Found 24 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260268
(CHEMBL501261 | rPKPfQwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)CCCN=C(N)N)C(N)=O |r,wU:91.97,75.80,55.65,41.56,82.94,30.40,16.28,64.77,8.12,wD:98.106,4.4,(32.88,-5.76,;32.94,-4.22,;34.29,-3.5,;31.62,-3.41,;31.68,-1.87,;30.37,-1.06,;29.01,-1.78,;28.96,-3.32,;27.71,-.97,;27.76,.56,;29.12,1.29,;29.17,2.83,;30.43,.48,;26.35,-1.69,;25.04,-.88,;25.1,.66,;23.69,-1.6,;23.63,-3.15,;24.94,-3.96,;26.37,-3.38,;27.35,-4.56,;26.54,-5.87,;26.96,-7.34,;25.9,-8.45,;24.4,-8.08,;23.97,-6.6,;25.05,-5.49,;22.38,-.79,;21.02,-1.51,;20.96,-3.05,;19.71,-.7,;19.76,.84,;21.12,1.56,;22.43,.75,;23.78,1.47,;23.84,3.02,;22.53,3.83,;21.17,3.11,;18.35,-1.43,;17.04,-.62,;17.09,.93,;15.68,-1.35,;15.63,-2.87,;16.93,-3.7,;18.37,-3.12,;19.35,-4.3,;18.54,-5.61,;18.97,-7.08,;17.9,-8.18,;16.4,-7.82,;15.97,-6.33,;17.04,-5.23,;14.38,-.52,;13,-1.22,;12.96,-2.76,;11.71,-.4,;11.75,1.13,;13.11,1.86,;13.16,3.4,;11.88,4.19,;14.52,4.12,;10.36,-1.15,;9.06,-.33,;9.1,1.22,;7.7,-1.05,;7.65,-2.58,;8.95,-3.4,;10.31,-2.68,;11.61,-3.49,;11.56,-5.03,;10.21,-5.76,;8.9,-4.94,;6.39,-.23,;5.03,-.95,;4.99,-2.49,;3.73,-.14,;3.87,1.41,;2.24,1.8,;1.35,.37,;2.44,-.91,;2.19,-2.43,;3.32,-3.48,;.73,-2.89,;-.6,-2.09,;-1.94,-2.83,;-3.26,-2.04,;-4.61,-2.78,;-5.93,-1.99,;.76,-4.43,;2.1,-5.19,;3.43,-4.4,;2.12,-6.72,;.73,-7.44,;1.29,-9.03,;2.96,-8.99,;3.46,-7.39,;4.8,-6.61,;4.78,-5.08,;6.14,-7.36,;7.47,-6.6,;6.16,-8.91,;7.48,-9.68,;7.48,-11.23,;8.8,-12.02,;8.78,-13.56,;7.44,-14.33,;10.1,-14.35,;33.03,-1.15,;34.35,-1.96,;33.09,.39,)| Show InChI InChI=1S/C79H109N19O12/c1-46(2)38-59(68(83)100)91-70(102)60(39-47(3)4)92-73(105)64(43-51-45-88-56-28-14-12-25-53(51)56)95-72(104)61(40-48-20-7-5-8-21-48)93-74(106)63(42-50-44-87-55-27-13-11-24-52(50)55)94-69(101)57(32-33-67(82)99)89-71(103)62(41-49-22-9-6-10-23-49)96-76(108)66-31-19-37-98(66)78(110)58(29-15-16-34-80)90-75(107)65-30-18-36-97(65)77(109)54(81)26-17-35-86-79(84)85/h5-14,20-25,27-28,44-47,54,57-66,87-88H,15-19,26,29-43,80-81H2,1-4H3,(H2,82,99)(H2,83,100)(H,89,103)(H,90,107)(H,91,102)(H,92,105)(H,93,106)(H,94,101)(H,95,104)(H,96,108)(H4,84,85,86)/t54-,57+,58+,59+,60+,61+,62-,63-,64-,65+,66+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Displacement of [35S]MK677 from human ghrelin receptor expressed in african green monkey COS7 cells |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260271
(CHEMBL500703 | RwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCN=C(N)N)C(N)=O |r,wU:30.40,16.28,55.60,8.12,41.56,wD:4.4,(13.77,-48.69,;13.77,-47.15,;15.1,-46.38,;12.44,-46.38,;12.44,-44.84,;11.1,-44.08,;9.77,-44.85,;9.77,-46.39,;8.44,-44.08,;8.43,-42.54,;9.77,-41.77,;9.77,-40.23,;11.1,-42.54,;7.1,-44.85,;5.76,-44.09,;5.76,-42.55,;4.42,-44.86,;4.43,-46.4,;5.76,-47.16,;7.17,-46.53,;8.2,-47.68,;7.43,-49.01,;7.9,-50.48,;6.88,-51.62,;5.37,-51.3,;4.9,-49.84,;5.93,-48.69,;3.09,-44.08,;1.76,-44.85,;1.76,-46.39,;.43,-44.08,;.43,-42.55,;1.76,-41.77,;3.09,-42.54,;4.43,-41.77,;4.42,-40.23,;3.08,-39.47,;1.75,-40.24,;-.9,-44.85,;-2.24,-44.09,;-2.24,-42.56,;-3.57,-44.86,;-3.57,-46.4,;-2.24,-47.17,;-.84,-46.55,;.2,-47.69,;-.57,-49.02,;-.09,-50.48,;-1.13,-51.63,;-2.62,-51.31,;-3.1,-49.84,;-2.08,-48.7,;-4.9,-44.09,;-6.24,-44.86,;-6.24,-46.4,;-7.58,-44.09,;-8.89,-44.86,;-7.58,-42.55,;-6.24,-41.78,;-6.24,-40.24,;-4.91,-39.47,;-4.91,-37.93,;-6.23,-37.16,;-3.57,-37.15,;13.77,-44.07,;15.1,-44.85,;13.76,-42.53,)| Show