Found 40 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206833
((2R)-ethyl 4-((3,5-bis(trifluoromethyl)phenyl)(2-m...)Show SMILES CCOC(=O)N1[C@H](CC)CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10| Show InChI InChI=1S/C25H23F9N6O2/c1-4-17-12-39(19-11-14(23(26,27)28)6-7-18(19)40(17)22(41)42-5-2)20(21-35-37-38(3)36-21)13-8-15(24(29,30)31)10-16(9-13)25(32,33)34/h6-11,17,20H,4-5,12H2,1-3H3/t17-,20?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206833
((2R)-ethyl 4-((3,5-bis(trifluoromethyl)phenyl)(2-m...)Show SMILES CCOC(=O)N1[C@H](CC)CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10| Show InChI InChI=1S/C25H23F9N6O2/c1-4-17-12-39(19-11-14(23(26,27)28)6-7-18(19)40(17)22(41)42-5-2)20(21-35-37-38(3)36-21)13-8-15(24(29,30)31)10-16(9-13)25(32,33)34/h6-11,17,20H,4-5,12H2,1-3H3/t17-,20?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206852
(CHEMBL394725 | isobutyl 4-((3,5-bis(trifluoromethy...)Show SMILES CCC1CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc2N1C(=O)OCC(C)C)C(F)(F)F |w:5.4,2.1| Show InChI InChI=1S/C27H27F9N6O2/c1-5-19-12-41(21-11-16(25(28,29)30)6-7-20(21)42(19)24(43)44-13-14(2)3)22(23-37-39-40(4)38-23)15-8-17(26(31,32)33)10-18(9-15)27(34,35)36/h6-11,14,19,22H,5,12-13H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 232 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206836
(CHEMBL241089 | ethyl 4-(1-(3,5-bis(trifluoromethyl...)Show SMILES CCOC(=O)N1C(CC)CN(C(C(=O)OC)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C25H23F9N2O4/c1-4-17-12-35(19-11-14(23(26,27)28)6-7-18(19)36(17)22(38)40-5-2)20(21(37)39-3)13-8-15(24(29,30)31)10-16(9-13)25(32,33)34/h6-11,17,20H,4-5,12H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206836
(CHEMBL241089 | ethyl 4-(1-(3,5-bis(trifluoromethyl...)Show SMILES CCOC(=O)N1C(CC)CN(C(C(=O)OC)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C25H23F9N2O4/c1-4-17-12-35(19-11-14(23(26,27)28)6-7-18(19)36(17)22(38)40-5-2)20(21(37)39-3)13-8-15(24(29,30)31)10-16(9-13)25(32,33)34/h6-11,17,20H,4-5,12H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206854
(4-((3,5-bis(trifluoromethyl)phenyl)(2-methyl-2H-te...)Show SMILES CCC1CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc2N1CC1CCCC1)C(F)(F)F |w:5.4,2.1| Show InChI InChI=1S/C28H29F9N6/c1-3-21-15-43(23-13-18(26(29,30)31)8-9-22(23)42(21)14-16-6-4-5-7-16)24(25-38-40-41(2)39-25)17-10-19(27(32,33)34)12-20(11-17)28(35,36)37/h8-13,16,21,24H,3-7,14-15H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 854 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206835
(CHEMBL394293 | ethyl 4-((3,5-bis(trifluoromethyl)p...)Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C25H23F9N6O2/c1-4-17-12-39(19-11-14(23(26,27)28)6-7-18(19)40(17)22(41)42-5-2)20(21-35-37-38(3)36-21)13-8-15(24(29,30)31)10-16(9-13)25(32,33)34/h6-11,17,20H,4-5,12H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 870 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206835
(CHEMBL394293 | ethyl 4-((3,5-bis(trifluoromethyl)p...)Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C25H23F9N6O2/c1-4-17-12-39(19-11-14(23(26,27)28)6-7-18(19)40(17)22(41)42-5-2)20(21-35-37-38(3)36-21)13-8-15(24(29,30)31)10-16(9-13)25(32,33)34/h6-11,17,20H,4-5,12H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 870 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206847
