Affinity Data by PubMed id=19394229

PubMed code 19394229

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50259542 (2-(3-Trifluoromethylphenyl)-4(5)-(3-trifluoromethy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50259388 (2-(4-Chlorophenyl)-4(5)-phenylimidazole \| CHEMBL50...) Show SMILES Clc1ccc(cc1)-c1nc(c[nH]1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50259490 (2-Phenyl-4(5)-(4-trifluoromethylphenyl)imidazole \|...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50259541 (2-(4-Nitrophenyl)-4(5)-(3-trifluoromethylphenyl)-i...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50145044 (2-Phenyl-4(5)-(3-trifluoromethylphenyl)imidazole \|...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50133778 (2,4(5)-Diphenylimidazole \| 2,4-diphenyl-1H-imidazo...) Show SMILES c1[nH]c(nc1-c1ccccc1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50031299 (6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamin...) Show SMILES Nc1nnc(c(N)n1)-c1cccc(Cl)c1Cl Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50259540 (2-(4-Chlorophenyl)-4(5)-(3-trifluoromethylphenyl)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50003655 (Phenytoin) Show SMILES O=C1NC(=O)C(N1)(c1ccccc1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%