Found 24 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211814
(4-(2-(4-fluorophenyl)-7-((isopropylamino)methyl)H-...)Show SMILES CC(C)NCc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N[C@@H](C)c2ccccc2)n1 Show InChI InChI=1S/C29H29FN6/c1-19(2)32-18-21-14-16-36-26(17-21)35-27(23-9-11-24(30)12-10-23)28(36)25-13-15-31-29(34-25)33-20(3)22-7-5-4-6-8-22/h4-17,19-20,32H,18H2,1-3H3,(H,31,33,34)/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211811
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(Nc2ccccc2)n1 Show InChI InChI=1S/C26H23FN6/c1-32(2)17-18-13-15-33-23(16-18)31-24(19-8-10-20(27)11-9-19)25(33)22-12-14-28-26(30-22)29-21-6-4-3-5-7-21/h3-16H,17H2,1-2H3,(H,28,29,30) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211805
(4-(7-(((3-(dimethylamino)propyl)(methyl)amino)meth...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CCCN(C)C)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C32H36FN7/c1-23(25-9-6-5-7-10-25)35-32-34-17-15-28(36-32)31-30(26-11-13-27(33)14-12-26)37-29-21-24(16-20-40(29)31)22-39(4)19-8-18-38(2)3/h5-7,9-17,20-21,23H,8,18-19,22H2,1-4H3,(H,34,35,36)/t23-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182359
(CHEMBL379059 | N-benzyl-4-(7-((dimethylamino)methy...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2ccccc2)n1 Show InChI InChI=1S/C27H25FN6/c1-33(2)18-20-13-15-34-24(16-20)32-25(21-8-10-22(28)11-9-21)26(34)23-12-14-29-27(31-23)30-17-19-6-4-3-5-7-19/h3-16H,17-18H2,1-2H3,(H,29,30,31) | UniProtKB/TrEMBL
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0810 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211820
(4-(7-(((2-(azetidin-1-yl)ethyl)(methyl)amino)methy...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CCN3CCC3)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C32H34FN7/c1-23(25-7-4-3-5-8-25)35-32-34-15-13-28(36-32)31-30(26-9-11-27(33)12-10-26)37-29-21-24(14-18-40(29)31)22-38(2)19-20-39-16-6-17-39/h3-5,7-15,18,21,23H,6,16-17,19-20,22H2,1-2H3,(H,34,35,36)/t23-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211802
(2-(((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethylami...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CCO)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C29H29FN6O/c1-20(22-6-4-3-5-7-22)32-29-31-14-12-25(33-29)28-27(23-8-10-24(30)11-9-23)34-26-18-21(13-15-36(26)28)19-35(2)16-17-37/h3-15,18,20,37H,16-17,19H2,1-2H3,(H,31,32,33)/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211812
(4-(2-(4-fluorophenyl)-7-((isopropyl(methyl)amino)m...)Show SMILES CC(C)N(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N[C@@H](C)c2ccccc2)n1 Show InChI InChI=1S/C30H31FN6/c1-20(2)36(4)19-22-15-17-37-27(18-22)35-28(24-10-12-25(31)13-11-24)29(37)26-14-16-32-30(34-26)33-21(3)23-8-6-5-7-9-23/h5-18,20-21H,19H2,1-4H3,(H,32,33,34)/t21-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211803
(4-(7-((ethyl(methyl)amino)methyl)-2-(4-fluoropheny...)Show SMILES CCN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N[C@@H](C)c2ccccc2)n1 Show InChI InChI=1S/C29H29FN6/c1-4-35(3)19-21-15-17-36-26(18-21)34-27(23-10-12-24(30)13-11-23)28(36)25-14-16-31-29(33-25)32-20(2)22-8-6-5-7-9-22/h5-18,20H,4,19H2,1-3H3,(H,31,32,33)/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211821
