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PubMed code 18262416

Compile data set for download or QSAR
Found 28 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50197898
PNG
(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)
Show SMILES OC(=O)c1cccc(n1)C1=C(CCC1)c1cc(Cl)ccc1OCc1ccc(F)cc1F |t:10|
Show InChI InChI=1S/C24H18ClF2NO3/c25-15-8-10-23(31-13-14-7-9-16(26)12-20(14)27)19(11-15)17-3-1-4-18(17)21-5-2-6-22(28-21)24(29)30/h2,5-12H,1,3-4,13H2,(H,29,30)
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n/an/a 2.5n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423557
PNG
(CHEMBL403330)
Show SMILES CC(C)COc1ccc(Cl)cc1Cc1ccc(o1)C([O-])=O
Show InChI InChI=1S/C16H17ClO4/c1-10(2)9-20-14-5-3-12(17)7-11(14)8-13-4-6-15(21-13)16(18)19/h3-7,10H,8-9H2,1-2H3,(H,18,19)/p-1
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n/an/a 3.20n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423570
PNG
(CHEMBL209800)
Show SMILES CC(C)COc1ccc(Cl)cc1-c1ccc(C)n1-c1cccc(c1)C(O)=O
Show InChI InChI=1S/C22H22ClNO3/c1-14(2)13-27-21-10-8-17(23)12-19(21)20-9-7-15(3)24(20)18-6-4-5-16(11-18)22(25)26/h4-12,14H,13H2,1-3H3,(H,25,26)
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n/an/a 5n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423563
PNG
(CHEMBL272793)
Show SMILES [O-]C(=O)c1ccc(Cc2cc(Cl)ccc2OCc2ccccc2)o1
Show InChI InChI=1S/C19H15ClO4/c20-15-6-8-17(23-12-13-4-2-1-3-5-13)14(10-15)11-16-7-9-18(24-16)19(21)22/h1-10H,11-12H2,(H,21,22)/p-1
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n/an/a 6.30n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423574
PNG
(CHEMBL255652)
Show SMILES [O-]C(=O)c1csc(Cc2cc(Cl)ccc2OCc2ccccc2)n1
Show InChI InChI=1S/C18H14ClNO3S/c19-14-6-7-16(23-10-12-4-2-1-3-5-12)13(8-14)9-17-20-15(11-24-17)18(21)22/h1-8,11H,9-10H2,(H,21,22)/p-1
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n/an/a 6.30n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50191163
PNG
(1-(2-(benzyloxy)-5-bromobenzyl)-5-methyl-1H-pyrazo...)
Show SMILES Cc1cc(nn1Cc1cc(Br)ccc1OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C19H17BrN2O3/c1-13-9-17(19(23)24)21-22(13)11-15-10-16(20)7-8-18(15)25-12-14-5-3-2-4-6-14/h2-10H,11-12H2,1H3,(H,23,24)
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n/an/a 6.30n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50183185
PNG
(3-(2-(2-(benzyloxy)-5-chlorophenyl)-5-methyl-1H-py...)
Show SMILES Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(c1)C(O)=O
Show InChI InChI=1S/C25H20ClNO3/c1-17-10-12-23(27(17)21-9-5-8-19(14-21)25(28)29)22-15-20(26)11-13-24(22)30-16-18-6-3-2-4-7-18/h2-15H,16H2,1H3,(H,28,29)
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n/an/a 7.90n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423558
PNG
(CHEMBL255009)
Show SMILES CC(C)COc1ccc(Cl)cc1Cc1nc(cs1)C([O-])=O
Show InChI InChI=1S/C15H16ClNO3S/c1-9(2)7-20-13-4-3-11(16)5-10(13)6-14-17-12(8-21-14)15(18)19/h3-5,8-9H,6-7H2,1-2H3,(H,18,19)/p-1
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n/an/a 7.90n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50412226
PNG
(CHEMBL404525)
Show SMILES Cc1cc(nn1Cc1cc(Cl)ccc1OCc1ccccc1)C([O-])=O
Show InChI InChI=1S/C19H17ClN2O3/c1-13-9-17(19(23)24)21-22(13)11-15-10-16(20)7-8-18(15)25-12-14-5-3-2-4-6-14/h2-10H,11-12H2,1H3,(H,23,24)/p-1
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n/an/a 10n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423573
PNG
(CHEMBL407175)
Show SMILES Cc1cc(oc1Cc1cc(Cl)ccc1OCc1ccccc1)C([O-])=O
Show InChI InChI=1S/C20H17ClO4/c1-13-9-19(20(22)23)25-18(13)11-15-10-16(21)7-8-17(15)24-12-14-5-3-2-4-6-14/h2-10H,11-12H2,1H3,(H,22,23)/p-1
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n/an/a 10n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423571
PNG
(CHEMBL270208)
Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(cc1C)C([O-])=O
Show InChI InChI=1S/C16H19ClN2O3/c1-10(2)9-22-15-5-4-13(17)7-12(15)8-19-11(3)6-14(18-19)16(20)21/h4-7,10H,8-9H2,1-3H3,(H,20,21)/p-1
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n/an/a 10n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50183188
PNG
(3-(2-(2-(benzyloxy)-5-chlorophenyl)cyclopent-1-eny...)
