Found 22 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Androgen receptor
(Homo sapiens (Human)) | BDBM50220643
(6-((cyclopropylmethyl)(propyl)amino)-4-(trifluorom...)Show InChI InChI=1S/C14H16F3N3/c1-2-5-20(9-10-3-4-10)13-6-12(14(15,16)17)11(7-18)8-19-13/h6,8,10H,2-5,9H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220635
(6-(butyl(methyl)amino)-4-(trifluoromethyl)nicotino...)Show InChI InChI=1S/C12H14F3N3/c1-3-4-5-18(2)11-6-10(12(13,14)15)9(7-16)8-17-11/h6,8H,3-5H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220642
(6-(sec-butyl(methyl)amino)-4-(trifluoromethyl)nico...)Show InChI InChI=1S/C12H14F3N3/c1-4-8(2)18(3)11-5-10(12(13,14)15)9(6-16)7-17-11/h5,7-8H,4H2,1-3H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM25428
(4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidaz...)Show SMILES CC1(C)N(CCCCO)C(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C17H18F3N3O3/c1-16(2)14(25)23(15(26)22(16)7-3-4-8-24)12-6-5-11(10-21)13(9-12)17(18,19)20/h5-6,9,24H,3-4,7-8H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 15.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM25432
(6-{methyl[(1R)-1-phenylethyl]amino}-4-(trifluorome...)Show SMILES C[C@@H](N(C)c1cc(c(cn1)C#N)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C16H14F3N3/c1-11(12-6-4-3-5-7-12)22(2)15-8-14(16(17,18)19)13(9-20)10-21-15/h3-8,10-11H,1-2H3/t11-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM25428
(4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidaz...)Show SMILES CC1(C)N(CCCCO)C(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C17H18F3N3O3/c1-16(2)14(25)23(15(26)22(16)7-3-4-8-24)12-6-5-11(10-21)13(9-12)17(18,19)20/h5-6,9,24H,3-4,7-8H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 31.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Antagonist activity at human androgen receptor expressed in MDA-MB-453 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM25432
(6-{methyl[(1R)-1-phenylethyl]amino}-4-(trifluorome...)Show SMILES C[C@@H](N(C)c1cc(c(cn1)C#N)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C16H14F3N3/c1-11(12-6-4-3-5-7-12)22(2)15-8-14(16(17,18)19)13(9-20)10-21-15/h3-8,10-11H,1-2H3/t11-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Antagonist activity at human androgen receptor expressed in MDA-MB-453 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220640
(6-(4-methylpiperidin-1-yl)-4-(trifluoromethyl)nico...)Show InChI InChI=1S/C13H14F3N3/c1-9-2-4-19(5-3-9)12-6-11(13(14,15)16)10(7-17)8-18-12/h6,8-9H,2-5H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220644
(6-(dipropylamino)-4-(trifluoromethyl)nicotinonitri...)Show InChI InChI=1S/C13H16F3N3/c1-3-5-19(6-4-2)12-7-11(13(14,15)16)10(8-17)9-18-12/h7,9H,3-6H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220639
(6-(methyl(1-phenylethyl)amino)-4-(trifluoromethyl)...)Show SMILES CC(N(C)c1cc(c(cn1)C#N)C(F)(F)F)c1ccccc1 |w:1.0| Show InChI InChI=1S/C16H14F3N3/c1-11(12-6-4-3-5-7-12)22(2)15-8-14(16(17,18)19)13(9-20)10-21-15/h3-8,10-11H,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 123 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220640
(6-(4-methylpiperidin-1-yl)-4-(trifluoromethyl)nico...)Show InChI InChI=1S/C13H14F3N3/c1-9-2-4-19(5-3-9)12-6-11(13(14,15)16)10(7-17)8-18-12/h6,8-9H,2-5H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Antagonist activity at human androgen receptor expressed in MDA-MB-453 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220638
(6-(octahydroisoquinolin-2(1H)-yl)-4-(trifluorometh...)Show SMILES FC(F)(F)c1cc(ncc1C#N)N1CCC2CCCCC2C1 |w:15.15,20.22| Show InChI InChI=1S/C16H18F3N3/c17-16(18,19)14-7-15(21-9-13(14)8-20)22-6-5-11-3-1-2-4-12(11)10-22/h7,9,11-12H,1-6,10H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 169 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220641