InChI InChI=1S/C49H66N12O6/c1-28(2)21-38(43(51)62)57-45(64)39(22-29(3)4)59-48(67)42(25-32-27-56-37-19-11-9-16-34(32)37)61-46(65)40(23-30-13-6-5-7-14-30)60-47(66)41(24-31-26-55-36-18-10-8-15-33(31)36)58-44(63)35(50)17-12-20-54-49(52)53/h5-11,13-16,18-19,26-29,35,38-42,55-56H,12,17,20-25,50H2,1-4H3,(H2,51,62)(H,57,64)(H,58,63)(H,59,67)(H,60,66)(H,61,65)(H4,52,53,54)/t35-,38-,39-,40-,41+,42+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Displacement of [35S]MK677 from human ghrelin receptor expressed in african green monkey COS7 cells |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260270
(CHEMBL506986 | KwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCCN)C(N)=O |r| Show InChI InChI=1S/C49H66N10O6/c1-29(2)22-39(44(52)60)55-46(62)40(23-30(3)4)57-49(65)43(26-33-28-54-38-20-11-9-17-35(33)38)59-47(63)41(24-31-14-6-5-7-15-31)58-48(64)42(56-45(61)36(51)18-12-13-21-50)25-32-27-53-37-19-10-8-16-34(32)37/h5-11,14-17,19-20,27-30,36,39-43,53-54H,12-13,18,21-26,50-51H2,1-4H3,(H2,52,60)(H,55,62)(H,56,61)(H,57,65)(H,58,64)(H,59,63)/t36-,39-,40-,41-,42+,43+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Displacement of [35S]MK677 from human ghrelin receptor expressed in african green monkey COS7 cells |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260275
(AwFwLL-NH2 | CHEMBL509976)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)N)C(N)=O |r| Show InChI InChI=1S/C46H59N9O6/c1-26(2)19-36(41(48)56)51-43(58)37(20-27(3)4)53-46(61)40(23-31-25-50-35-18-12-10-16-33(31)35)55-44(59)38(21-29-13-7-6-8-14-29)54-45(60)39(52-42(57)28(5)47)22-30-24-49-34-17-11-9-15-32(30)34/h6-18,24-28,36-40,49-50H,19-23,47H2,1-5H3,(H2,48,56)(H,51,58)(H,52,57)(H,53,61)(H,54,60)(H,55,59)/t28-,36-,37-,38-,39+,40+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Agonist activity at human wild type ghrelin receptor expressed in african green monkey COS7 cells assessed as stimulation of constitutively stimulate... |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260275
(AwFwLL-NH2 | CHEMBL509976)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)N)C(N)=O |r| Show InChI InChI=1S/C46H59N9O6/c1-26(2)19-36(41(48)56)51-43(58)37(20-27(3)4)53-46(61)40(23-31-25-50-35-18-12-10-16-33(31)35)55-44(59)38(21-29-13-7-6-8-14-29)54-45(60)39(52-42(57)28(5)47)22-30-24-49-34-17-11-9-15-32(30)34/h6-18,24-28,36-40,49-50H,19-23,47H2,1-5H3,(H2,48,56)(H,51,58)(H,52,57)(H,53,61)(H,54,60)(H,55,59)/t28-,36-,37-,38-,39+,40+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human ghrelin receptor expressed in african green monkey COS7 cells assessed as constitutively stimulated inositol phosph... |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260268
