Found 18 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476303
(CHEMBL227521)Show InChI InChI=1S/C19H20FNO2/c1-21-18-8-4-16(5-9-18)2-3-17-6-10-19(11-7-17)23-15-14-22-13-12-20/h4-11,21H,12-15H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476296
(CHEMBL228033)Show InChI InChI=1S/C15H13NO/c1-16-14-8-4-12(5-9-14)2-3-13-6-10-15(17)11-7-13/h4-11,16-17H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476293
(CHEMBL227495)Show InChI InChI=1S/C21H24FNO3/c1-23-20-8-4-18(5-9-20)2-3-19-6-10-21(11-7-19)26-17-16-25-15-14-24-13-12-22/h4-11,23H,12-17H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476299
(CHEMBL228034)Show InChI InChI=1S/C15H12O2/c1-17-15-10-6-13(7-11-15)3-2-12-4-8-14(16)9-5-12/h4-11,16H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476287
(CHEMBL224096)Show InChI InChI=1S/C22H26FNO3/c1-24(2)21-9-5-19(6-10-21)3-4-20-7-11-22(12-8-20)27-18-17-26-16-15-25-14-13-23/h5-12H,13-18H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476298
(CHEMBL223285)Show InChI InChI=1S/C15H13NO/c1-17-15-10-6-13(7-11-15)3-2-12-4-8-14(16)9-5-12/h4-11H,16H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476292
(CHEMBL227577)Show InChI InChI=1S/C19H21NO3/c1-20-18-8-4-16(5-9-18)2-3-17-6-10-19(11-7-17)23-15-14-22-13-12-21/h4-11,20-21H,12-15H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476301
(CHEMBL413436)Show InChI InChI=1S/C22H27NO4/c1-23(2)21-9-5-19(6-10-21)3-4-20-7-11-22(12-8-20)27-18-17-26-16-15-25-14-13-24/h5-12,24H,13-18H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476300
(CHEMBL389671)Show InChI InChI=1S/C20H23NO3/c1-21(2)19-9-5-17(6-10-19)3-4-18-7-11-20(12-8-18)24-16-15-23-14-13-22/h5-12,22H,13-16H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476291
(CHEMBL227674)Show InChI InChI=1S/C21H25NO4/c1-22-20-8-4-18(5-9-20)2-3-19-6-10-21(11-7-19)26-17-16-25-15-14-24-13-12-23/h4-11,22-23H,12-17H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476297
(CHEMBL227576)Show InChI InChI=1S/C20H22FNO2/c1-22(2)19-9-5-17(6-10-19)3-4-18-7-11-20(12-8-18)24-16-15-23-14-13-21/h5-12H,13-16H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476288
(CHEMBL373663)Show InChI InChI=1S/C18H18FNO2/c19-11-12-21-13-14-22-18-9-5-16(6-10-18)2-1-15-3-7-17(20)8-4-15/h3-10H,11-14,20H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476302
(CHEMBL227751)Show InChI InChI=1S/C20H21FO4/c21-11-12-23-13-14-24-15-16-25-20-9-5-18(6-10-20)2-1-17-3-7-19(22)8-4-17/h3-10,22H,11-16H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476286
(CHEMBL226610)Show InChI InChI=1S/C20H22FNO3/c21-11-12-23-13-14-24-15-16-25-20-9-5-18(6-10-20)2-1-17-3-7-19(22)8-4-17/h3-10H,11-16,22H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476294
(CHEMBL227752)Show InChI InChI=1S/C20H23NO4/c21-19-7-3-17(4-8-19)1-2-18-5-9-20(10-6-18)25-16-15-24-14-13-23-12-11-22/h3-10,22H,11-16,21H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476290
(CHEMBL227625)Show InChI InChI=1S/C14H12N2/c15-13-7-3-11(4-8-13)1-2-12-5-9-14(16)10-6-12/h3-10H,15-16H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| 76 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476295
(CHEMBL373548)Show InChI InChI=1S/C14H11NO/c15-13-7-3-11(4-8-13)1-2-12-5-9-14(16)10-6-12/h3-10,16H,15H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 106 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50476289
(CHEBI:51579 | DIPHENYLACETYLENE)Show InChI InChI=1S/C14H10/c1-3-7-13(8-4-1)11-12-14-9-5-2-6-10-14/h1-10H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| 175 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates |
J Med Chem 50: 2415-23 (2007)
Article DOI: 10.1021/jm070090j BindingDB Entry DOI: 10.7270/Q2S46VS2 |
More data for this Ligand-Target Pair | |