Show SMILES OC(=O)c1cccc(c1)C1=C(CCC1)c1cc(Cl)ccc1OCc1ccccc1 |t:10|
Show InChI InChI=1S/C25H21ClO3/c26-20-12-13-24(29-16-17-6-2-1-3-7-17)23(15-20)22-11-5-10-21(22)18-8-4-9-19(14-18)25(27)28/h1-4,6-9,12-15H,5,10-11,16H2,(H,27,28)
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n/an/a 13n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423567
PNG
(CHEMBL257464)
Show SMILES [O-]C(=O)c1coc(Cc2cc(Cl)ccc2OCc2ccccc2)n1
Show InChI InChI=1S/C18H14ClNO4/c19-14-6-7-16(23-10-12-4-2-1-3-5-12)13(8-14)9-17-20-15(11-24-17)18(21)22/h1-8,11H,9-10H2,(H,21,22)/p-1
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n/an/a 20n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423555
PNG
(CHEMBL401768)
Show SMILES [O-]C(=O)c1csc(Nc2cc(Cl)ccc2OCc2ccccc2)n1
Show InChI InChI=1S/C17H13ClN2O3S/c18-12-6-7-15(23-9-11-4-2-1-3-5-11)13(8-12)19-17-20-14(10-24-17)16(21)22/h1-8,10H,9H2,(H,19,20)(H,21,22)/p-1
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n/an/a 25n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423566
PNG
(CHEMBL258057)
Show SMILES [O-]C(=O)c1nc(Cc2cc(Cl)ccc2OCc2ccccc2)cs1
Show InChI InChI=1S/C18H14ClNO3S/c19-14-6-7-16(23-10-12-4-2-1-3-5-12)13(8-14)9-15-11-24-17(20-15)18(21)22/h1-8,11H,9-10H2,(H,21,22)/p-1
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n/an/a 25n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423556
PNG
(CHEMBL403329)
Show SMILES CC(C)COc1ccc(Cl)cc1Cc1cccc(n1)C(O)=O
Show InChI InChI=1S/C17H18ClNO3/c1-11(2)10-22-16-7-6-13(18)8-12(16)9-14-4-3-5-15(19-14)17(20)21/h3-8,11H,9-10H2,1-2H3,(H,20,21)
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n/an/a 40n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423561
PNG
(CHEMBL256674)
Show SMILES [O-]C(=O)c1csc(Cc2cc(Cl)ccc2OCc2ccccc2)c1
Show InChI InChI=1S/C19H15ClO3S/c20-16-6-7-18(23-11-13-4-2-1-3-5-13)14(8-16)9-17-10-15(12-24-17)19(21)22/h1-8,10,12H,9,11H2,(H,21,22)/p-1
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n/an/a 40n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423562
PNG
(CHEMBL408367)
Show SMILES [O-]C(=O)c1ccc(Cc2cc(Cl)ccc2OCc2ccccc2)s1
Show InChI InChI=1S/C19H15ClO3S/c20-15-6-8-17(23-12-13-4-2-1-3-5-13)14(10-15)11-16-7-9-18(24-16)19(21)22/h1-10H,11-12H2,(H,21,22)/p-1
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n/an/a 50n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423553
PNG
(CHEMBL404760)
Show SMILES [O-]C(=O)Cc1csc(n1)-c1cc(Cl)ccc1OCc1ccccc1
Show InChI InChI=1S/C18H14ClNO3S/c19-13-6-7-16(23-10-12-4-2-1-3-5-12)15(8-13)18-20-14(11-24-18)9-17(21)22/h1-8,11H,9-10H2,(H,21,22)/p-1
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n/an/a 50n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423569
PNG
(CHEMBL403460)
Show SMILES [O-]C(=O)c1ccn(Cc2cc(Cl)ccc2OCc2ccccc2)n1
Show InChI InChI=1S/C18H15ClN2O3/c19-15-6-7-17(24-12-13-4-2-1-3-5-13)14(10-15)11-21-9-8-16(20-21)18(22)23/h1-10H,11-12H2,(H,22,23)/p-1
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n/an/a 79n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423572
