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PubMed code 18307287

Compile data set for download or QSAR
Found 60 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373490
PNG
(CHEMBL405260)
Show SMILES FCCOc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-7-2-1-6-19(20)24-12-10-23(11-13-24)16-17-15-18-5-3-4-9-25(18)22-17/h1-7,9,15H,8,10-14,16H2
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 46n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373490
PNG
(CHEMBL405260)
Show SMILES FCCOc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-7-2-1-6-19(20)24-12-10-23(11-13-24)16-17-15-18-5-3-4-9-25(18)22-17/h1-7,9,15H,8,10-14,16H2
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 79n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373494
PNG
(CHEMBL272395)
Show SMILES Brc1cccc(n1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C17H18BrN5/c18-16-5-3-6-17(20-16)22-10-8-21(9-11-22)13-14-12-19-23-7-2-1-4-15(14)23/h1-7,12H,8-11,13H2
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 150n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373497
PNG
(CHEMBL411437)
Show SMILES FCCOc1ccccc1N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-7-2-1-6-19(20)24-12-10-23(11-13-24)16-17-15-22-25-9-4-3-5-18(17)25/h1-7,9,15H,8,10-14,16H2
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 150n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373497
PNG
(CHEMBL411437)
Show SMILES FCCOc1ccccc1N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-7-2-1-6-19(20)24-12-10-23(11-13-24)16-17-15-22-25-9-4-3-5-18(17)25/h1-7,9,15H,8,10-14,16H2
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 180n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373494
PNG
(CHEMBL272395)
Show SMILES Brc1cccc(n1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C17H18BrN5/c18-16-5-3-6-17(20-16)22-10-8-21(9-11-22)13-14-12-19-23-7-2-1-4-15(14)23/h1-7,12H,8-11,13H2
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 210n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373495
PNG
(CHEMBL270056)
Show SMILES Fc1cccc(n1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C17H18FN5/c18-16-5-3-6-17(20-16)22-10-8-21(9-11-22)13-14-12-19-23-7-2-1-4-15(14)23/h1-7,12H,8-11,13H2
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 220n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50373497
PNG
(CHEMBL411437)
Show SMILES FCCOc1ccccc1N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-7-2-1-6-19(20)24-12-10-23(11-13-24)16-17-15-22-25-9-4-3-5-18(17)25/h1-7,9,15H,8,10-14,16H2
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 320n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373495
PNG
(CHEMBL270056)
Show SMILES Fc1cccc(n1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C17H18FN5/c18-16-5-3-6-17(20-16)22-10-8-21(9-11-22)13-14-12-19-23-7-2-1-4-15(14)23/h1-7,12H,8-11,13H2
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 330n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(PIG)		BDBM50073805
PNG
(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H19ClN4/c19-16-4-6-17(7-5-16)22-11-9-21(10-12-22)14-15-13-20-23-8-2-1-3-18(15)23/h1-8,13H,9-12,14H2
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 380n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranes

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50373494
PNG
(CHEMBL272395)
Show SMILES Brc1cccc(n1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C17H18BrN5/c18-16-5-3-6-17(20-16)22-10-8-21(9-11-22)13-14-12-19-23-7-2-1-4-15(14)23/h1-7,12H,8-11,13H2
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 410n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373491
PNG
(CHEMBL272396)
Show SMILES Brc1cccc(n1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C17H18BrN5/c18-16-5-3-6-17(19-16)22-10-8-21(9-11-22)13-14-12-15-4-1-2-7-23(15)20-14/h1-7,12H,8-11,13H2
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 550n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50373495
PNG
(CHEMBL270056)
Show SMILES Fc1cccc(n1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C17H18FN5/c18-16-5-3-6-17(20-16)22-10-8-21(9-11-22)13-14-12-19-23-7-2-1-4-15(14)23/h1-7,12H,8-11,13H2
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 590n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373491
PNG
(CHEMBL272396)
Show SMILES Brc1cccc(n1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C17H18BrN5/c18-16-5-3-6-17(19-16)22-10-8-21(9-11-22)13-14-12-15-4-1-2-7-23(15)20-14/h1-7,12H,8-11,13H2
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 880n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(PIG)		BDBM50102712
PNG
(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2
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 900n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranes

