Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C-X-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50335557 (CHEMBL1652605 | N,N-dipropyl-N'-[4-({[(1H-imidazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Infectious Diseases Curated by ChEMBL | Assay Description Displacement of [125I]SDF-1alpha form CXCR4 expressed in CHO cells by scintillation counting | Antimicrob Agents Chemother 53: 2940-8 (2009) Article DOI: 10.1128/AAC.01727-08 BindingDB Entry DOI: 10.7270/Q2GF0TR7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50335557 (CHEMBL1652605 | N,N-dipropyl-N'-[4-({[(1H-imidazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Infectious Diseases Curated by ChEMBL | Assay Description Inhibition of Mab 12G5 binding to wild type CXCR4 expressed in HEK293 cells | Antimicrob Agents Chemother 53: 2940-8 (2009) Article DOI: 10.1128/AAC.01727-08 BindingDB Entry DOI: 10.7270/Q2GF0TR7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50035696 (1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 289 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Infectious Diseases Curated by ChEMBL | Assay Description Inhibition of Mab 12G5 binding to wild type CXCR4 expressed in HEK293 cells | Antimicrob Agents Chemother 53: 2940-8 (2009) Article DOI: 10.1128/AAC.01727-08 BindingDB Entry DOI: 10.7270/Q2GF0TR7 | |||||||||||
More data for this Ligand-Target Pair |