Found 17 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50124303
(3-[16-carbamoyl-31-carbamoylmethyl-10-(2-carboxyet...)Show SMILES CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C Show InChI InChI=1S/C55H78N12O18S2/c1-27(2)20-36-51(81)64-37(21-29-6-10-31(68)11-7-29)52(82)61-34(15-17-45(75)76)49(79)65-39(23-41(56)70)54(84)67-46(28(3)4)55(85)58-24-42(71)59-35(18-19-86-5)50(80)63-38(22-30-8-12-32(69)13-9-30)53(83)66-40(47(57)77)25-87-26-43(72)60-33(48(78)62-36)14-16-44(73)74/h6-13,27-28,33-40,46,68-69H,14-26H2,1-5H3,(H2,56,70)(H2,57,77)(H,58,85)(H,59,71)(H,60,72)(H,61,82)(H,62,78)(H,63,80)(H,64,81)(H,65,79)(H,66,83)(H,67,84)(H,73,74)(H,75,76)/t33-,34-,35-,36-,37-,38-,39-,40-,46-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50378059
(CHEMBL1627251)Show SMILES CC(C)C1NC(=O)C(CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC1=O)C(N)=O Show InChI InChI=1S/C30H44N7O12PS/c1-16(2)24-28(43)34-21(25(32)40)14-51(48)15-23(39)33-19(12-17-6-8-18(9-7-17)49-50(45,46)47)27(42)37-30(10-4-3-5-11-30)29(44)35-20(13-22(31)38)26(41)36-24/h6-9,16,19-21,24H,3-5,10-15H2,1-2H3,(H2,31,38)(H2,32,40)(H,33,39)(H,34,43)(H,35,44)(H,36,41)(H,37,42)(H2,45,46,47) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.76E+3 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50294416
(4-{[(9S,15R,18S,21S)-15-carbamoyl-21-(carbamoylmet...)Show SMILES NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O |r| Show InChI InChI=1S/C36H45N8O11PS/c37-29(45)16-27-33(49)41-26(15-21-17-39-24-7-3-2-6-23(21)24)32(48)42-28(31(38)47)18-57-19-30(46)40-25(14-20-8-10-22(11-9-20)55-56(52,53)54)34(50)44-36(35(51)43-27)12-4-1-5-13-36/h2-3,6-11,17,25-28,39H,1,4-5,12-16,18-19H2,(H2,37,45)(H2,38,47)(H,40,46)(H,41,49)(H,42,48)(H,43,51)(H,44,50)(H2,52,53,54)/t25-,26-,27-,28-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50378057
(CHEMBL1627267)Show SMILES NC(=O)CC1NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC(=O)C(Cc2c[nH]c3ccccc23)NC1=O)C(N)=O Show InChI InChI=1S/C36H45N8O12PS/c37-29(45)16-27-33(49)41-26(15-21-17-39-24-7-3-2-6-23(21)24)32(48)42-28(31(38)47)18-58(55)19-30(46)40-25(14-20-8-10-22(11-9-20)56-57(52,53)54)34(50)44-36(35(51)43-27)12-4-1-5-13-36/h2-3,6-11,17,25-28,39H,1,4-5,12-16,18-19H2,(H2,37,45)(H2,38,47)(H,40,46)(H,41,49)(H,42,48)(H,43,51)(H,44,50)(H2,52,53,54) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.29E+3 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50378058
(CHEMBL1627247)Show SMILES NC(=O)CC1NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC(=O)C(Cc2ccc(O)cc2)NC1=O)C(N)=O Show InChI InChI=1S/C34H44N7O13PS/c35-27(43)16-25-31(47)38-23(14-19-4-8-21(42)9-5-19)30(46)39-26(29(36)45)17-56(53)18-28(44)37-24(15-20-6-10-22(11-7-20)54-55(50,51)52)32(48)41-34(33(49)40-25)12-2-1-3-13-34/h4-11,23-26,42H,1-3,12-18H2,(H2,35,43)(H2,36,45)(H,37,44)(H,38,47)(H,39,46)(H,40,49)(H,41,48)(H2,50,51,52) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.36E+3 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50378059
(CHEMBL1627251)Show SMILES CC(C)C1NC(=O)C(CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC1=O)C(N)=O Show InChI InChI=1S/C30H44N7O12PS/c1-16(2)24-28(43)34-21(25(32)40)14-51(48)15-23(39)33-19(12-17-6-8-18(9-7-17)49-50(45,46)47)27(42)37-30(10-4-3-5-11-30)29(44)35-20(13-22(31)38)26(41)36-24/h6-9,16,19-21,24H,3-5,10-15H2,1-2H3,(H2,31,38)(H2,32,40)(H,33,39)(H,34,43)(H,35,44)(H,36,41)(H,37,42)(H2,45,46,47) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.56E+3 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50294417
