Found 38 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260622
((S)-7-(Toluene-4-sulfonyl)-1,4-dioxa-7-aza-spiro[4...)Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CC2(C[C@H]1C(=O)NO)OCCO2 |r| Show InChI InChI=1S/C14H18N2O6S/c1-10-2-4-11(5-3-10)23(19,20)16-9-14(21-6-7-22-14)8-12(16)13(17)15-18/h2-5,12,18H,6-9H2,1H3,(H,15,17)/t12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260661
((S)-2-(Toluene-4-sulfonyl)-6,10-dioxa-2-aza-spiro-...)Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CC2(C[C@H]1C(=O)NO)OCCCO2 |r| Show InChI InChI=1S/C15H20N2O6S/c1-11-3-5-12(6-4-11)24(20,21)17-10-15(22-7-2-8-23-15)9-13(17)14(18)16-19/h3-6,13,19H,2,7-10H2,1H3,(H,16,18)/t13-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260662
((S)-2-(Toluene-4-sulfonyl)-6,11-dioxa-2-aza-spiro-...)Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CC2(C[C@H]1C(=O)NO)OCCCCO2 |r| Show InChI InChI=1S/C16H22N2O6S/c1-12-4-6-13(7-5-12)25(21,22)18-11-16(10-14(18)15(19)17-20)23-8-2-3-9-24-16/h4-7,14,20H,2-3,8-11H2,1H3,(H,17,19)/t14-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260663
((S)-7-Benzenesulfonyl-1,4-dioxa-7-aza-spiro[4.4]-n...)Show SMILES ONC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCO2 |r| Show InChI InChI=1S/C13H16N2O6S/c16-12(14-17)11-8-13(20-6-7-21-13)9-15(11)22(18,19)10-4-2-1-3-5-10/h1-5,11,17H,6-9H2,(H,14,16)/t11-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50247539
(CHEMBL472915 | N-((3S,5S)-1-((E)-3-(3,4-dimethoxyp...)Show SMILES COc1ccc(\C=C\C(=O)N2C[C@H](C[C@H]2C(=O)NO)NC(=O)c2cccnc2)cc1OC |r| Show InChI InChI=1S/C22H24N4O6/c1-31-18-7-5-14(10-19(18)32-2)6-8-20(27)26-13-16(11-17(26)22(29)25-30)24-21(28)15-4-3-9-23-12-15/h3-10,12,16-17,30H,11,13H2,1-2H3,(H,24,28)(H,25,29)/b8-6+/t16-,17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260664
((S)-2-Benzenesulfonyl-6,10-dioxa-2-aza-spiro[4.5]-...)Show SMILES ONC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCCO2 |r| Show InChI InChI=1S/C14H18N2O6S/c17-13(15-18)12-9-14(21-7-4-8-22-14)10-16(12)23(19,20)11-5-2-1-3-6-11/h1-3,5-6,12,18H,4,7-10H2,(H,15,17)/t12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260665
((S)-2-Benzenesulfonyl-6,11-dioxa-2-aza-spiro[4.6]-...)Show SMILES ONC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCCCO2 |r| Show InChI InChI=1S/C15H20N2O6S/c18-14(16-19)13-10-15(22-8-4-5-9-23-15)11-17(13)24(20,21)12-6-2-1-3-7-12/h1-3,6-7,13,19H,4-5,8-11H2,(H,16,18)/t13-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50253922
(4-Hydroxy-1-(toluene-4-sulfonyl)-pyrrolidine-2-car...)Show SMILES COC(=O)[C@@H]1C[C@@H](O)CN1S(=O)(=O)c1ccc(C)cc1 |r| Show InChI InChI=1S/C13H17NO5S/c1-9-3-5-11(6-4-9)20(17,18)14-8-10(15)7-12(14)13(16)19-2/h3-6,10,12,15H,7-8H2,1-2H3/t10-,12+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260537
((S)-7-(Toluene-4-sulfonyl)-1,4-dioxa-7-aza-spiro[4...)Show SMILES COC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccc(C)cc1)OCCO2 |r| Show InChI InChI=1S/C15H19NO6S/c1-11-3-5-12(6-4-11)23(18,19)16-10-15(21-7-8-22-15)9-13(16)14(17)20-2/h3-6,13H,7-10H2,1-2H3/t13-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260617
