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PubMed code 18571419

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aminopeptidase N


(Sus scrofa (Pig))		BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
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n/an/a 8.50E+3n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
72 kDa type IV collagenase


(Homo sapiens (Human))		BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
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n/an/a 9.50E+3n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of MMP2

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252583
PNG
((2R)-N-[5-(4-Methoxyphenyl)-1,3,4-thiadiazol-2-yl]...)
Show SMILES COc1ccc(cc1)-c1nnc(NC(=O)[C@@H](C)NC(=O)\C=C\c2ccccc2)s1 |r|
Show InChI InChI=1S/C21H20N4O3S/c1-14(22-18(26)13-8-15-6-4-3-5-7-15)19(27)23-21-25-24-20(29-21)16-9-11-17(28-2)12-10-16/h3-14H,1-2H3,(H,22,26)(H,23,25,27)/b13-8+/t14-/m1/s1
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n/an/a 3.14E+4n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252587
PNG
((2R)-N-[5-(4-Bromophenyl)-1,3,4-thiadiazol-2-yl]-2...)
Show SMILES C[C@@H](NC(=O)\C=C\c1ccc(O)cc1)C(=O)Nc1nnc(s1)-c1ccc(Br)cc1 |r|
Show InChI InChI=1S/C20H17BrN4O3S/c1-12(22-17(27)11-4-13-2-9-16(26)10-3-13)18(28)23-20-25-24-19(29-20)14-5-7-15(21)8-6-14/h2-12,26H,1H3,(H,22,27)(H,23,25,28)/b11-4+/t12-/m1/s1
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n/an/a 3.53E+4n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50251877
PNG
((2R)-N-[5-(4-Nitrorophenyl)-1,3,4-thiadiazol-2-yl]...)
Show SMILES COc1ccc(\C=C\C(=O)N[C@H](C)C(=O)Nc2nnc(s2)-c2ccc(cc2)[N+]([O-])=O)cc1 |r|
Show InChI InChI=1S/C21H19N5O5S/c1-13(22-18(27)12-5-14-3-10-17(31-2)11-4-14)19(28)23-21-25-24-20(32-21)15-6-8-16(9-7-15)26(29)30/h3-13H,1-2H3,(H,22,27)(H,23,25,28)/b12-5+/t13-/m1/s1
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n/an/a 4.46E+4n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252640
PNG
((2R)-N-[5-(4-Nitrorophenyl)-1,3,4-thiadiazol-2-yl]...)
Show SMILES C[C@@H](NC(=O)\C=C\c1ccc(O)cc1)C(=O)Nc1nnc(s1)-c1ccc(cc1)[N+]([O-])=O |r|
Show InChI InChI=1S/C20H17N5O5S/c1-12(21-17(27)11-4-13-2-9-16(26)10-3-13)18(28)22-20-24-23-19(31-20)14-5-7-15(8-6-14)25(29)30/h2-12,26H,1H3,(H,21,27)(H,22,24,28)/b11-4+/t12-/m1/s1
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n/an/a 5.41E+4n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252642
PNG
((2R)-N-[5-(4-Methoxyphenyl)-1,3,4-thiadiazol-2-yl]...)
Show SMILES COc1ccc(cc1)-c1nnc(NC(=O)[C@@H](C)NC(=O)\C=C\c2ccc(O)cc2)s1 |r|
Show InChI InChI=1S/C21H20N4O4S/c1-13(22-18(27)12-5-14-3-8-16(26)9-4-14)19(28)23-21-25-24-20(30-21)15-6-10-17(29-2)11-7-15/h3-13,26H,1-2H3,(H,22,27)(H,23,25,28)/b12-5+/t13-/m1/s1
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n/an/a 6.88E+4n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252023
PNG
((2R)-N-[5-(4-Methoxyphenyl)-1,3,4-thiadiazol-2-yl]...)
Show SMILES COc1ccc(\C=C\C(=O)N[C@H](C)C(=O)Nc2nnc(s2)-c2ccc(OC)cc2)cc1 |r|
Show InChI InChI=1S/C22H22N4O4S/c1-14(23-19(27)13-6-15-4-9-17(29-2)10-5-15)20(28)24-22-26-25-21(31-22)16-7-11-18(30-3)12-8-16/h4-14H,1-3H3,(H,23,27)(H,24,26,28)/b13-6+/t14-/m1/s1
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n/an/a 7.85E+4n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252532
PNG
((2R)-N-[5-(4-Nitrorophenyl)-1,3,4-thiadiazol-2-yl]...)
Show SMILES C[C@@H](NC(=O)\C=C\c1ccccc1)C(=O)Nc1nnc(s1)-c1ccc(cc1)[N+]([O-])=O |r|
