Affinity Data by PubMed id=19101144

PubMed code 19101144

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nischarin (RAT)	BDBM50016897 (2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	366	n/a	n/a	n/a	n/a	n/a	n/a
Gda£?sk University of Technology Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney by liquid scintillation counting				Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6
Gda£?sk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50256481 (([4(5)S]-4(5)-(2-aminoethyl)imidazoline) dihydrobr...) Show SMILES NCC[C@H]1CNC(N)=N1 \|r,c:7\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	477	n/a	n/a	n/a	n/a	n/a	n/a
Gda£?sk University of Technology Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney by liquid scintillation counting				Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6
Gda£?sk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50256484 ((R)-2-(4,5-dihydro-1H-imidazol-5-yl)ethanamine dih...) Show SMILES NCC[C@@H]1CNC=N1 \|r,c:6\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gda£?sk University of Technology Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney by liquid scintillation counting				Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6
Gda£?sk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM85213 (Agmatine \| CAS_306-60-5 \| CHEMBL58343 \| NSC_199 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gda£?sk University of Technology Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Wistar rat kidney by liquid scintillation counting				Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6
Gda£?sk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50256541 ((S)-5-(2-(dimethylamino)ethyl)-4,5-dihydro-1H-imid...) Show SMILES CN(C)CC[C@H]1CNC(N)=N1 \|r,c:9\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gda£?sk University of Technology Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney by liquid scintillation counting				Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6
Gda£?sk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50256542 ((S)-2-(4,5-dihydro-1H-imidazol-5-yl)-N,N-dimethyle...) Show SMILES CN(C)CC[C@H]1CNC=N1 \|r,c:8\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gda£?sk University of Technology Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney by liquid scintillation counting				Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6
Gda£?sk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50256482 ((R)-5-(2-aminoethyl)-4,5-dihydro-1H-imidazol-2-ami...) Show SMILES NCC[C@@H]1CNC(N)=N1 \|r,c:7\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gda£?sk University of Technology Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney by liquid scintillation counting				Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6
Gda£?sk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50256483 ((S)-2-(4,5-dihydro-1H-imidazol-5-yl)ethanamine dih...) Show SMILES NCC[C@H]1CNC=N1 \|r,c:6\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gda£?sk University of Technology Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney by liquid scintillation counting				Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6
Gda£?sk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50256485 ((S)-2-(2-methyl-4,5-dihydro-1H-imidazol-5-yl)ethan...) Show SMILES CC1=N[C@@H](CCN)CN1 \|r,t:1\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.15E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gda£?sk University of Technology Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney by liquid scintillation counting				Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6
Gda£?sk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50256540 ((S)-N-(2-(4,5-dihydro-1H-imidazol-5-yl)ethyl)aceta...) Show SMILES CC(=O)NCC[C@H]1CNC=N1 \|r,c:9\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.13E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gda£?sk University of Technology Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney by liquid scintillation counting				Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6
Gda£?sk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50256486 ((S)-N-(2-(2-amino-4,5-dihydro-1H-imidazol-5-yl)eth...) Show SMILES CC(=O)NCC[C@H]1CNC(N)=N1 \|r,c:10\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gda£?sk University of Technology Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney by liquid scintillation counting				Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6
Gda£?sk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50256487 ((R)-N-(2-(2-amino-4,5-dihydro-1H-imidazol-5-yl)eth...) Show SMILES CC(=O)NCC[C@@H]1CNC(N)=N1 \|r,c:10\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.83E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gda£?sk University of Technology Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney by liquid scintillation counting				Bioorg Med Chem Lett 19: 1009-11 (2009) Article DOI: 10.1016/j.bmcl.2008.11.055 BindingDB Entry DOI: 10.7270/Q2125SJ6
Gda£?sk University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%