(CHEMBL501261 | rPKPfQwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)CCCN=C(N)N)C(N)=O |r,wU:91.97,75.80,55.65,41.56,82.94,30.40,16.28,64.77,8.12,wD:98.106,4.4,(32.88,-5.76,;32.94,-4.22,;34.29,-3.5,;31.62,-3.41,;31.68,-1.87,;30.37,-1.06,;29.01,-1.78,;28.96,-3.32,;27.71,-.97,;27.76,.56,;29.12,1.29,;29.17,2.83,;30.43,.48,;26.35,-1.69,;25.04,-.88,;25.1,.66,;23.69,-1.6,;23.63,-3.15,;24.94,-3.96,;26.37,-3.38,;27.35,-4.56,;26.54,-5.87,;26.96,-7.34,;25.9,-8.45,;24.4,-8.08,;23.97,-6.6,;25.05,-5.49,;22.38,-.79,;21.02,-1.51,;20.96,-3.05,;19.71,-.7,;19.76,.84,;21.12,1.56,;22.43,.75,;23.78,1.47,;23.84,3.02,;22.53,3.83,;21.17,3.11,;18.35,-1.43,;17.04,-.62,;17.09,.93,;15.68,-1.35,;15.63,-2.87,;16.93,-3.7,;18.37,-3.12,;19.35,-4.3,;18.54,-5.61,;18.97,-7.08,;17.9,-8.18,;16.4,-7.82,;15.97,-6.33,;17.04,-5.23,;14.38,-.52,;13,-1.22,;12.96,-2.76,;11.71,-.4,;11.75,1.13,;13.11,1.86,;13.16,3.4,;11.88,4.19,;14.52,4.12,;10.36,-1.15,;9.06,-.33,;9.1,1.22,;7.7,-1.05,;7.65,-2.58,;8.95,-3.4,;10.31,-2.68,;11.61,-3.49,;11.56,-5.03,;10.21,-5.76,;8.9,-4.94,;6.39,-.23,;5.03,-.95,;4.99,-2.49,;3.73,-.14,;3.87,1.41,;2.24,1.8,;1.35,.37,;2.44,-.91,;2.19,-2.43,;3.32,-3.48,;.73,-2.89,;-.6,-2.09,;-1.94,-2.83,;-3.26,-2.04,;-4.61,-2.78,;-5.93,-1.99,;.76,-4.43,;2.1,-5.19,;3.43,-4.4,;2.12,-6.72,;.73,-7.44,;1.29,-9.03,;2.96,-8.99,;3.46,-7.39,;4.8,-6.61,;4.78,-5.08,;6.14,-7.36,;7.47,-6.6,;6.16,-8.91,;7.48,-9.68,;7.48,-11.23,;8.8,-12.02,;8.78,-13.56,;7.44,-14.33,;10.1,-14.35,;33.03,-1.15,;34.35,-1.96,;33.09,.39,)| Show InChI InChI=1S/C79H109N19O12/c1-46(2)38-59(68(83)100)91-70(102)60(39-47(3)4)92-73(105)64(43-51-45-88-56-28-14-12-25-53(51)56)95-72(104)61(40-48-20-7-5-8-21-48)93-74(106)63(42-50-44-87-55-27-13-11-24-52(50)55)94-69(101)57(32-33-67(82)99)89-71(103)62(41-49-22-9-6-10-23-49)96-76(108)66-31-19-37-98(66)78(110)58(29-15-16-34-80)90-75(107)65-30-18-36-97(65)77(109)54(81)26-17-35-86-79(84)85/h5-14,20-25,27-28,44-47,54,57-66,87-88H,15-19,26,29-43,80-81H2,1-4H3,(H2,82,99)(H2,83,100)(H,89,103)(H,90,107)(H,91,102)(H,92,105)(H,93,106)(H,94,101)(H,95,104)(H,96,108)(H4,84,85,86)/t54-,57+,58+,59+,60+,61+,62-,63-,64-,65+,66+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human ghrelin receptor expressed in african green monkey COS7 cells assessed as constitutively stimulated inositol phosph... |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260271
(CHEMBL500703 | RwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCN=C(N)N)C(N)=O |r,wU:30.40,16.28,55.60,8.12,41.56,wD:4.4,(13.77,-48.69,;13.77,-47.15,;15.1,-46.38,;12.44,-46.38,;12.44,-44.84,;11.1,-44.08,;9.77,-44.85,;9.77,-46.39,;8.44,-44.08,;8.43,-42.54,;9.77,-41.77,;9.77,-40.23,;11.1,-42.54,;7.1,-44.85,;5.76,-44.09,;5.76,-42.55,;4.42,-44.86,;4.43,-46.4,;5.76,-47.16,;7.17,-46.53,;8.2,-47.68,;7.43,-49.01,;7.9,-50.48,;6.88,-51.62,;5.37,-51.3,;4.9,-49.84,;5.93,-48.69,;3.09,-44.08,;1.76,-44.85,;1.76,-46.39,;.43,-44.08,;.43,-42.55,;1.76,-41.77,;3.09,-42.54,;4.43,-41.77,;4.42,-40.23,;3.08,-39.47,;1.75,-40.24,;-.9,-44.85,;-2.24,-44.09,;-2.24,-42.56,;-3.57,-44.86,;-3.57,-46.4,;-2.24,-47.17,;-.84,-46.55,;.2,-47.69,;-.57,-49.02,;-.09,-50.48,;-1.13,-51.63,;-2.62,-51.31,;-3.1,-49.84,;-2.08,-48.7,;-4.9,-44.09,;-6.24,-44.86,;-6.24,-46.4,;-7.58,-44.09,;-8.89,-44.86,;-7.58,-42.55,;-6.24,-41.78,;-6.24,-40.24,;-4.91,-39.47,;-4.91,-37.93,;-6.23,-37.16,;-3.57,-37.15,;13.77,-44.07,;15.1,-44.85,;13.76,-42.53,)| Show