(6-(piperidin-1-yl)-4-(trifluoromethyl)nicotinonitr...)Show InChI InChI=1S/C12H12F3N3/c13-12(14,15)10-6-11(17-8-9(10)7-16)18-4-2-1-3-5-18/h6,8H,1-5H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 209 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220639
(6-(methyl(1-phenylethyl)amino)-4-(trifluoromethyl)...)Show SMILES CC(N(C)c1cc(c(cn1)C#N)C(F)(F)F)c1ccccc1 |w:1.0| Show InChI InChI=1S/C16H14F3N3/c1-11(12-6-4-3-5-7-12)22(2)15-8-14(16(17,18)19)13(9-20)10-21-15/h3-8,10-11H,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 229 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Antagonist activity at human androgen receptor expressed in MDA-MB-453 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220638
(6-(octahydroisoquinolin-2(1H)-yl)-4-(trifluorometh...)Show SMILES FC(F)(F)c1cc(ncc1C#N)N1CCC2CCCCC2C1 |w:15.15,20.22| Show InChI InChI=1S/C16H18F3N3/c17-16(18,19)14-7-15(21-9-13(14)8-20)22-6-5-11-3-1-2-4-12(11)10-22/h7,9,11-12H,1-6,10H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Antagonist activity at human androgen receptor expressed in MDA-MB-453 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220641
(6-(piperidin-1-yl)-4-(trifluoromethyl)nicotinonitr...)Show InChI InChI=1S/C12H12F3N3/c13-12(14,15)10-6-11(17-8-9(10)7-16)18-4-2-1-3-5-18/h6,8H,1-5H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 422 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Antagonist activity at human androgen receptor expressed in MDA-MB-453 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220642
(6-(sec-butyl(methyl)amino)-4-(trifluoromethyl)nico...)Show InChI InChI=1S/C12H14F3N3/c1-4-8(2)18(3)11-5-10(12(13,14)15)9(6-16)7-17-11/h5,7-8H,4H2,1-3H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Antagonist activity at human androgen receptor expressed in MDA-MB-453 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220635
(6-(butyl(methyl)amino)-4-(trifluoromethyl)nicotino...)Show InChI InChI=1S/C12H14F3N3/c1-3-4-5-18(2)11-6-10(12(13,14)15)9(7-16)8-17-11/h6,8H,3-5H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Antagonist activity at human androgen receptor expressed in MDA-MB-453 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220644
(6-(dipropylamino)-4-(trifluoromethyl)nicotinonitri...)Show InChI InChI=1S/C13H16F3N3/c1-3-5-19(6-4-2)12-7-11(13(14,15)16)10(8-17)9-18-12/h7,9H,3-6H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Antagonist activity at human androgen receptor expressed in MDA-MB-453 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220643
(6-((cyclopropylmethyl)(propyl)amino)-4-(trifluorom...)Show InChI InChI=1S/C14H16F3N3/c1-2-5-20(9-10-3-4-10)13-6-12(14(15,16)17)11(7-18)8-19-13/h6,8,10H,2-5,9H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Antagonist activity at human androgen receptor expressed in MDA-MB-453 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220637
((S)-6-(methyl(1-phenylethyl)amino)-4-(trifluoromet...)Show SMILES C[C@H](N(C)c1cc(c(cn1)C#N)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C16H14F3N3/c1-11(12-6-4-3-5-7-12)22(2)15-8-14(16(17,18)19)13(9-20)10-21-15/h3-8,10-11H,1-2H3/t11-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50220636
((R)-6-(1-phenylethylamino)-4-(trifluoromethyl)nico...)Show InChI InChI=1S/C15H12F3N3/c1-10(11-5-3-2-4-6-11)21-14-7-13(15(16,17)18)12(8-19)9-20-14/h2-7,9-10H,1H3,(H,20,21)/t10-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cells |
Bioorg Med Chem Lett 17: 5693-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.059
BindingDB Entry DOI: 10.7270/Q2GH9HPQ |
More data for this
Ligand-Target Pair | |
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