((S)-2-(Toluene-4-sulfonyl)-6,10-dioxa-2-aza-spiro[...)Show SMILES COC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccc(C)cc1)OCCCO2 |r| Show InChI InChI=1S/C16H21NO6S/c1-12-4-6-13(7-5-12)24(19,20)17-11-16(22-8-3-9-23-16)10-14(17)15(18)21-2/h4-7,14H,3,8-11H2,1-2H3/t14-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260619
((S)-7-Benzenesulfonyl-1,4-dioxa-7-aza-spiro[4.4]no...)Show SMILES COC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCO2 |r| Show InChI InChI=1S/C14H17NO6S/c1-19-13(16)12-9-14(20-7-8-21-14)10-15(12)22(17,18)11-5-3-2-4-6-11/h2-6,12H,7-10H2,1H3/t12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260618
((S)-2-(Toluene-4-sulfonyl)-6,11-dioxa-2-aza-spiro-...)Show SMILES COC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccc(C)cc1)OCCCCO2 |r| Show InChI InChI=1S/C17H23NO6S/c1-13-5-7-14(8-6-13)25(20,21)18-12-17(11-15(18)16(19)22-2)23-9-3-4-10-24-17/h5-8,15H,3-4,9-12H2,1-2H3/t15-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260507
(4-Oxo-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxy...)Show SMILES COC(=O)[C@@H]1CC(=O)CN1S(=O)(=O)c1ccc(C)cc1 |r| Show InChI InChI=1S/C13H15NO5S/c1-9-3-5-11(6-4-9)20(17,18)14-8-10(15)7-12(14)13(16)19-2/h3-6,12H,7-8H2,1-2H3/t12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50253923
(1-Benzenesulfonyl-4-hydroxy-pyrrolidine-2-carboxyl...)Show SMILES COC(=O)[C@@H]1C[C@@H](O)CN1S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C12H15NO5S/c1-18-12(15)11-7-9(14)8-13(11)19(16,17)10-5-3-2-4-6-10/h2-6,9,11,14H,7-8H2,1H3/t9-,11+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260620
((S)-2-Benzenesulfonyl-6,10-dioxa-2-aza-spiro-[4.5]...)Show SMILES COC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCCO2 |r| Show InChI InChI=1S/C15H19NO6S/c1-20-14(17)13-10-15(21-8-5-9-22-15)11-16(13)23(18,19)12-6-3-2-4-7-12/h2-4,6-7,13H,5,8-11H2,1H3/t13-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260621
((S)-2-Benzenesulfonyl-6,11-dioxa-2-aza-spiro[4.6]-...)Show SMILES COC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCCCO2 |r| Show InChI InChI=1S/C16H21NO6S/c1-21-15(18)14-11-16(22-9-5-6-10-23-16)12-17(14)24(19,20)13-7-3-2-4-8-13/h2-4,7-8,14H,5-6,9-12H2,1H3/t14-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260508
(1-Benzenesulfonyl-4-oxo-pyrrolidine-2-carboxylicac...)Show SMILES COC(=O)[C@@H]1CC(=O)CN1S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C12H13NO5S/c1-18-12(15)11-7-9(14)8-13(11)19(16,17)10-5-3-2-4-6-10/h2-6,11H,7-8H2,1H3/t11-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50253924
(4-Hydroxy-1-methanesulfonyl-pyrrolidine-2-carboxyl...)Show InChI InChI=1S/C7H13NO5S/c1-13-7(10)6-3-5(9)4-8(6)14(2,11)12/h5-6,9H,3-4H2,1-2H3/t5-,6+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50260509
(1-Methanesulfonyl-4-oxo-pyrrolidine-2-carboxylicac...)Show InChI InChI=1S/C7H11NO5S/c1-13-7(10)6-3-5(9)4-8(6)14(2,11)12/h6H,3-4H2,1-2H3/t6-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50253922
(4-Hydroxy-1-(toluene-4-sulfonyl)-pyrrolidine-2-car...)Show SMILES COC(=O)[C@@H]1C[C@@H](O)CN1S(=O)(=O)c1ccc(C)cc1 |r| Show InChI InChI=1S/C13H17NO5S/c1-9-3-5-11(6-4-9)20(17,18)14-8-10(15)7-12(14)13(16)19-2/h3-6,10,12,15H,7-8H2,1-2H3/t10-,12+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50253924