InChI InChI=1S/C49H66N12O6/c1-28(2)21-38(43(51)62)57-45(64)39(22-29(3)4)59-48(67)42(25-32-27-56-37-19-11-9-16-34(32)37)61-46(65)40(23-30-13-6-5-7-14-30)60-47(66)41(24-31-26-55-36-18-10-8-15-33(31)36)58-44(63)35(50)17-12-20-54-49(52)53/h5-11,13-16,18-19,26-29,35,38-42,55-56H,12,17,20-25,50H2,1-4H3,(H2,51,62)(H,57,64)(H,58,63)(H,59,67)(H,60,66)(H,61,65)(H4,52,53,54)/t35-,38-,39-,40-,41+,42+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human ghrelin receptor expressed in african green monkey COS7 cells assessed as constitutively stimulated inositol phosph... |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260270
(CHEMBL506986 | KwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCCN)C(N)=O |r| Show InChI InChI=1S/C49H66N10O6/c1-29(2)22-39(44(52)60)55-46(62)40(23-30(3)4)57-49(65)43(26-33-28-54-38-20-11-9-17-35(33)38)59-47(63)41(24-31-14-6-5-7-15-31)58-48(64)42(56-45(61)36(51)18-12-13-21-50)25-32-27-53-37-19-10-8-16-34(32)37/h5-11,14-17,19-20,27-30,36,39-43,53-54H,12-13,18,21-26,50-51H2,1-4H3,(H2,52,60)(H,55,62)(H,56,61)(H,57,65)(H,58,64)(H,59,63)/t36-,39-,40-,41-,42+,43+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human wild type ghrelin receptor expressed in african green monkey COS7 cells assessed as inhibition of constitutively st... |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260270
(CHEMBL506986 | KwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCCN)C(N)=O |r| Show InChI InChI=1S/C49H66N10O6/c1-29(2)22-39(44(52)60)55-46(62)40(23-30(3)4)57-49(65)43(26-33-28-54-38-20-11-9-17-35(33)38)59-47(63)41(24-31-14-6-5-7-15-31)58-48(64)42(56-45(61)36(51)18-12-13-21-50)25-32-27-53-37-19-10-8-16-34(32)37/h5-11,14-17,19-20,27-30,36,39-43,53-54H,12-13,18,21-26,50-51H2,1-4H3,(H2,52,60)(H,55,62)(H,56,61)(H,57,65)(H,58,64)(H,59,63)/t36-,39-,40-,41-,42+,43+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human ghrelin receptor expressed in african green monkey COS7 cells assessed as constitutively stimulated inositol phosph... |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260275
(AwFwLL-NH2 | CHEMBL509976)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)N)C(N)=O |r| Show InChI InChI=1S/C46H59N9O6/c1-26(2)19-36(41(48)56)51-43(58)37(20-27(3)4)53-46(61)40(23-31-25-50-35-18-12-10-16-33(31)35)55-44(59)38(21-29-13-7-6-8-14-29)54-45(60)39(52-42(57)28(5)47)22-30-24-49-34-17-11-9-15-32(30)34/h6-18,24-28,36-40,49-50H,19-23,47H2,1-5H3,(H2,48,56)(H,51,58)(H,52,57)(H,53,61)(H,54,60)(H,55,59)/t28-,36-,37-,38-,39+,40+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Displacement of [35S]MK677 from human ghrelin receptor expressed in african green monkey COS7 cells |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260272