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50373491
PNG
(CHEMBL272396)
Show SMILES Brc1cccc(n1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C17H18BrN5/c18-16-5-3-6-17(19-16)22-10-8-21(9-11-22)13-14-12-15-4-1-2-7-23(15)20-14/h1-7,12H,8-11,13H2
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 930n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50373490
PNG
(CHEMBL405260)
Show SMILES FCCOc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-7-2-1-6-19(20)24-12-10-23(11-13-24)16-17-15-18-5-3-4-9-25(18)22-17/h1-7,9,15H,8,10-14,16H2
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 940n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(PIG)		BDBM50373494
PNG
(CHEMBL272395)
Show SMILES Brc1cccc(n1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C17H18BrN5/c18-16-5-3-6-17(20-16)22-10-8-21(9-11-22)13-14-12-19-23-7-2-1-4-15(14)23/h1-7,12H,8-11,13H2
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 1.20E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranes

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(PIG)		BDBM50373492
PNG
(CHEMBL272602)
Show SMILES Oc1ccccc1N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H20N4O/c23-18-7-2-1-6-17(18)21-11-9-20(10-12-21)14-15-13-19-22-8-4-3-5-16(15)22/h1-8,13,23H,9-12,14H2
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 1.50E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranes

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373498
PNG
(CHEMBL405292)
Show SMILES Fc1cccc(n1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C17H18FN5/c18-16-5-3-6-17(19-16)22-10-8-21(9-11-22)13-14-12-15-4-1-2-7-23(15)20-14/h1-7,12H,8-11,13H2
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 1.70E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50373492
PNG
(CHEMBL272602)
Show SMILES Oc1ccccc1N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H20N4O/c23-18-7-2-1-6-17(18)21-11-9-20(10-12-21)14-15-13-19-22-8-4-3-5-16(15)22/h1-8,13,23H,9-12,14H2
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 2.20E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50073805
PNG
(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H19ClN4/c19-16-4-6-17(7-5-16)22-11-9-21(10-12-22)14-15-13-20-23-8-2-1-3-18(15)23/h1-8,13H,9-12,14H2
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 2.20E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(Sus scrofa)		BDBM50373497
PNG
(CHEMBL411437)
Show SMILES FCCOc1ccccc1N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-7-2-1-6-19(20)24-12-10-23(11-13-24)16-17-15-22-25-9-4-3-5-18(17)25/h1-7,9,15H,8,10-14,16H2
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 2.50E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membrane

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(Sus scrofa)		BDBM50073805
PNG
(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H19ClN4/c19-16-4-6-17(7-5-16)22-11-9-21(10-12-22)14-15-13-20-23-8-2-1-3-18(15)23/h1-8,13H,9-12,14H2
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 2.80E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membrane

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(Sus scrofa)		BDBM50373492
PNG
(CHEMBL272602)
Show SMILES Oc1ccccc1N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H20N4O/c23-18-7-2-1-6-17(18)21-11-9-20(10-12-21)14-15-13-19-22-8-4-3-5-16(15)22/h1-8,13,23H,9-12,14H2
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 2.80E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membrane

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(PIG)		BDBM50373497
PNG
(CHEMBL411437)
Show SMILES FCCOc1ccccc1N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-7-2-1-6-19(20)24-12-10-23(11-13-24)16-17-15-22-25-9-4-3-5-18(17)25/h1-7,9,15H,8,10-14,16H2
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 2.90E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranes

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50073805
PNG
(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H19ClN4/c19-16-4-6-17(7-5-16)22-11-9-21(10-12-22)14-15-13-20-23-8-2-1-3-18(15)23/h1-8,13H,9-12,14H2
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 2.90E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373498
PNG
(CHEMBL405292)
Show SMILES Fc1cccc(n1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C17H18FN5/c18-16-5-3-6-17(19-16)22-10-8-21(9-11-22)13-14-12-15-4-1-2-7-23(15)20-14/h1-7,12H,8-11,13H2
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 3.40E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50373498
PNG
(CHEMBL405292)
Show SMILES Fc1cccc(n1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C17H18FN5/c18-16-5-3-6-17(19-16)22-10-8-21(9-11-22)13-14-12-15-4-1-2-7-23(15)20-14/h1-7,12H,8-11,13H2
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 3.40E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50102712
PNG
(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2
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 3.40E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50373489
PNG
(CHEMBL407818)
Show SMILES Oc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H20N4O/c23-17-6-4-16(5-7-17)21-11-9-20(10-12-21)14-15-13-19-22-8-2-1-3-18(15)22/h1-8,13,23H,9-12,14H2
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 3.40E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(Sus scrofa)		BDBM50373494
PNG
(CHEMBL272395)
Show SMILES Brc1cccc(n1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C17H18BrN5/c18-16-5-3-6-17(20-16)22-10-8-21(9-11-22)13-14-12-19-23-7-2-1-4-15(14)23/h1-7,12H,8-11,13H2
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 3.90E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membrane