(2-(((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethylami...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)C(CO)CO)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C30H31FN6O2/c1-20(22-6-4-3-5-7-22)33-30-32-14-12-26(34-30)29-28(23-8-10-24(31)11-9-23)35-27-16-21(13-15-37(27)29)17-36(2)25(18-38)19-39/h3-16,20,25,38-39H,17-19H2,1-2H3,(H,32,33,34)/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211808
(CHEMBL233008 | N-(2-(((2-(4-fluorophenyl)-3-(2-((S...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CCNS(C)(=O)=O)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C30H32FN7O2S/c1-21(23-7-5-4-6-8-23)34-30-32-15-13-26(35-30)29-28(24-9-11-25(31)12-10-24)36-27-19-22(14-17-38(27)29)20-37(2)18-16-33-41(3,39)40/h4-15,17,19,21,33H,16,18,20H2,1-3H3,(H,32,34,35)/t21-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211819
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES CC(C)Nc1nccc(n1)-c1c(nc2cc(CN(C)C)ccn12)-c1ccc(F)cc1 Show InChI InChI=1S/C23H25FN6/c1-15(2)26-23-25-11-9-19(27-23)22-21(17-5-7-18(24)8-6-17)28-20-13-16(14-29(3)4)10-12-30(20)22/h5-13,15H,14H2,1-4H3,(H,25,26,27) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211816
((S)-2-(((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethy...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)[C@@H](C)C(=O)N(C)C)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C32H34FN7O/c1-21(24-9-7-6-8-10-24)35-32-34-17-15-27(36-32)30-29(25-11-13-26(33)14-12-25)37-28-19-23(16-18-40(28)30)20-39(5)22(2)31(41)38(3)4/h6-19,21-22H,20H2,1-5H3,(H,34,35,36)/t21-,22-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211810
(4-(2-(4-fluorophenyl)-7-((methyl((tetrahydrofuran-...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CC3CCCO3)ccn12)-c1ccc(F)cc1)c1ccccc1 |w:19.19| Show InChI InChI=1S/C32H33FN6O/c1-22(24-7-4-3-5-8-24)35-32-34-16-14-28(36-32)31-30(25-10-12-26(33)13-11-25)37-29-19-23(15-17-39(29)31)20-38(2)21-27-9-6-18-40-27/h3-5,7-8,10-17,19,22,27H,6,9,18,20-21H2,1-2H3,(H,34,35,36)/t22-,27?/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182361
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCC(C)(C)C)n1 Show InChI InChI=1S/C25H29FN6/c1-25(2,3)16-28-24-27-12-10-20(29-24)23-22(18-6-8-19(26)9-7-18)30-21-14-17(15-31(4)5)11-13-32(21)23/h6-14H,15-16H2,1-5H3,(H,27,28,29) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211823
(4-(7-((ethyl(methyl)amino)methyl)-2-(4-fluoropheny...)Show SMILES CCN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCC(C)(C)C)n1 Show InChI InChI=1S/C26H31FN6/c1-6-32(5)16-18-12-14-33-22(15-18)31-23(19-7-9-20(27)10-8-19)24(33)21-11-13-28-25(30-21)29-17-26(2,3)4/h7-15H,6,16-17H2,1-5H3,(H,28,29,30) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211818
(CHEMBL233011 | N-tert-butyl-4-(7-((dimethylamino)m...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NC(C)(C)C)n1 Show InChI InChI=1S/C24H27FN6/c1-24(2,3)29-23-26-12-10-19(27-23)22-21(17-6-8-18(25)9-7-17)28-20-14-16(15-30(4)5)11-13-31(20)22/h6-14H,15H2,1-5H3,(H,26,27,29) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211822