(CHEMBL502208 | HwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(N)=O |r| Show InChI InChI=1S/C49H61N11O6/c1-28(2)18-39(44(51)61)56-46(63)40(19-29(3)4)58-49(66)43(22-32-25-54-38-17-11-9-15-35(32)38)60-47(64)41(20-30-12-6-5-7-13-30)59-48(65)42(21-31-24-53-37-16-10-8-14-34(31)37)57-45(62)36(50)23-33-26-52-27-55-33/h5-17,24-29,36,39-43,53-54H,18-23,50H2,1-4H3,(H2,51,61)(H,52,55)(H,56,63)(H,57,62)(H,58,66)(H,59,65)(H,60,64)/t36-,39-,40-,41-,42+,43+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Displacement of [35S]MK677 from human ghrelin receptor expressed in african green monkey COS7 cells |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260274
(CHEMBL449590 | DwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CC(O)=O)C(N)=O |r| Show InChI InChI=1S/C47H59N9O8/c1-26(2)18-36(42(49)59)52-44(61)37(19-27(3)4)54-47(64)40(22-30-25-51-35-17-11-9-15-32(30)35)56-45(62)38(20-28-12-6-5-7-13-28)55-46(63)39(53-43(60)33(48)23-41(57)58)21-29-24-50-34-16-10-8-14-31(29)34/h5-17,24-27,33,36-40,50-51H,18-23,48H2,1-4H3,(H2,49,59)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H,56,62)(H,57,58)/t33-,36-,37-,38-,39+,40+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Displacement of [35S]MK677 from human ghrelin receptor expressed in african green monkey COS7 cells |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260272
(CHEMBL502208 | HwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(N)=O |r| Show InChI InChI=1S/C49H61N11O6/c1-28(2)18-39(44(51)61)56-46(63)40(19-29(3)4)58-49(66)43(22-32-25-54-38-17-11-9-15-35(32)38)60-47(64)41(20-30-12-6-5-7-13-30)59-48(65)42(21-31-24-53-37-16-10-8-14-34(31)37)57-45(62)36(50)23-33-26-52-27-55-33/h5-17,24-29,36,39-43,53-54H,18-23,50H2,1-4H3,(H2,51,61)(H,52,55)(H,56,63)(H,57,62)(H,58,66)(H,59,65)(H,60,64)/t36-,39-,40-,41-,42+,43+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human ghrelin receptor expressed in african green monkey COS7 cells assessed as constitutively stimulated inositol phosph... |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260273
(CHEMBL507636 | DprwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@H]1CCCN1C(=O)[C@@H](N)CC(O)=O)C(N)=O |r,wU:66.70,41.56,30.40,16.28,73.79,8.12,wD:55.67,4.4,(17.4,-13.08,;17.4,-11.54,;18.72,-10.77,;16.07,-10.78,;16.05,-9.24,;14.72,-8.47,;14.71,-6.93,;16.04,-6.16,;13.37,-6.17,;13.36,-4.63,;14.69,-3.86,;14.69,-2.32,;16.04,-4.62,;12.04,-6.94,;10.71,-6.18,;10.69,-4.64,;9.38,-6.95,;9.39,-8.49,;10.72,-9.25,;12.12,-8.63,;13.15,-9.77,;12.39,-11.1,;12.87,-12.57,;11.85,-13.72,;10.34,-13.4,;9.86,-11.94,;10.89,-10.79,;8.04,-6.19,;6.71,-6.97,;6.71,-8.51,;5.37,-6.2,;5.36,-4.67,;6.69,-3.89,;8.03,-4.65,;9.36,-3.88,;9.35,-2.34,;8.02,-1.58,;6.69,-2.35,;4.04,-6.98,;2.7,-6.23,;2.69,-4.69,;1.37,-7,;1.38,-8.54,;2.71,-9.3,;4.12,-8.67,;5.15,-9.82,;4.38,-11.15,;4.87,-12.62,;3.84,-13.76,;2.33,-13.45,;1.85,-11.98,;2.88,-10.84,;.04,-6.23,;-1.29,-7,;-1.28,-8.55,;-2.63,-6.24,;-2.64,-4.7,;-1.31,-3.92,;-1.31,-2.39,;.02,-1.61,;.01,-.07,;-1.32,.7,;1.35,.71,;-3.96,-7.01,;-5.29,-6.25,;-5.31,-4.71,;-6.63,-7.02,;-7.53,-8.29,;-9.03,-7.52,;-8.76,-5.86,;-7.07,-5.61,;-6.08,-3.87,;-4.52,-3.86,;-6.94,-2.62,;-8.43,-2.61,;-6.19,-1.21,;-4.65,-1.2,;-3.89,.14,;-3.87,-2.53,;17.38,-8.46,;17.37,-6.93,;18.72,-9.22,)| Show