(CHEMBL238932 | butyl 4-((3,5-bis(trifluoromethyl)p...)Show SMILES CCCCOC(=O)N1C(CC)CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:13.12,8.8| Show InChI InChI=1S/C27H27F9N6O2/c1-4-6-9-44-24(43)42-19(5-2)14-41(21-13-16(25(28,29)30)7-8-20(21)42)22(23-37-39-40(3)38-23)15-10-17(26(31,32)33)12-18(11-15)27(34,35)36/h7-8,10-13,19,22H,4-6,9,14H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206856
((2S)-ethyl 4-((3,5-bis(trifluoromethyl)phenyl)(2-m...)Show SMILES CCOC(=O)N1[C@@H](CC)CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10| Show InChI InChI=1S/C25H23F9N6O2/c1-4-17-12-39(19-11-14(23(26,27)28)6-7-18(19)40(17)22(41)42-5-2)20(21-35-37-38(3)36-21)13-8-15(24(29,30)31)10-16(9-13)25(32,33)34/h6-11,17,20H,4-5,12H2,1-3H3/t17-,20?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206856
((2S)-ethyl 4-((3,5-bis(trifluoromethyl)phenyl)(2-m...)Show SMILES CCOC(=O)N1[C@@H](CC)CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10| Show InChI InChI=1S/C25H23F9N6O2/c1-4-17-12-39(19-11-14(23(26,27)28)6-7-18(19)40(17)22(41)42-5-2)20(21-35-37-38(3)36-21)13-8-15(24(29,30)31)10-16(9-13)25(32,33)34/h6-11,17,20H,4-5,12H2,1-3H3/t17-,20?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206843
(CHEMBL240675 | ethyl 4-(1-(3,5-bis(trifluoromethyl...)Show SMILES CCOC(=O)N1C(CC)CN(C(C(=O)OC)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(Br)ccc12 |w:11.10,6.6| Show InChI InChI=1S/C24H23BrF6N2O4/c1-4-17-12-32(19-11-16(25)6-7-18(19)33(17)22(35)37-5-2)20(21(34)36-3)13-8-14(23(26,27)28)10-15(9-13)24(29,30)31/h6-11,17,20H,4-5,12H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206832
(CHEMBL394995 | ethyl 4-((3,5-bis(trifluoromethyl)p...)Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(CCO)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C26H25F9N6O3/c1-3-18-13-39(20-12-15(24(27,28)29)5-6-19(20)41(18)23(43)44-4-2)21(22-36-38-40(37-22)7-8-42)14-9-16(25(30,31)32)11-17(10-14)26(33,34)35/h5-6,9-12,18,21,42H,3-4,7-8,13H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206832
(CHEMBL394995 | ethyl 4-((3,5-bis(trifluoromethyl)p...)Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(CCO)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C26H25F9N6O3/c1-3-18-13-39(20-12-15(24(27,28)29)5-6-19(20)41(18)23(43)44-4-2)21(22-36-38-40(37-22)7-8-42)14-9-16(25(30,31)32)11-17(10-14)26(33,34)35/h5-6,9-12,18,21,42H,3-4,7-8,13H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206839
(2-((1r,4r)-4-((4-((3,5-bis(trifluoromethyl)phenyl)...)Show SMILES CCC1CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc2N1C[C@H]1CC[C@H](CC(O)=O)CC1)C(F)(F)F |w:5.4,2.1,wU:37.41,wD:34.37,(15.92,-9.74,;14.58,-10.51,;13.24,-9.74,;13.23,-8.21,;11.9,-7.44,;11.89,-5.9,;10.55,-5.13,;9.14,-5.76,;8.11,-4.61,;8.87,-3.27,;8.24,-1.87,;10.38,-3.59,;13.22,-5.12,;14.54,-5.9,;15.83,-5.14,;15.83,-3.65,;14.51,-2.88,;13.21,-3.64,;14.5,-1.31,;14.5,.24,;12.91,-1.32,;16,-1.3,;17.21,-5.93,;18.55,-6.7,;18,-4.55,;16.47,-7.23,;10.57,-8.22,;9.23,-7.45,;7.9,-8.23,;7.91,-9.77,;9.23,-10.53,;10.56,-9.76,;11.91,-10.52,;11.92,-12.07,;10.58,-12.84,;9.24,-12.08,;7.92,-12.85,;7.93,-14.38,;6.58,-15.17,;5.24,-14.4,;5.23,-12.84,;3.91,-15.17,;9.26,-15.15,;10.58,-14.38,;6.56,-7.47,;5.22,-6.7,;7.32,-6.13,;5.79,-8.81,)| Show InChI InChI=1S/C31H33F9N6O2/c1-3-23-16-46(27(28-41-43-44(2)42-28)19-11-21(30(35,36)37)13-22(12-19)31(38,39)40)25-14-20(29(32,33)34)8-9-24(25)45(23)15-18-6-4-17(5-7-18)10-26(47)48/h8-9,11-14,17-18,23,27H,3-7,10,15-16H2,1-2H3,(H,47,48)/t17-,18-,23?,27? | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206853