Show InChI InChI=1S/C20H17N5O4S/c1-13(21-17(26)12-7-14-5-3-2-4-6-14)18(27)22-20-24-23-19(30-20)15-8-10-16(11-9-15)25(28)29/h2-13H,1H3,(H,21,26)(H,22,24,27)/b12-7+/t13-/m1/s1
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n/an/a 8.47E+4n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50251874
PNG
((2R)-N-[5-(4-Fluorophenyl)-1,3,4-thiadiazol-2-yl]-...)
Show SMILES COc1ccc(\C=C\C(=O)N[C@H](C)C(=O)Nc2nnc(s2)-c2ccc(F)cc2)cc1 |r|
Show InChI InChI=1S/C21H19FN4O3S/c1-13(23-18(27)12-5-14-3-10-17(29-2)11-4-14)19(28)24-21-26-25-20(30-21)15-6-8-16(22)9-7-15/h3-13H,1-2H3,(H,23,27)(H,24,26,28)/b12-5+/t13-/m1/s1
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n/an/a 9.07E+4n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252586
PNG
((2R)-N-[5-(4-Chlorophenyl)-1,3,4-thiadiazol-2-yl]-...)
Show SMILES C[C@@H](NC(=O)\C=C\c1ccc(O)cc1)C(=O)Nc1nnc(s1)-c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C20H17ClN4O3S/c1-12(22-17(27)11-4-13-2-9-16(26)10-3-13)18(28)23-20-25-24-19(29-20)14-5-7-15(21)8-6-14/h2-12,26H,1H3,(H,22,27)(H,23,25,28)/b11-4+/t12-/m1/s1
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n/an/a 1.05E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50251876
PNG
((2R)-N-[5-(4-Bromophenyl)-1,3,4-thiadiazol-2-yl]-2...)
Show SMILES COc1ccc(\C=C\C(=O)N[C@H](C)C(=O)Nc2nnc(s2)-c2ccc(Br)cc2)cc1 |r|
Show InChI InChI=1S/C21H19BrN4O3S/c1-13(23-18(27)12-5-14-3-10-17(29-2)11-4-14)19(28)24-21-26-25-20(30-21)15-6-8-16(22)9-7-15/h3-13H,1-2H3,(H,23,27)(H,24,26,28)/b12-5+/t13-/m1/s1
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n/an/a 1.08E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252531
PNG
((2R)-N-[5-(4-Bromophenyl)-1,3,4-thiadiazol-2-yl]-2...)
Show SMILES C[C@@H](NC(=O)\C=C\c1ccccc1)C(=O)Nc1nnc(s1)-c1ccc(Br)cc1 |r|
Show InChI InChI=1S/C20H17BrN4O2S/c1-13(22-17(26)12-7-14-5-3-2-4-6-14)18(27)23-20-25-24-19(28-20)15-8-10-16(21)11-9-15/h2-13H,1H3,(H,22,26)(H,23,25,27)/b12-7+/t13-/m1/s1
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n/an/a 1.15E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252585
PNG
((2R)-N-[5-(4-Fluorophenyl)-1,3,4-thiadiazol-2-yl]-...)
Show SMILES C[C@@H](NC(=O)\C=C\c1ccc(O)cc1)C(=O)Nc1nnc(s1)-c1ccc(F)cc1 |r|
Show InChI InChI=1S/C20H17FN4O3S/c1-12(22-17(27)11-4-13-2-9-16(26)10-3-13)18(28)23-20-25-24-19(29-20)14-5-7-15(21)8-6-14/h2-12,26H,1H3,(H,22,27)(H,23,25,28)/b11-4+/t12-/m1/s1
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n/an/a 1.15E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252584
PNG
((2R)-N-[5-Phenyl-1,3,4-thiadiazol-2-yl]-2-[(p-coum...)
Show SMILES C[C@@H](NC(=O)\C=C\c1ccc(O)cc1)C(=O)Nc1nnc(s1)-c1ccccc1 |r|
Show InChI InChI=1S/C20H18N4O3S/c1-13(21-17(26)12-9-14-7-10-16(25)11-8-14)18(27)22-20-24-23-19(28-20)15-5-3-2-4-6-15/h2-13,25H,1H3,(H,21,26)(H,22,24,27)/b12-9+/t13-/m1/s1
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n/an/a 1.24E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252641
PNG
((2R)-N-[5-(4-Methylphenyl)-1,3,4-thiadiazol-2-yl]-...)
Show SMILES C[C@@H](NC(=O)\C=C\c1ccc(O)cc1)C(=O)Nc1nnc(s1)-c1ccc(C)cc1 |r|
Show InChI InChI=1S/C21H20N4O3S/c1-13-3-8-16(9-4-13)20-24-25-21(29-20)23-19(28)14(2)22-18(27)12-7-15-5-10-17(26)11-6-15/h3-12,14,26H,1-2H3,(H,22,27)(H,23,25,28)/b12-7+/t14-/m1/s1
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n/an/a 1.27E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252643
PNG
((2R)-N-[5-Phenyl-1,3,4-thiadiazol-2-yl]-2-[(pmetho...)
Show SMILES COc1ccc(\C=C\C(=O)N[C@H](C)C(=O)Nc2nnc(s2)-c2ccccc2)cc1 |r|
