Affinity Data by PubMed id=19059777

PubMed code 19059777

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dihydrofolate reductase (Homo sapiens (Human))	BDBM50366327 (CHEMBL192037) Show SMILES CCCN(CCC)[C@H]1CCn2cccc2C1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of human DHFR				Bioorg Med Chem Lett 19: 418-23 (2008) Article DOI: 10.1016/j.bmcl.2008.11.054 BindingDB Entry DOI: 10.7270/Q2JS9RCZ
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Toxoplasma gondii)	BDBM50366327 (CHEMBL192037) Show SMILES CCCN(CCC)[C@H]1CCn2cccc2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of Toxoplasma gondii TS-DHFR				Bioorg Med Chem Lett 19: 418-23 (2008) Article DOI: 10.1016/j.bmcl.2008.11.054 BindingDB Entry DOI: 10.7270/Q2JS9RCZ
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidylate synthase (Homo sapiens (Human))	BDBM50366327 (CHEMBL192037) Show SMILES CCCN(CCC)[C@H]1CCn2cccc2C1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of human thymidylate synthase				Bioorg Med Chem Lett 19: 418-23 (2008) Article DOI: 10.1016/j.bmcl.2008.11.054 BindingDB Entry DOI: 10.7270/Q2JS9RCZ
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%