(CHEMBL397062 | ethyl 4-((3,5-bis(trifluoromethyl)p...)Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(CCC#N)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C27H24F9N7O2/c1-3-19-14-41(21-13-16(25(28,29)30)6-7-20(21)43(19)24(44)45-4-2)22(23-38-40-42(39-23)9-5-8-37)15-10-17(26(31,32)33)12-18(11-15)27(34,35)36/h6-7,10-13,19,22H,3-5,9,14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206834
(CHEMBL395619 | benzyl 4-((3,5-bis(trifluoromethyl)...)Show SMILES CCC1CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc2N1C(=O)OCc1ccccc1)C(F)(F)F |w:5.4,2.1| Show InChI InChI=1S/C30H25F9N6O2/c1-3-22-15-44(25(26-40-42-43(2)41-26)18-11-20(29(34,35)36)13-21(12-18)30(37,38)39)24-14-19(28(31,32)33)9-10-23(24)45(22)27(46)47-16-17-7-5-4-6-8-17/h4-14,22,25H,3,15-16H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206840
(CHEMBL413002 | ethyl 4-((3,5-bis(trifluoromethyl)p...)Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(CCC(=O)OC)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C28H27F9N6O4/c1-4-19-14-41(21-13-16(26(29,30)31)6-7-20(21)43(19)25(45)47-5-2)23(24-38-40-42(39-24)9-8-22(44)46-3)15-10-17(27(32,33)34)12-18(11-15)28(35,36)37/h6-7,10-13,19,23H,4-5,8-9,14H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206829
(CHEMBL395365 | ethyl 4-((3,5-bis(trifluoromethyl)p...)Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(CC3CC3)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C28H27F9N6O2/c1-3-20-14-41(22-12-17(26(29,30)31)7-8-21(22)43(20)25(44)45-4-2)23(24-38-40-42(39-24)13-15-5-6-15)16-9-18(27(32,33)34)11-19(10-16)28(35,36)37/h7-12,15,20,23H,3-6,13-14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206844
(4-((3,5-bis(trifluoromethyl)phenyl)(2-methyl-2H-te...)Show SMILES CCC1CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc2N1C(=O)NCCO)C(F)(F)F |w:5.4,2.1| Show InChI InChI=1S/C25H24F9N7O2/c1-3-17-12-40(19-11-14(23(26,27)28)4-5-18(19)41(17)22(43)35-6-7-42)20(21-36-38-39(2)37-21)13-8-15(24(29,30)31)10-16(9-13)25(32,33)34/h4-5,8-11,17,20,42H,3,6-7,12H2,1-2H3,(H,35,43) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206844
(4-((3,5-bis(trifluoromethyl)phenyl)(2-methyl-2H-te...)Show SMILES CCC1CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc2N1C(=O)NCCO)C(F)(F)F |w:5.4,2.1| Show InChI InChI=1S/C25H24F9N7O2/c1-3-17-12-40(19-11-14(23(26,27)28)4-5-18(19)41(17)22(43)35-6-7-42)20(21-36-38-39(2)37-21)13-8-15(24(29,30)31)10-16(9-13)25(32,33)34/h4-5,8-11,17,20,42H,3,6-7,12H2,1-2H3,(H,35,43) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206838
(4-((3,5-bis(trifluoromethyl)phenyl)(2-methyl-2H-te...)Show SMILES CCC1CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc2N1CC1CCCCC1)C(F)(F)F |w:5.4,2.1| Show InChI InChI=1S/C29H31F9N6/c1-3-22-16-44(24-14-19(27(30,31)32)9-10-23(24)43(22)15-17-7-5-4-6-8-17)25(26-39-41-42(2)40-26)18-11-20(28(33,34)35)13-21(12-18)29(36,37)38/h9-14,17,22,25H,3-8,15-16H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206838
(4-((3,5-bis(trifluoromethyl)phenyl)(2-methyl-2H-te...)Show SMILES CCC1CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc2N1CC1CCCCC1)C(F)(F)F |w:5.4,2.1| Show InChI InChI=1S/C29H31F9N6/c1-3-22-16-44(24-14-19(27(30,31)32)9-10-23(24)43(22)15-17-7-5-4-6-8-17)25(26-39-41-42(2)40-26)18-11-20(28(33,34)35)13-21(12-18)29(36,37)38/h9-14,17,22,25H,3-8,15-16H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206845
(CHEMBL397058 | ethyl 4-((3,5-bis(trifluoromethyl)p...)Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(CCN(C)C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C28H30F9N7O2/c1-5-20-15-42(22-14-17(26(29,30)31)7-8-21(22)44(20)25(45)46-6-2)23(24-38-40-43(39-24)10-9-41(3)4)16-11-18(27(32,33)34)13-19(12-16)28(35,36)37/h7-8,11-14,20,23H,5-6,9-10,15H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206831