(2-(((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethylami...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CC(=O)N3CCCC3)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C33H34FN7O/c1-23(25-8-4-3-5-9-25)36-33-35-16-14-28(37-33)32-31(26-10-12-27(34)13-11-26)38-29-20-24(15-19-41(29)32)21-39(2)22-30(42)40-17-6-7-18-40/h3-5,8-16,19-20,23H,6-7,17-18,21-22H2,1-2H3,(H,35,36,37)/t23-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211817
(4-(7-(azetidin-1-ylmethyl)-2-(4-fluorophenyl)H-imi...)Show SMILES CC(C)(C)CNc1nccc(n1)-c1c(nc2cc(CN3CCC3)ccn12)-c1ccc(F)cc1 Show InChI InChI=1S/C26H29FN6/c1-26(2,3)17-29-25-28-11-9-21(30-25)24-23(19-5-7-20(27)8-6-19)31-22-15-18(10-14-33(22)24)16-32-12-4-13-32/h5-11,14-15H,4,12-13,16-17H2,1-3H3,(H,28,29,30) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211815
(1-(azetidin-1-yl)-2-(((2-(4-fluorophenyl)-3-(2-((S...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CC(=O)N3CCC3)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C32H32FN7O/c1-22(24-7-4-3-5-8-24)35-32-34-15-13-27(36-32)31-30(25-9-11-26(33)12-10-25)37-28-19-23(14-18-40(28)31)20-38(2)21-29(41)39-16-6-17-39/h3-5,7-15,18-19,22H,6,16-17,20-21H2,1-2H3,(H,34,35,36)/t22-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211806
(4-(2-(4-fluorophenyl)-7-((isopropyl(methyl)amino)m...)Show SMILES CC(C)N(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCC(C)(C)C)n1 Show InChI InChI=1S/C27H33FN6/c1-18(2)33(6)16-19-12-14-34-23(15-19)32-24(20-7-9-21(28)10-8-20)25(34)22-11-13-29-26(31-22)30-17-27(3,4)5/h7-15,18H,16-17H2,1-6H3,(H,29,30,31) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211809
(4-(7-(azetidin-1-ylmethyl)-2-(4-fluorophenyl)H-imi...)Show SMILES CC(C)Nc1nccc(n1)-c1c(nc2cc(CN3CCC3)ccn12)-c1ccc(F)cc1 Show InChI InChI=1S/C24H25FN6/c1-16(2)27-24-26-10-8-20(28-24)23-22(18-4-6-19(25)7-5-18)29-21-14-17(9-13-31(21)23)15-30-11-3-12-30/h4-10,13-14,16H,3,11-12,15H2,1-2H3,(H,26,27,28) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.860 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211807
(4-(2-(4-fluorophenyl)-7-((isopropyl(methyl)amino)m...)Show SMILES CC(C)Nc1nccc(n1)-c1c(nc2cc(CN(C)C(C)C)ccn12)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN6/c1-16(2)28-25-27-12-10-21(29-25)24-23(19-6-8-20(26)9-7-19)30-22-14-18(11-13-32(22)24)15-31(5)17(3)4/h6-14,16-17H,15H2,1-5H3,(H,27,28,29) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211813
(CHEMBL391937 | N-tert-butyl-4-(2-(4-fluorophenyl)-...)Show SMILES CC(C)N(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NC(C)(C)C)n1 Show InChI InChI=1S/C26H31FN6/c1-17(2)32(6)16-18-12-14-33-22(15-18)30-23(19-7-9-20(27)10-8-19)24(33)21-11-13-28-25(29-21)31-26(3,4)5/h7-15,17H,16H2,1-6H3,(H,28,29,31) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211804
(CHEMBL393256 | ethyl 4-((2-(4-fluorophenyl)-3-(2-(...)Show SMILES CCOC(=O)N1CCN(Cc2ccn3c(c(nc3c2)-c2ccc(F)cc2)-c2ccnc(N[C@@H](C)c3ccccc3)n2)CC1 Show InChI InChI=1S/C33H34FN7O2/c1-3-43-33(42)40-19-17-39(18-20-40)22-24-14-16-41-29(21-24)38-30(26-9-11-27(34)12-10-26)31(41)28-13-15-35-32(37-28)36-23(2)25-7-5-4-6-8-25/h4-16,21,23H,3,17-20,22H2,1-2H3,(H,35,36,37)/t23-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
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