(4-{[(9S,15R,18S,21S)-15-carbamoyl-21-(carbamoylmet...)Show SMILES NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O |r| Show InChI InChI=1S/C34H44N7O12PS/c35-27(43)16-25-31(47)38-23(14-19-4-8-21(42)9-5-19)30(46)39-26(29(36)45)17-55-18-28(44)37-24(15-20-6-10-22(11-7-20)53-54(50,51)52)32(48)41-34(33(49)40-25)12-2-1-3-13-34/h4-11,23-26,42H,1-3,12-18H2,(H2,35,43)(H2,36,45)(H,37,44)(H,38,47)(H,39,46)(H,40,49)(H,41,48)(H2,50,51,52)/t23-,24-,25-,26-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50294420
(4-[(9S,12S,19S,22S)-12-amino-22-(carbamoylmethyl)-...)Show SMILES CC(C)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCCNC1=O)c1ccc(OP(O)(O)=O)cc1 |r| Show InChI InChI=1S/C30H46N7O10P/c1-17(2)23-27(41)33-15-7-4-8-20(31)25(39)36-24(18-9-11-19(12-10-18)47-48(44,45)46)28(42)37-30(13-5-3-6-14-30)29(43)34-21(16-22(32)38)26(40)35-23/h9-12,17,20-21,23-24H,3-8,13-16,31H2,1-2H3,(H2,32,38)(H,33,41)(H,34,43)(H,35,40)(H,36,39)(H,37,42)(H2,44,45,46)/t20-,21-,23-,24-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.55E+3 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50124303
(3-[16-carbamoyl-31-carbamoylmethyl-10-(2-carboxyet...)Show SMILES CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C Show InChI InChI=1S/C55H78N12O18S2/c1-27(2)20-36-51(81)64-37(21-29-6-10-31(68)11-7-29)52(82)61-34(15-17-45(75)76)49(79)65-39(23-41(56)70)54(84)67-46(28(3)4)55(85)58-24-42(71)59-35(18-19-86-5)50(80)63-38(22-30-8-12-32(69)13-9-30)53(83)66-40(47(57)77)25-87-26-43(72)60-33(48(78)62-36)14-16-44(73)74/h6-13,27-28,33-40,46,68-69H,14-26H2,1-5H3,(H2,56,70)(H2,57,77)(H,58,85)(H,59,71)(H,60,72)(H,61,82)(H,62,78)(H,63,80)(H,64,81)(H,65,79)(H,66,83)(H,67,84)(H,73,74)(H,75,76)/t33-,34-,35-,36-,37-,38-,39-,40-,46-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50378058
(CHEMBL1627247)Show SMILES NC(=O)CC1NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC(=O)C(Cc2ccc(O)cc2)NC1=O)C(N)=O Show InChI InChI=1S/C34H44N7O13PS/c35-27(43)16-25-31(47)38-23(14-19-4-8-21(42)9-5-19)30(46)39-26(29(36)45)17-56(53)18-28(44)37-24(15-20-6-10-22(11-7-20)54-55(50,51)52)32(48)41-34(33(49)40-25)12-2-1-3-13-34/h4-11,23-26,42H,1-3,12-18H2,(H2,35,43)(H2,36,45)(H,37,44)(H,38,47)(H,39,46)(H,40,49)(H,41,48)(H2,50,51,52) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.72E+3 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50294418
(4-{[(9S,15R,18S,21S)-15-carbamoyl-21-(carbamoylmet...)Show SMILES CC(C)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC1=O)C(N)=O |r| Show InChI InChI=1S/C30H44N7O11PS/c1-16(2)24-28(43)34-21(25(32)40)14-50-15-23(39)33-19(12-17-6-8-18(9-7-17)48-49(45,46)47)27(42)37-30(10-4-3-5-11-30)29(44)35-20(13-22(31)38)26(41)36-24/h6-9,16,19-21,24H,3-5,10-15H2,1-2H3,(H2,31,38)(H2,32,40)(H,33,39)(H,34,43)(H,35,44)(H,36,41)(H,37,42)(H2,45,46,47)/t19-,20-,21-,24-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50378056
(CHEMBL1627249)Show SMILES NC(=O)CC1NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC(=O)C(Cc2ccc3ccccc3c2)NC1=O)C(N)=O Show InChI InChI=1S/C38H46N7O12PS/c39-31(46)19-29-35(50)42-27(18-23-8-11-24-6-2-3-7-25(24)16-23)34(49)43-30(33(40)48)20-59(56)21-32(47)41-28(17-22-9-12-26(13-10-22)57-58(53,54)55)36(51)45-38(37(52)44-29)14-4-1-5-15-38/h2-3,6-13,16,27-30H,1,4-5,14-15,17-21H2,(H2,39,46)(H2,40,48)(H,41,47)(H,42,50)(H,43,49)(H,44,52)(H,45,51)(H2,53,54,55) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50378057