(CHEMBL241261 | ethyl 4-(1-(3,5-bis(trifluoromethyl...)Show SMILES CCOC(=O)N1C(CC)CN(C(C(=O)OC)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2ccccc12 |w:11.10,6.6| Show InChI InChI=1S/C24H24F6N2O4/c1-4-17-13-31(18-8-6-7-9-19(18)32(17)22(34)36-5-2)20(21(33)35-3)14-10-15(23(25,26)27)12-16(11-14)24(28,29)30/h6-12,17,20H,4-5,13H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206831
(CHEMBL241261 | ethyl 4-(1-(3,5-bis(trifluoromethyl...)Show SMILES CCOC(=O)N1C(CC)CN(C(C(=O)OC)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2ccccc12 |w:11.10,6.6| Show InChI InChI=1S/C24H24F6N2O4/c1-4-17-13-31(18-8-6-7-9-19(18)32(17)22(34)36-5-2)20(21(33)35-3)14-10-15(23(25,26)27)12-16(11-14)24(28,29)30/h6-12,17,20H,4-5,13H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206850
(CHEMBL394994 | ethyl 4-((3,5-bis(trifluoromethyl)p...)Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(CC(=O)OC(C)(C)C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C30H31F9N6O4/c1-6-20-14-43(22-13-17(28(31,32)33)8-9-21(22)45(20)26(47)48-7-2)24(25-40-42-44(41-25)15-23(46)49-27(3,4)5)16-10-18(29(34,35)36)12-19(11-16)30(37,38)39/h8-13,20,24H,6-7,14-15H2,1-5H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206855
(CHEMBL398073 | ethyl 4-((3,5-bis(trifluoromethyl)p...)Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(CC(=O)OC)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C27H25F9N6O4/c1-4-18-12-40(20-11-15(25(28,29)30)6-7-19(20)42(18)24(44)46-5-2)22(23-37-39-41(38-23)13-21(43)45-3)14-8-16(26(31,32)33)10-17(9-14)27(34,35)36/h6-11,18,22H,4-5,12-13H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206842
((4-((3,5-bis(trifluoromethyl)phenyl)(2-methyl-2H-t...)Show SMILES CCC1CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc2N1C(=O)N1CCOCC1)C(F)(F)F |w:5.4,2.1| Show InChI InChI=1S/C27H26F9N7O2/c1-3-19-14-42(21-13-16(25(28,29)30)4-5-20(21)43(19)24(44)41-6-8-45-9-7-41)22(23-37-39-40(2)38-23)15-10-17(26(31,32)33)12-18(11-15)27(34,35)36/h4-5,10-13,19,22H,3,6-9,14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206841
(4-((3,5-bis(trifluoromethyl)phenyl)(2-methyl-2H-te...)Show SMILES CCNC(=O)N1C(CC)CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C25H24F9N7O/c1-4-17-12-40(19-11-14(23(26,27)28)6-7-18(19)41(17)22(42)35-5-2)20(21-36-38-39(3)37-21)13-8-15(24(29,30)31)10-16(9-13)25(32,33)34/h6-11,17,20H,4-5,12H2,1-3H3,(H,35,42) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206851
(2-(5-((3,5-bis(trifluoromethyl)phenyl)(4-(ethoxyca...)Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(CC(O)=O)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C26H23F9N6O4/c1-3-17-11-39(19-10-14(24(27,28)29)5-6-18(19)41(17)23(44)45-4-2)21(22-36-38-40(37-22)12-20(42)43)13-7-15(25(30,31)32)9-16(8-13)26(33,34)35/h5-10,17,21H,3-4,11-12H2,1-2H3,(H,42,43) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206848
(2-ethylhexyl 4-((3,5-bis(trifluoromethyl)phenyl)(2...)Show SMILES CCCCC(CC)COC(=O)N1C(CC)CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:17.16,12.12,4.6| Show InChI InChI=1S/C31H35F9N6O2/c1-5-8-9-18(6-2)17-48-28(47)46-23(7-3)16-45(25-15-20(29(32,33)34)10-11-24(25)46)26(27-41-43-44(4)42-27)19-12-21(30(35,36)37)14-22(13-19)31(38,39)40/h10-15,18,23,26H,5-9,16-17H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206846