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(PIG)		BDBM50373491
PNG
(CHEMBL272396)
Show SMILES Brc1cccc(n1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C17H18BrN5/c18-16-5-3-6-17(19-16)22-10-8-21(9-11-22)13-14-12-15-4-1-2-7-23(15)20-14/h1-7,12H,8-11,13H2
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 4.40E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranes

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373492
PNG
(CHEMBL272602)
Show SMILES Oc1ccccc1N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H20N4O/c23-18-7-2-1-6-17(18)21-11-9-20(10-12-21)14-15-13-19-22-8-4-3-5-16(15)22/h1-8,13,23H,9-12,14H2
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 4.50E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50073805
PNG
(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H19ClN4/c19-16-4-6-17(7-5-16)22-11-9-21(10-12-22)14-15-13-20-23-8-2-1-3-18(15)23/h1-8,13H,9-12,14H2
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 4.50E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373492
PNG
(CHEMBL272602)
Show SMILES Oc1ccccc1N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H20N4O/c23-18-7-2-1-6-17(18)21-11-9-20(10-12-21)14-15-13-19-22-8-4-3-5-16(15)22/h1-8,13,23H,9-12,14H2
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 4.70E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(Sus scrofa)		BDBM50373490
PNG
(CHEMBL405260)
Show SMILES FCCOc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-7-2-1-6-19(20)24-12-10-23(11-13-24)16-17-15-18-5-3-4-9-25(18)22-17/h1-7,9,15H,8,10-14,16H2
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 4.80E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membrane

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50102712
PNG
(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2
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 5.30E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(PIG)		BDBM50373495
PNG
(CHEMBL270056)
Show SMILES Fc1cccc(n1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C17H18FN5/c18-16-5-3-6-17(20-16)22-10-8-21(9-11-22)13-14-12-19-23-7-2-1-4-15(14)23/h1-7,12H,8-11,13H2
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 5.40E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranes

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(PIG)		BDBM50373496
PNG
(CHEMBL272853)
Show SMILES FCCOc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-6-4-18(5-7-20)24-12-10-23(11-13-24)16-17-15-19-3-1-2-9-25(19)22-17/h1-7,9,15H,8,10-14,16H2
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 5.50E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranes

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(Sus scrofa)		BDBM50102712
PNG
(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2
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 5.50E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membrane

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373489
PNG
(CHEMBL407818)
Show SMILES Oc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H20N4O/c23-17-6-4-16(5-7-17)21-11-9-20(10-12-21)14-15-13-19-22-8-2-1-3-18(15)22/h1-8,13,23H,9-12,14H2
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 6.10E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50102712
PNG
(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2
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 6.30E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(Sus scrofa)		BDBM50373495
PNG
(CHEMBL270056)
Show SMILES Fc1cccc(n1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C17H18FN5/c18-16-5-3-6-17(20-16)22-10-8-21(9-11-22)13-14-12-19-23-7-2-1-4-15(14)23/h1-7,12H,8-11,13H2
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 7.30E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membrane

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50373493
PNG
(CHEMBL272873)
Show SMILES FCCOc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-19-6-4-18(5-7-19)24-12-10-23(11-13-24)16-17-15-22-25-9-2-1-3-20(17)25/h1-7,9,15H,8,10-14,16H2
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 8.70E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(PIG)		BDBM50373498
PNG
(CHEMBL405292)
Show SMILES Fc1cccc(n1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C17H18FN5/c18-16-5-3-6-17(19-16)22-10-8-21(9-11-22)13-14-12-15-4-1-2-7-23(15)20-14/h1-7,12H,8-11,13H2
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 9.70E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranes

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(Sus scrofa)		BDBM50373489
PNG
(CHEMBL407818)
Show SMILES Oc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H20N4O/c23-17-6-4-16(5-7-17)21-11-9-20(10-12-21)14-15-13-19-22-8-2-1-3-18(15)22/h1-8,13,23H,9-12,14H2
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 9.90E+3n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membrane