(4-Hydroxy-1-methanesulfonyl-pyrrolidine-2-carboxyl...)Show InChI InChI=1S/C7H13NO5S/c1-13-7(10)6-3-5(9)4-8(6)14(2,11)12/h5-6,9H,3-4H2,1-2H3/t5-,6+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260622
((S)-7-(Toluene-4-sulfonyl)-1,4-dioxa-7-aza-spiro[4...)Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CC2(C[C@H]1C(=O)NO)OCCO2 |r| Show InChI InChI=1S/C14H18N2O6S/c1-10-2-4-11(5-3-10)23(19,20)16-9-14(21-6-7-22-14)8-12(16)13(17)15-18/h2-5,12,18H,6-9H2,1H3,(H,15,17)/t12-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50253923
(1-Benzenesulfonyl-4-hydroxy-pyrrolidine-2-carboxyl...)Show SMILES COC(=O)[C@@H]1C[C@@H](O)CN1S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C12H15NO5S/c1-18-12(15)11-7-9(14)8-13(11)19(16,17)10-5-3-2-4-6-10/h2-6,9,11,14H,7-8H2,1H3/t9-,11+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260507
(4-Oxo-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxy...)Show SMILES COC(=O)[C@@H]1CC(=O)CN1S(=O)(=O)c1ccc(C)cc1 |r| Show InChI InChI=1S/C13H15NO5S/c1-9-3-5-11(6-4-9)20(17,18)14-8-10(15)7-12(14)13(16)19-2/h3-6,12H,7-8H2,1-2H3/t12-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.49E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260663
((S)-7-Benzenesulfonyl-1,4-dioxa-7-aza-spiro[4.4]-n...)Show SMILES ONC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCO2 |r| Show InChI InChI=1S/C13H16N2O6S/c16-12(14-17)11-8-13(20-6-7-21-13)9-15(11)22(18,19)10-4-2-1-3-5-10/h1-5,11,17H,6-9H2,(H,14,16)/t11-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260661
((S)-2-(Toluene-4-sulfonyl)-6,10-dioxa-2-aza-spiro-...)Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CC2(C[C@H]1C(=O)NO)OCCCO2 |r| Show InChI InChI=1S/C15H20N2O6S/c1-11-3-5-12(6-4-11)24(20,21)17-10-15(22-7-2-8-23-15)9-13(17)14(18)16-19/h3-6,13,19H,2,7-10H2,1H3,(H,16,18)/t13-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260662
((S)-2-(Toluene-4-sulfonyl)-6,11-dioxa-2-aza-spiro-...)Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CC2(C[C@H]1C(=O)NO)OCCCCO2 |r| Show InChI InChI=1S/C16H22N2O6S/c1-12-4-6-13(7-5-12)25(21,22)18-11-16(10-14(18)15(19)17-20)23-8-2-3-9-24-16/h4-7,14,20H,2-3,8-11H2,1H3,(H,17,19)/t14-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260508
(1-Benzenesulfonyl-4-oxo-pyrrolidine-2-carboxylicac...)Show SMILES COC(=O)[C@@H]1CC(=O)CN1S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C12H13NO5S/c1-18-12(15)11-7-9(14)8-13(11)19(16,17)10-5-3-2-4-6-10/h2-6,11H,7-8H2,1H3/t11-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260664
((S)-2-Benzenesulfonyl-6,10-dioxa-2-aza-spiro[4.5]-...)Show SMILES ONC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCCO2 |r| Show InChI InChI=1S/C14H18N2O6S/c17-13(15-18)12-9-14(21-7-4-8-22-14)10-16(12)23(19,20)11-5-2-1-3-6-11/h1-3,5-6,12,18H,4,7-10H2,(H,15,17)/t12-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260509
(1-Methanesulfonyl-4-oxo-pyrrolidine-2-carboxylicac...)Show InChI InChI=1S/C7H11NO5S/c1-13-7(10)6-3-5(9)4-8(6)14(2,11)12/h6H,3-4H2,1-2H3/t6-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260665