InChI InChI=1S/C58H78N14O10/c1-32(2)24-43(50(60)75)67-52(77)44(25-33(3)4)68-54(79)47(28-36-31-65-41-19-11-9-17-38(36)41)71-53(78)45(26-34-14-6-5-7-15-34)69-55(80)46(27-35-30-64-40-18-10-8-16-37(35)40)70-51(76)42(20-12-22-63-58(61)62)66-56(81)48-21-13-23-72(48)57(82)39(59)29-49(73)74/h5-11,14-19,30-33,39,42-48,64-65H,12-13,20-29,59H2,1-4H3,(H2,60,75)(H,66,81)(H,67,77)(H,68,79)(H,69,80)(H,70,76)(H,71,78)(H,73,74)(H4,61,62,63)/t39-,42+,43-,44-,45-,46+,47+,48+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human ghrelin receptor expressed in african green monkey COS7 cells assessed as constitutively stimulated inositol phosph... |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260276
(CHEMBL499371 | QwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCC(N)=O)C(N)=O |r| Show InChI InChI=1S/C48H62N10O7/c1-27(2)20-37(43(51)60)54-45(62)38(21-28(3)4)56-48(65)41(24-31-26-53-36-17-11-9-15-33(31)36)58-46(63)39(22-29-12-6-5-7-13-29)57-47(64)40(55-44(61)34(49)18-19-42(50)59)23-30-25-52-35-16-10-8-14-32(30)35/h5-17,25-28,34,37-41,52-53H,18-24,49H2,1-4H3,(H2,50,59)(H2,51,60)(H,54,62)(H,55,61)(H,56,65)(H,57,64)(H,58,63)/t34-,37-,38-,39-,40+,41+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Displacement of [35S]MK677 from human ghrelin receptor expressed in african green monkey COS7 cells |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260278
(CHEMBL444131 | wFwGG-NH2)Show SMILES N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NCC(N)=O |r| Show InChI InChI=1S/C35H38N8O5/c36-26(15-22-17-38-27-12-6-4-10-24(22)27)33(46)42-29(14-21-8-2-1-3-9-21)35(48)43-30(34(47)41-20-32(45)40-19-31(37)44)16-23-18-39-28-13-7-5-11-25(23)28/h1-13,17-18,26,29-30,38-39H,14-16,19-20,36H2,(H2,37,44)(H,40,45)(H,41,47)(H,42,46)(H,43,48)/t26-,29+,30-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 159 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human ghrelin receptor expressed in african green monkey COS7 cells assessed as constitutively stimulated inositol phosph... |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260273
(CHEMBL507636 | DprwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@H]1CCCN1C(=O)[C@@H](N)CC(O)=O)C(N)=O |r,wU:66.70,41.56,30.40,16.28,73.79,8.12,wD:55.67,4.4,(17.4,-13.08,;17.4,-11.54,;18.72,-10.77,;16.07,-10.78,;16.05,-9.24,;14.72,-8.47,;14.71,-6.93,;16.04,-6.16,;13.37,-6.17,;13.36,-4.63,;14.69,-3.86,;14.69,-2.32,;16.04,-4.62,;12.04,-6.94,;10.71,-6.18,;10.69,-4.64,;9.38,-6.95,;9.39,-8.49,;10.72,-9.25,;12.12,-8.63,;13.15,-9.77,;12.39,-11.1,;12.87,-12.57,;11.85,-13.72,;10.34,-13.4,;9.86,-11.94,;10.89,-10.79,;8.04,-6.19,;6.71,-6.97,;6.71,-8.51,;5.37,-6.2,;5.36,-4.67,;6.69,-3.89,;8.03,-4.65,;9.36,-3.88,;9.35,-2.34,;