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(PIG)		BDBM50373490
PNG
(CHEMBL405260)
Show SMILES FCCOc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-7-2-1-6-19(20)24-12-10-23(11-13-24)16-17-15-18-5-3-4-9-25(18)22-17/h1-7,9,15H,8,10-14,16H2
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 1.30E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranes

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(PIG)		BDBM50373493
PNG
(CHEMBL272873)
Show SMILES FCCOc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-19-6-4-18(5-7-19)24-12-10-23(11-13-24)16-17-15-22-25-9-2-1-3-20(17)25/h1-7,9,15H,8,10-14,16H2
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 1.40E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranes

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50373496
PNG
(CHEMBL272853)
Show SMILES FCCOc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-6-4-18(5-7-20)24-12-10-23(11-13-24)16-17-15-19-3-1-2-9-25(19)22-17/h1-7,9,15H,8,10-14,16H2
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 1.50E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(Sus scrofa)		BDBM50373491
PNG
(CHEMBL272396)
Show SMILES Brc1cccc(n1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C17H18BrN5/c18-16-5-3-6-17(19-16)22-10-8-21(9-11-22)13-14-12-15-4-1-2-7-23(15)20-14/h1-7,12H,8-11,13H2
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 1.80E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membrane

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(PIG)		BDBM50373489
PNG
(CHEMBL407818)
Show SMILES Oc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H20N4O/c23-17-6-4-16(5-7-17)21-11-9-20(10-12-21)14-15-13-19-22-8-2-1-3-18(15)22/h1-8,13,23H,9-12,14H2
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 2.47E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranes

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(Sus scrofa)		BDBM50373496
PNG
(CHEMBL272853)
Show SMILES FCCOc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-6-4-18(5-7-20)24-12-10-23(11-13-24)16-17-15-19-3-1-2-9-25(19)22-17/h1-7,9,15H,8,10-14,16H2
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 2.90E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membrane

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(Sus scrofa)		BDBM50373498
PNG
(CHEMBL405292)
Show SMILES Fc1cccc(n1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C17H18FN5/c18-16-5-3-6-17(19-16)22-10-8-21(9-11-22)13-14-12-15-4-1-2-7-23(15)20-14/h1-7,12H,8-11,13H2
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 3.00E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membrane

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373496
PNG
(CHEMBL272853)
Show SMILES FCCOc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-6-4-18(5-7-20)24-12-10-23(11-13-24)16-17-15-19-3-1-2-9-25(19)22-17/h1-7,9,15H,8,10-14,16H2
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 3.00E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(1A) dopamine receptor


(Sus scrofa)		BDBM50373493
PNG
(CHEMBL272873)
Show SMILES FCCOc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-19-6-4-18(5-7-19)24-12-10-23(11-13-24)16-17-15-22-25-9-2-1-3-20(17)25/h1-7,9,15H,8,10-14,16H2
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 3.30E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membrane

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373496
PNG
(CHEMBL272853)
Show SMILES FCCOc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-20-6-4-18(5-7-20)24-12-10-23(11-13-24)16-17-15-19-3-1-2-9-25(19)22-17/h1-7,9,15H,8,10-14,16H2
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 5.00E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373493
PNG
(CHEMBL272873)
Show SMILES FCCOc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-19-6-4-18(5-7-19)24-12-10-23(11-13-24)16-17-15-22-25-9-2-1-3-20(17)25/h1-7,9,15H,8,10-14,16H2
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 6.60E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373493
PNG
(CHEMBL272873)
Show SMILES FCCOc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C20H23FN4O/c21-8-14-26-19-6-4-18(5-7-19)24-12-10-23(11-13-24)16-17-15-22-25-9-2-1-3-20(17)25/h1-7,9,15H,8,10-14,16H2
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 7.90E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50373489
PNG
(CHEMBL407818)
Show SMILES Oc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1
Show InChI InChI=1S/C18H20N4O/c23-17-6-4-16(5-7-17)21-11-9-20(10-12-21)14-15-13-19-22-8-2-1-3-18(15)22/h1-8,13,23H,9-12,14H2
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 8.70E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cells

J Med Chem 51: 1800-10 (2008)


Article DOI: 10.1021/jm701375u
BindingDB Entry DOI: 10.7270/Q2RB75FF
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%