(O)(O)=O)C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	6.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92986 (L-Alanosine) Show SMILES N[C@@H](CN(O)N=O)C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	7.50E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM93000 (DL-2-Amino-5-phosphonovalerate) Show SMILES NC(CCCP(O)(O)=O)C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	8.40E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92987 (2,4-Diaminobutanoate) Show SMILES NCC[C@H](N)C(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92988 (D-aspartate alpha-benzyl ester) Show SMILES N[C@@H](CC([O-])=O)C(=O)OCc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	1.10E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM93001 (O-phospho-L-serine) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	1.20E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92989 (D-aspartate-beta-hydroxamate) Show SMILES N[C@@H](CC(=O)NO)C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	1.60E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92990 (Aminomalonate) Show SMILES NC(C([O-])=O)C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	2.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92992 (L-glutamate gamma-methyl ester) Show SMILES COC(=O)CC[C@H](N)C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	2.40E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92991 (L-norleucine) Show SMILES CCCC[C@H](N)C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	2.40E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92993 (DL-Isoserine) Show SMILES NCC(O)C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	3.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92994 (L-Valine) Show SMILES CC(C)[C@H](N)C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	3.20E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.80E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92995 (D-asparagine) Show SMILES N[C@H](CC(N)=O)C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	3.90E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92996 (3-Aminoglutarate) Show SMILES NC(CC(O)=O)CC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem	Article PubMed	4.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM93002 (DL-2-amino-4-phosphonobutyrate) Show SMILES NC(CCP(O)(O)=O)C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	6.10E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92997 (L-Aspartic dimethyl ester) Show SMILES COC(=O)C[C@H](N)C(=O)OC Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	7.10E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Escherichia coli)	BDBM92998 (L-alanine) Show SMILES C[C@H](N)C([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	9.90E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron					Assay Description Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...				Biochemistry 31: 799-805 (1992) Article DOI: 10.1021/bi00118a023 BindingDB Entry DOI: 10.7270/Q2GX4966
University of Akron					More data for this Ligand-Target Pair

* indicates data uncertainty>20%