Show InChI InChI=1S/C21H20N4O3S/c1-14(22-18(26)13-10-15-8-11-17(28-2)12-9-15)19(27)23-21-25-24-20(29-21)16-6-4-3-5-7-16/h3-14H,1-2H3,(H,22,26)(H,23,25,27)/b13-10+/t14-/m1/s1
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n/an/a 1.31E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50251875
PNG
((2R)-N-[5-(4-Chlorophenyl)-1,3,4-thiadiazol-2-yl]-...)
Show SMILES COc1ccc(\C=C\C(=O)N[C@H](C)C(=O)Nc2nnc(s2)-c2ccc(Cl)cc2)cc1 |r|
Show InChI InChI=1S/C21H19ClN4O3S/c1-13(23-18(27)12-5-14-3-10-17(29-2)11-4-14)19(28)24-21-26-25-20(30-21)15-6-8-16(22)9-7-15/h3-13H,1-2H3,(H,23,27)(H,24,26,28)/b12-5+/t13-/m1/s1
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n/an/a 1.35E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50251922
PNG
((2R)-N-[5-(4-Methylphenyl)-1,3,4-thiadiazol-2-yl]-...)
Show SMILES COc1ccc(\C=C\C(=O)N[C@H](C)C(=O)Nc2nnc(s2)-c2ccc(C)cc2)cc1 |r|
Show InChI InChI=1S/C22H22N4O3S/c1-14-4-9-17(10-5-14)21-25-26-22(30-21)24-20(28)15(2)23-19(27)13-8-16-6-11-18(29-3)12-7-16/h4-13,15H,1-3H3,(H,23,27)(H,24,26,28)/b13-8+/t15-/m1/s1
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n/an/a 1.41E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252530
PNG
((2R)-N-[5-(4-Chlorophenyl)-1,3,4-thiadiazol-2-yl]-...)
Show SMILES C[C@@H](NC(=O)\C=C\c1ccccc1)C(=O)Nc1nnc(s1)-c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C20H17ClN4O2S/c1-13(22-17(26)12-7-14-5-3-2-4-6-14)18(27)23-20-25-24-19(28-20)15-8-10-16(21)11-9-15/h2-13H,1H3,(H,22,26)(H,23,25,27)/b12-7+/t13-/m1/s1
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n/an/a 1.53E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252529
PNG
((2R)-N-[5-(4-Fluorophenyl)-1,3,4-thiadiazol-2-yl]-...)
Show SMILES C[C@@H](NC(=O)\C=C\c1ccccc1)C(=O)Nc1nnc(s1)-c1ccc(F)cc1 |r|
Show InChI InChI=1S/C20H17FN4O2S/c1-13(22-17(26)12-7-14-5-3-2-4-6-14)18(27)23-20-25-24-19(28-20)15-8-10-16(21)11-9-15/h2-13H,1H3,(H,22,26)(H,23,25,27)/b12-7+/t13-/m1/s1
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n/an/a 1.83E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252533
PNG
((2R)-N-[5-(4-Methylphenyl)-1,3,4-thiadiazol-2-yl]-...)
Show SMILES C[C@@H](NC(=O)\C=C\c1ccccc1)C(=O)Nc1nnc(s1)-c1ccc(C)cc1 |r|
Show InChI InChI=1S/C21H20N4O2S/c1-14-8-11-17(12-9-14)20-24-25-21(28-20)23-19(27)15(2)22-18(26)13-10-16-6-4-3-5-7-16/h3-13,15H,1-2H3,(H,22,26)(H,23,25,27)/b13-10+/t15-/m1/s1
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n/an/a 2.06E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50252490
PNG
((2R)-N-[5-phenyl-1,3,4-thiadiazol-2-yl]-2-[(cinnam...)
Show SMILES C[C@@H](NC(=O)\C=C\c1ccccc1)C(=O)Nc1nnc(s1)-c1ccccc1 |r|
Show InChI InChI=1S/C20H18N4O2S/c1-14(21-17(25)13-12-15-8-4-2-5-9-15)18(26)22-20-24-23-19(27-20)16-10-6-3-7-11-16/h2-14H,1H3,(H,21,25)(H,22,24,26)/b13-12+/t14-/m1/s1
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n/an/a 2.16E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))		BDBM50251877
PNG
((2R)-N-[5-(4-Nitrorophenyl)-1,3,4-thiadiazol-2-yl]...)
Show SMILES COc1ccc(\C=C\C(=O)N[C@H](C)C(=O)Nc2nnc(s2)-c2ccc(cc2)[N+]([O-])=O)cc1 |r|
Show InChI InChI=1S/C21H19N5O5S/c1-13(22-18(27)12-5-14-3-10-17(31-2)11-4-14)19(28)23-21-25-24-20(32-21)15-6-8-16(9-7-15)26(29)30/h3-13H,1-2H3,(H,22,27)(H,23,25,28)/b12-5+/t13-/m1/s1
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n/an/a 2.97E+5n/an/an/an/an/an/a



ShanDong University

Curated by ChEMBL


Assay Description
Inhibition of MMP2

Bioorg Med Chem 16: 6663-8 (2008)


Article DOI: 10.1016/j.bmc.2008.05.081
BindingDB Entry DOI: 10.7270/Q2RB74DK
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%