PNG
(CHEMBL270174)
Show SMILES OC(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2)n1
Show InChI InChI=1S/C20H16ClNO3/c21-16-9-10-19(25-13-14-5-2-1-3-6-14)15(11-16)12-17-7-4-8-18(22-17)20(23)24/h1-11H,12-13H2,(H,23,24)
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n/an/a 158n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423568
PNG
(CHEMBL403459)
Show SMILES Cc1cc(cn1Cc1cc(Cl)ccc1OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C20H18ClNO3/c1-14-9-17(20(23)24)12-22(14)11-16-10-18(21)7-8-19(16)25-13-15-5-3-2-4-6-15/h2-10,12H,11,13H2,1H3,(H,23,24)
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n/an/a 158n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423564
PNG
(CHEMBL535640)
Show SMILES Cn1cc(nc1Cc1cc(Cl)ccc1OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C19H17ClN2O3/c1-22-11-16(19(23)24)21-18(22)10-14-9-15(20)7-8-17(14)25-12-13-5-3-2-4-6-13/h2-9,11H,10,12H2,1H3,(H,23,24)
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n/an/a 316n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423560
PNG
(CHEMBL404239)
Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2)c1
Show InChI InChI=1S/C21H17ClO3/c22-19-9-10-20(25-14-15-5-2-1-3-6-15)18(13-19)12-16-7-4-8-17(11-16)21(23)24/h1-11,13H,12,14H2,(H,23,24)/p-1
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n/an/a 316n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423554
PNG
(CHEMBL270162)
Show SMILES [O-]C(=O)c1csc(n1)-c1cc(Cl)ccc1OCc1ccccc1
Show InChI InChI=1S/C17H12ClNO3S/c18-12-6-7-15(22-9-11-4-2-1-3-5-11)13(8-12)16-19-14(10-23-16)17(20)21/h1-8,10H,9H2,(H,20,21)/p-1
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n/an/a 631n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423565
PNG
(CHEMBL257846)
Show SMILES [O-]C(=O)c1cnc(Cc2cc(Cl)ccc2OCc2ccccc2)s1
Show InChI InChI=1S/C18H14ClNO3S/c19-14-6-7-15(23-11-12-4-2-1-3-5-12)13(8-14)9-17-20-10-16(24-17)18(21)22/h1-8,10H,9,11H2,(H,21,22)/p-1
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n/an/a 631n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423559
PNG
(CHEMBL258303)
Show SMILES [O-]C(=O)c1cncc(Cc2cc(Cl)ccc2OCc2ccccc2)c1
Show InChI InChI=1S/C20H16ClNO3/c21-18-6-7-19(25-13-14-4-2-1-3-5-14)16(10-18)8-15-9-17(20(23)24)12-22-11-15/h1-7,9-12H,8,13H2,(H,23,24)/p-1
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n/an/a 631n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50423552
PNG
(CHEMBL273145)
Show SMILES OC(=O)c1cccc(Oc2cc(Cl)ccc2OCc2ccccc2)n1
Show InChI InChI=1S/C19H14ClNO4/c20-14-9-10-16(24-12-13-5-2-1-3-6-13)17(11-14)25-18-8-4-7-15(21-18)19(22)23/h1-11H,12H2,(H,22,23)
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n/an/a 794n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor

Bioorg Med Chem Lett 18: 1592-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.071
BindingDB Entry DOI: 10.7270/Q2N58NNN
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%