8.02,-1.58,;6.69,-2.35,;4.04,-6.98,;2.7,-6.23,;2.69,-4.69,;1.37,-7,;1.38,-8.54,;2.71,-9.3,;4.12,-8.67,;5.15,-9.82,;4.38,-11.15,;4.87,-12.62,;3.84,-13.76,;2.33,-13.45,;1.85,-11.98,;2.88,-10.84,;.04,-6.23,;-1.29,-7,;-1.28,-8.55,;-2.63,-6.24,;-2.64,-4.7,;-1.31,-3.92,;-1.31,-2.39,;.02,-1.61,;.01,-.07,;-1.32,.7,;1.35,.71,;-3.96,-7.01,;-5.29,-6.25,;-5.31,-4.71,;-6.63,-7.02,;-7.53,-8.29,;-9.03,-7.52,;-8.76,-5.86,;-7.07,-5.61,;-6.08,-3.87,;-4.52,-3.86,;-6.94,-2.62,;-8.43,-2.61,;-6.19,-1.21,;-4.65,-1.2,;-3.89,.14,;-3.87,-2.53,;17.38,-8.46,;17.37,-6.93,;18.72,-9.22,)| Show InChI InChI=1S/C58H78N14O10/c1-32(2)24-43(50(60)75)67-52(77)44(25-33(3)4)68-54(79)47(28-36-31-65-41-19-11-9-17-38(36)41)71-53(78)45(26-34-14-6-5-7-15-34)69-55(80)46(27-35-30-64-40-18-10-8-16-37(35)40)70-51(76)42(20-12-22-63-58(61)62)66-56(81)48-21-13-23-72(48)57(82)39(59)29-49(73)74/h5-11,14-19,30-33,39,42-48,64-65H,12-13,20-29,59H2,1-4H3,(H2,60,75)(H,66,81)(H,67,77)(H,68,79)(H,69,80)(H,70,76)(H,71,78)(H,73,74)(H4,61,62,63)/t39-,42+,43-,44-,45-,46+,47+,48+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Displacement of [35S]MK677 from human ghrelin receptor expressed in african green monkey COS7 cells |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260274
(CHEMBL449590 | DwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CC(O)=O)C(N)=O |r| Show InChI InChI=1S/C47H59N9O8/c1-26(2)18-36(42(49)59)52-44(61)37(19-27(3)4)54-47(64)40(22-30-25-51-35-17-11-9-15-32(30)35)56-45(62)38(20-28-12-6-5-7-13-28)55-46(63)39(53-43(60)33(48)23-41(57)58)21-29-24-50-34-16-10-8-14-31(29)34/h5-17,24-27,33,36-40,50-51H,18-23,48H2,1-4H3,(H2,49,59)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H,56,62)(H,57,58)/t33-,36-,37-,38-,39+,40+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human ghrelin receptor expressed in african green monkey COS7 cells assessed as constitutively stimulated inositol phosph... |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260269
(CHEMBL450217 | wFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](N)Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C43H54N8O5/c1-25(2)18-35(39(45)52)48-41(54)36(19-26(3)4)50-43(56)38(22-29-24-47-34-17-11-9-15-31(29)34)51-42(55)37(20-27-12-6-5-7-13-27)49-40(53)32(44)21-28-23-46-33-16-10-8-14-30(28)33/h5-17,23-26,32,35-38,46-47H,18-22,44H2,1-4H3,(H2,45,52)(H,48,54)(H,49,53)(H,50,56)(H,51,55)/t32-,35+,36+,37+,38-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Displacement of [35S]MK677 from human ghrelin receptor expressed in african green monkey COS7 cells |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260278
(CHEMBL444131 | wFwGG-NH2)Show SMILES N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NCC(N)=O |r| Show InChI InChI=1S/C35H38N8O5/c36-26(15-22-17-38-27-12-6-4-10-24(22)27)33(46)42-29(14-21-8-2-1-3-9-21)35(48)43-30(34(47)41-20-32(45)40-19-31(37)44)16-23-18-39-28-13-7-5-11-25(23)28/h1-13,17-18,26,29-30,38-39H,14-16,19-20,36H2,(H2,37,44)(H,40,45)(H,41,47)(H,42,46)(H,43,48)/t26-,29+,30-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Displacement of [35S]MK677 from human ghrelin receptor expressed in african green monkey COS7 cells |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260276