(CHEMBL241088 | ethyl 4-(1-(3,5-bis(trifluoromethyl...)Show SMILES CCOC(=O)N1C(CC)CN(C(C(=O)OC)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(Cl)c(Cl)cc12 |w:11.10,6.6| Show InChI InChI=1S/C24H22Cl2F6N2O4/c1-4-15-11-33(18-9-16(25)17(26)10-19(18)34(15)22(36)38-5-2)20(21(35)37-3)12-6-13(23(27,28)29)8-14(7-12)24(30,31)32/h6-10,15,20H,4-5,11H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206846
(CHEMBL241088 | ethyl 4-(1-(3,5-bis(trifluoromethyl...)Show SMILES CCOC(=O)N1C(CC)CN(C(C(=O)OC)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(Cl)c(Cl)cc12 |w:11.10,6.6| Show InChI InChI=1S/C24H22Cl2F6N2O4/c1-4-15-11-33(18-9-16(25)17(26)10-19(18)34(15)22(36)38-5-2)20(21(35)37-3)12-6-13(23(27,28)29)8-14(7-12)24(30,31)32/h6-10,15,20H,4-5,11H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206827
(CHEMBL240857 | ethyl 2-ethyl-4-(1-methoxy-1-oxo-3-...)Show SMILES CCOC(=O)N1C(CC)CN(C(Cc2ccccc2)C(=O)OC)c2ccccc12 |w:6.6,11.11| Show InChI InChI=1S/C23H28N2O4/c1-4-18-16-24(21(22(26)28-3)15-17-11-7-6-8-12-17)19-13-9-10-14-20(19)25(18)23(27)29-5-2/h6-14,18,21H,4-5,15-16H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206828
(CHEMBL441143 | ethyl 4-((3,5-bis(trifluoromethyl)p...)Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(CC(N)=O)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C26H24F9N7O3/c1-3-17-11-40(19-10-14(24(27,28)29)5-6-18(19)42(17)23(44)45-4-2)21(22-37-39-41(38-22)12-20(36)43)13-7-15(25(30,31)32)9-16(8-13)26(33,34)35/h5-10,17,21H,3-4,11-12H2,1-2H3,(H2,36,43) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206849
(4-((3,5-bis(trifluoromethyl)phenyl)(2-methyl-2H-te...)Show SMILES CCC1CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc2N1C(=O)N(C)C)C(F)(F)F |w:5.4,2.1| Show InChI InChI=1S/C25H24F9N7O/c1-5-17-12-40(19-11-14(23(26,27)28)6-7-18(19)41(17)22(42)38(2)3)20(21-35-37-39(4)36-21)13-8-15(24(29,30)31)10-16(9-13)25(32,33)34/h6-11,17,20H,5,12H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206828
(CHEMBL441143 | ethyl 4-((3,5-bis(trifluoromethyl)p...)Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(CC(N)=O)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C26H24F9N7O3/c1-3-17-11-40(19-10-14(24(27,28)29)5-6-18(19)42(17)23(44)45-4-2)21(22-37-39-41(38-22)12-20(36)43)13-7-15(25(30,31)32)9-16(8-13)26(33,34)35/h5-10,17,21H,3-4,11-12H2,1-2H3,(H2,36,43) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206830
(CHEMBL398577 | ethyl 4-(3-(3,5-bis(trifluoromethyl...)Show SMILES CCOC(=O)N1C(CC)CN(C(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)OC)c2ccccc12 |w:6.6,11.11| Show InChI InChI=1S/C25H26F6N2O4/c1-4-18-14-32(19-8-6-7-9-20(19)33(18)23(35)37-5-2)21(22(34)36-3)12-15-10-16(24(26,27)28)13-17(11-15)25(29,30)31/h6-11,13,18,21H,4-5,12,14H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50206837
((4-((3,5-bis(trifluoromethyl)phenyl)(2-methyl-2H-t...)Show SMILES CCC1CN(C(c2nnn(C)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc2N1C(=O)N1CCCC1)C(F)(F)F |w:5.4,2.1| Show InChI InChI=1S/C27H26F9N7O/c1-3-19-14-42(21-13-16(25(28,29)30)6-7-20(21)43(19)24(44)41-8-4-5-9-41)22(23-37-39-40(2)38-23)15-10-17(26(31,32)33)12-18(11-15)27(34,35)36/h6-7,10-13,19,22H,3-5,8-9,14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Array BioPharma
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma |
Bioorg Med Chem Lett 17: 2608-13 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.112
BindingDB Entry DOI: 10.7270/Q2ZG6RXM |
More data for this
Ligand-Target Pair | |
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