Affinity Data by PubMed id=18834110

PubMed code 18834110

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50274024 (3-(5-(3-bromobenzylidene)-4-oxo-2-thioxothiazolidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Genetica Molecolare Curated by ChEMBL					Assay Description Inhibition of ATPase activity in human recombinant DDX3 expressed in Escherichia coli by luciferase-based luminescence assay in presence of ATP				J Med Chem 51: 6635-8 (2008) Article DOI: 10.1021/jm8008844 BindingDB Entry DOI: 10.7270/Q2XD11J3
Istituto di Genetica Molecolare Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50274221 (5-amino-3-(1-cyano-2-(5-(3-nitrophenyl)furan-2-yl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Genetica Molecolare Curated by ChEMBL					Assay Description Inhibition of ATPase activity in human recombinant DDX3 expressed in Escherichia coli by luciferase-based luminescence assay in presence of ATP				J Med Chem 51: 6635-8 (2008) Article DOI: 10.1021/jm8008844 BindingDB Entry DOI: 10.7270/Q2XD11J3
Istituto di Genetica Molecolare Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50274022 (3-(5-(3-bromobenzylidene)-4-oxo-2-thioxothiazolidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Genetica Molecolare Curated by ChEMBL					Assay Description Inhibition of ATPase activity in human recombinant DDX3 expressed in Escherichia coli by luciferase-based luminescence assay in presence of ATP				J Med Chem 51: 6635-8 (2008) Article DOI: 10.1021/jm8008844 BindingDB Entry DOI: 10.7270/Q2XD11J3
Istituto di Genetica Molecolare Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50274025 (4-(5-(3-bromobenzylidene)-4-oxo-2-thioxothiazolidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Genetica Molecolare Curated by ChEMBL					Assay Description Inhibition of ATPase activity in human recombinant DDX3 expressed in Escherichia coli by luciferase-based luminescence assay in presence of ATP				J Med Chem 51: 6635-8 (2008) Article DOI: 10.1021/jm8008844 BindingDB Entry DOI: 10.7270/Q2XD11J3
Istituto di Genetica Molecolare Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50274184 (2-(3-(5-(3-bromobenzylidene)-4-oxo-2-thioxothiazol...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Genetica Molecolare Curated by ChEMBL					Assay Description Inhibition of ATPase activity in human recombinant DDX3 expressed in Escherichia coli by luciferase-based luminescence assay in presence of ATP				J Med Chem 51: 6635-8 (2008) Article DOI: 10.1021/jm8008844 BindingDB Entry DOI: 10.7270/Q2XD11J3
Istituto di Genetica Molecolare Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50274781 (3-(5-(2-methoxybenzylidene)-4-oxo-2-thioxothiazoli...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Genetica Molecolare Curated by ChEMBL					Assay Description Inhibition of ATPase activity in human recombinant DDX3 expressed in Escherichia coli by luciferase-based luminescence assay in presence of ATP				J Med Chem 51: 6635-8 (2008) Article DOI: 10.1021/jm8008844 BindingDB Entry DOI: 10.7270/Q2XD11J3
Istituto di Genetica Molecolare Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50274023 (3-(5-(3-bromobenzylidene)-4-oxo-2-thioxothiazolidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Genetica Molecolare Curated by ChEMBL					Assay Description Inhibition of ATPase activity in human recombinant DDX3 expressed in Escherichia coli by luciferase-based luminescence assay in presence of ATP				J Med Chem 51: 6635-8 (2008) Article DOI: 10.1021/jm8008844 BindingDB Entry DOI: 10.7270/Q2XD11J3
Istituto di Genetica Molecolare Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50274220 (5-amino-3-(1-cyano-2-(5-(2-nitrophenyl)furan-2-yl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Genetica Molecolare Curated by ChEMBL					Assay Description Inhibition of ATPase activity in human recombinant DDX3 expressed in Escherichia coli by luciferase-based luminescence assay in presence of ATP				J Med Chem 51: 6635-8 (2008) Article DOI: 10.1021/jm8008844 BindingDB Entry DOI: 10.7270/Q2XD11J3
Istituto di Genetica Molecolare Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50274222 (5-amino-3-(2-(5-(3-chlorophenyl)furan-2-yl)-1-cyan...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Genetica Molecolare Curated by ChEMBL					Assay Description Inhibition of ATPase activity in human recombinant DDX3 expressed in Escherichia coli by luciferase-based luminescence assay in presence of ATP				J Med Chem 51: 6635-8 (2008) Article DOI: 10.1021/jm8008844 BindingDB Entry DOI: 10.7270/Q2XD11J3
Istituto di Genetica Molecolare Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50274780 (4-(5-(3-bromobenzylidene)-4-oxo-2-thioxothiazolidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Genetica Molecolare Curated by ChEMBL					Assay Description Inhibition of ATPase activity in human recombinant DDX3 expressed in Escherichia coli by luciferase-based luminescence assay in presence of ATP				J Med Chem 51: 6635-8 (2008) Article DOI: 10.1021/jm8008844 BindingDB Entry DOI: 10.7270/Q2XD11J3
Istituto di Genetica Molecolare Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%