(CHEMBL1627267)Show SMILES NC(=O)CC1NC(=O)C2(CCCCC2)NC(=O)C(Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CS(=O)CC(NC(=O)C(Cc2c[nH]c3ccccc23)NC1=O)C(N)=O Show InChI InChI=1S/C36H45N8O12PS/c37-29(45)16-27-33(49)41-26(15-21-17-39-24-7-3-2-6-23(21)24)32(48)42-28(31(38)47)18-58(55)19-30(46)40-25(14-20-8-10-22(11-9-20)56-57(52,53)54)34(50)44-36(35(51)43-27)12-4-1-5-13-36/h2-3,6-11,17,25-28,39H,1,4-5,12-16,18-19H2,(H2,37,45)(H2,38,47)(H,40,46)(H,41,49)(H,42,48)(H,43,51)(H,44,50)(H2,52,53,54) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.14E+3 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50294415
(4-{[(9S,15R,18S,21S)-15-carbamoyl-21-(carbamoylmet...)Show SMILES NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc3ccccc3c2)NC1=O)C(N)=O |r| Show InChI InChI=1S/C38H46N7O11PS/c39-31(46)19-29-35(50)42-27(18-23-8-11-24-6-2-3-7-25(24)16-23)34(49)43-30(33(40)48)20-58-21-32(47)41-28(17-22-9-12-26(13-10-22)56-57(53,54)55)36(51)45-38(37(52)44-29)14-4-1-5-15-38/h2-3,6-13,16,27-30H,1,4-5,14-15,17-21H2,(H2,39,46)(H2,40,48)(H,41,47)(H,42,50)(H,43,49)(H,44,52)(H,45,51)(H2,53,54,55)/t27-,28-,29-,30-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.71E+3 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50294419
(3-[(5S,8S,11S,14S,17R)-17-carbamoyl-11-(carbamoylm...)Show SMILES CC(C)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC1=O)C(N)=O |r| Show InChI InChI=1S/C28H40N7O13PS/c1-13(2)23-28(44)34-19(24(30)40)11-50-12-21(37)31-17(9-14-3-5-15(6-4-14)48-49(45,46)47)26(42)32-16(7-8-22(38)39)25(41)33-18(10-20(29)36)27(43)35-23/h3-6,13,16-19,23H,7-12H2,1-2H3,(H2,29,36)(H2,30,40)(H,31,37)(H,32,42)(H,33,41)(H,34,44)(H,35,43)(H,38,39)(H2,45,46,47)/t16-,17-,18-,19-,23-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50294421
(4-{[(9S,15R,18S,21S)-15-carbamoyl-21-(carbamoylmet...)Show SMILES CC(C)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCNC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC1=O)C(N)=O |r| Show InChI InChI=1S/C29H43N8O11PS/c1-15(2)23-27(43)34-20(24(31)40)12-50-13-22(39)33-18(10-16-4-6-17(7-5-16)48-49(45,46)47)26(42)37-29(8-3-9-32-14-29)28(44)35-19(11-21(30)38)25(41)36-23/h4-7,15,18-20,23,32H,3,8-14H2,1-2H3,(H2,30,38)(H2,31,40)(H,33,39)(H,34,43)(H,35,44)(H,36,41)(H,37,42)(H2,45,46,47)/t18-,19-,20-,23-,29?/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 359 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
Growth factor receptor-bound protein 2
(Homo sapiens (Human)) | BDBM50294422
(4-{[(9S,15R,18S,21S)-15-carbamoyl-21-(carbamoylmet...)Show SMILES CC(C)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCS(=O)(=O)CC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CSC[C@H](NC1=O)C(N)=O |r| Show InChI InChI=1S/C29H42N7O13PS2/c1-15(2)23-27(42)33-20(24(31)39)13-51-14-22(38)32-18(11-16-3-5-17(6-4-16)49-50(44,45)46)26(41)36-29(7-9-52(47,48)10-8-29)28(43)34-19(12-21(30)37)25(40)35-23/h3-6,15,18-20,23H,7-14H2,1-2H3,(H2,30,37)(H2,31,39)(H,32,38)(H,33,42)(H,34,43)(H,35,40)(H,36,41)(H2,44,45,46)/t18-,19-,20-,23-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assay |
Bioorg Med Chem Lett 19: 2693-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.03.134
BindingDB Entry DOI: 10.7270/Q2862HC2 |
More data for this
Ligand-Target Pair | |
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