((S)-2-Benzenesulfonyl-6,11-dioxa-2-aza-spiro[4.6]-...)Show SMILES ONC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCCCO2 |r| Show InChI InChI=1S/C15H20N2O6S/c18-14(16-19)13-10-15(22-8-4-5-9-23-15)11-17(13)24(20,21)12-6-2-1-3-7-12/h1-3,6-7,13,19H,4-5,8-11H2,(H,16,18)/t13-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.07E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260618
((S)-2-(Toluene-4-sulfonyl)-6,11-dioxa-2-aza-spiro-...)Show SMILES COC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccc(C)cc1)OCCCCO2 |r| Show InChI InChI=1S/C17H23NO6S/c1-13-5-7-14(8-6-13)25(20,21)18-12-17(11-15(18)16(19)22-2)23-9-3-4-10-24-17/h5-8,15H,3-4,9-12H2,1-2H3/t15-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.24E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260621
((S)-2-Benzenesulfonyl-6,11-dioxa-2-aza-spiro[4.6]-...)Show SMILES COC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCCCO2 |r| Show InChI InChI=1S/C16H21NO6S/c1-21-15(18)14-11-16(22-9-5-6-10-23-16)12-17(14)24(19,20)13-7-3-2-4-8-13/h2-4,7-8,14H,5-6,9-12H2,1H3/t14-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.35E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50247539
(CHEMBL472915 | N-((3S,5S)-1-((E)-3-(3,4-dimethoxyp...)Show SMILES COc1ccc(\C=C\C(=O)N2C[C@H](C[C@H]2C(=O)NO)NC(=O)c2cccnc2)cc1OC |r| Show InChI InChI=1S/C22H24N4O6/c1-31-18-7-5-14(10-19(18)32-2)6-8-20(27)26-13-16(11-17(26)22(29)25-30)24-21(28)15-4-3-9-23-12-15/h3-10,12,16-17,30H,11,13H2,1-2H3,(H,24,28)(H,25,29)/b8-6+/t16-,17-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.42E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260619
((S)-7-Benzenesulfonyl-1,4-dioxa-7-aza-spiro[4.4]no...)Show SMILES COC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCO2 |r| Show InChI InChI=1S/C14H17NO6S/c1-19-13(16)12-9-14(20-7-8-21-14)10-15(12)22(17,18)11-5-3-2-4-6-11/h2-6,12H,7-10H2,1H3/t12-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.51E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260537
((S)-7-(Toluene-4-sulfonyl)-1,4-dioxa-7-aza-spiro[4...)Show SMILES COC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccc(C)cc1)OCCO2 |r| Show InChI InChI=1S/C15H19NO6S/c1-11-3-5-12(6-4-11)23(18,19)16-10-15(21-7-8-22-15)9-13(16)14(17)20-2/h3-6,13H,7-10H2,1-2H3/t13-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.56E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260620
((S)-2-Benzenesulfonyl-6,10-dioxa-2-aza-spiro-[4.5]...)Show SMILES COC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCCO2 |r| Show InChI InChI=1S/C15H19NO6S/c1-20-14(17)13-10-15(21-8-5-9-22-15)11-16(13)23(18,19)12-6-3-2-4-7-12/h2-4,6-7,13H,5,8-11H2,1H3/t13-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.68E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50260617
((S)-2-(Toluene-4-sulfonyl)-6,10-dioxa-2-aza-spiro[...)Show SMILES COC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccc(C)cc1)OCCCO2 |r| Show InChI InChI=1S/C16H21NO6S/c1-12-4-6-13(7-5-12)24(19,20)17-11-16(22-8-3-9-23-16)10-14(17)15(18)21-2/h4-7,14H,3,8-11H2,1-2H3/t14-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.74E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N (unknown origin) |
Bioorg Med Chem 16: 5398-404 (2008)
Article DOI: 10.1016/j.bmc.2008.04.027
BindingDB Entry DOI: 10.7270/Q22B8XTN |
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