(CHEMBL499371 | QwFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCC(N)=O)C(N)=O |r| Show InChI InChI=1S/C48H62N10O7/c1-27(2)20-37(43(51)60)54-45(62)38(21-28(3)4)56-48(65)41(24-31-26-53-36-17-11-9-15-33(31)36)58-46(63)39(22-29-12-6-5-7-13-29)57-47(64)40(55-44(61)34(49)18-19-42(50)59)23-30-25-52-35-16-10-8-14-32(30)35/h5-17,25-28,34,37-41,52-53H,18-24,49H2,1-4H3,(H2,50,59)(H2,51,60)(H,54,62)(H,55,61)(H,56,65)(H,57,64)(H,58,63)/t34-,37-,38-,39-,40+,41+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human ghrelin receptor expressed in african green monkey COS7 cells assessed as constitutively stimulated inositol phosph... |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260277
(CHEMBL447444 | wFwAA-NH2)Show SMILES C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](N)Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C37H42N8O5/c1-21(33(39)46)42-34(47)22(2)43-36(49)32(18-25-20-41-30-15-9-7-13-27(25)30)45-37(50)31(16-23-10-4-3-5-11-23)44-35(48)28(38)17-24-19-40-29-14-8-6-12-26(24)29/h3-15,19-22,28,31-32,40-41H,16-18,38H2,1-2H3,(H2,39,46)(H,42,47)(H,43,49)(H,44,48)(H,45,50)/t21-,22-,28+,31-,32+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Displacement of [35S]MK677 from human ghrelin receptor expressed in african green monkey COS7 cells |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260269
(CHEMBL450217 | wFwLL-NH2)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](N)Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C43H54N8O5/c1-25(2)18-35(39(45)52)48-41(54)36(19-26(3)4)50-43(56)38(22-29-24-47-34-17-11-9-15-31(29)34)51-42(55)37(20-27-12-6-5-7-13-27)49-40(53)32(44)21-28-23-46-33-16-10-8-14-30(28)33/h5-17,23-26,32,35-38,46-47H,18-22,44H2,1-4H3,(H2,45,52)(H,48,54)(H,49,53)(H,50,56)(H,51,55)/t32-,35+,36+,37+,38-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human ghrelin receptor expressed in african green monkey COS7 cells assessed as constitutively stimulated inositol phosph... |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50260277
(CHEMBL447444 | wFwAA-NH2)Show SMILES C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](N)Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C37H42N8O5/c1-21(33(39)46)42-34(47)22(2)43-36(49)32(18-25-20-41-30-15-9-7-13-27(25)30)45-37(50)31(16-23-10-4-3-5-11-23)44-35(48)28(38)17-24-19-40-29-14-8-6-12-26(24)29/h3-15,19-22,28,31-32,40-41H,16-18,38H2,1-2H3,(H2,39,46)(H,42,47)(H,43,49)(H,44,48)(H,45,50)/t21-,22-,28+,31-,32+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human ghrelin receptor expressed in african green monkey COS7 cells assessed as constitutively stimulated inositol phosph... |
J Biol Chem 282: 15799-811 (2007)
Article DOI: 10.1074/jbc.M609796200
BindingDB Entry DOI: 10.7270/Q2251HZ3 |
More data for this
Ligand-Target Pair | |
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