Affinity Data by PubMed id=18771255

PubMed code 18771255

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253794 (CHEMBL461432 \| Ethyl 5-amino-3-(3-chlorophenyl)-4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253793 (CHEMBL461431 \| Ethyl 5-Amino-4-oxo-3-phenyl-3,4-di...) Show SMILES CCOC(=O)c1nn(-c2ccccc2)c(=O)c2c(N)scc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253836 (CHEMBL462492 \| Ethyl 5-amino-4-oxo-3-(4-(trifluoro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253792 (CHEMBL443152 \| ethyl 5-amino-3-(4-tert-butylphenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.75E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253795 (CHEMBL461646 \| Ethyl 5-Amino-4-oxo-3-(3-(trifluoro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253835 (CHEMBL462281 \| Ethyl 3-(4-Acetoxyphenyl)-5-amino-4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253834 (CHEMBL447654 \| Ethyl 5-Amino-3-(4-nitrophenyl)-4-o...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253833 (CHEMBL517439 \| Ethyl 5-Amino-4-oxo-3-(4-(trifluoro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253870 (5-Amino-3,4-dihydro-3-(4-methoxyphenyl)-4-oxo-thie...) Show SMILES COc1ccc(cc1)-n1nc(C(O)=O)c2csc(N)c2c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50080550 ((2-Amino-4,5-dimethyl-thiophen-3-yl)-(3-trifluorom...) Show SMILES Cc1sc(N)c(C(=O)c2cccc(c2)C(F)(F)F)c1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253797 (CHEMBL460366 \| Ethyl 5-Amino-3-(4-methoxyphenyl)-4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253832 (CHEMBL448624 \| Ethyl 5-amino-3-(4-iodophenyl)-4-ox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253324 (5-amino-3-methyl-N2-phenylthiophene-2,4-dicarboxam...) Show SMILES Cc1c(sc(N)c1C(N)=O)C(=O)Nc1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.95E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253751 ((2-amino-4,5-dimethylthiophen-3-yl)(thiophen-2-yl)...) Show SMILES Cc1sc(N)c(C(=O)c2cccs2)c1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253796 (CHEMBL452468 \| Ethyl 5-Amino-3-(4-hydroxyphenyl)-4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253869 (5-Amino-3,4-dihydro-4-oxo-3-phenyl-thieno[3,4-d]py...) Show SMILES Nc1scc2c(nn(-c3ccccc3)c(=O)c12)C(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
Monash University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%