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PubMed code 19505824

Compile data set for download or QSAR
Found 36 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296089
PNG
(2-(2-(5-(3-(2-(6,7-difluoroquinolin-2-yl)vinyl)ben...)
Show SMILES OC(=O)c1ccccc1OCCN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3cc(F)c(F)cc3n2)c1
Show InChI InChI=1S/C38H31F2N3O3/c39-32-21-27-13-15-28(41-34(27)22-33(32)40)14-12-25-6-5-7-26(20-25)23-43-35-10-3-1-8-29(35)31-24-42(17-16-36(31)43)18-19-46-37-11-4-2-9-30(37)38(44)45/h1-15,20-22H,16-19,23-24H2,(H,44,45)/b14-12+
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n/an/a 0.910n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296106
PNG
(3-(5-(3-(2-(6,7-difluoroquinolin-2-yl)vinyl)benzyl...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3cc(F)c(F)cc3n2)c1
Show InChI InChI=1S/C32H27F2N3O2/c33-27-17-23-9-11-24(35-29(23)18-28(27)34)10-8-21-4-3-5-22(16-21)19-37-30-7-2-1-6-25(30)26-20-36(14-12-31(26)37)15-13-32(38)39/h1-11,16-18H,12-15,19-20H2,(H,38,39)/b10-8+
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n/an/a 1n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296115
PNG
(3-(5-(3-(2-(6,7-difluoroquinolin-2-yl)vinyl)benzyl...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1c(F)cccc1n2Cc1cccc(\C=C\c2ccc3cc(F)c(F)cc3n2)c1
Show InChI InChI=1S/C32H26F3N3O2/c33-25-5-2-6-30-32(25)24-19-37(14-12-31(39)40)13-11-29(24)38(30)18-21-4-1-3-20(15-21)7-9-23-10-8-22-16-26(34)27(35)17-28(22)36-23/h1-10,15-17H,11-14,18-19H2,(H,39,40)/b9-7+
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n/an/a 1.20n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296095
PNG
(2-(2-(1H-tetrazol-5-yl)ethyl)-9-(3-(2-(7-chloroqui...)
Show SMILES Clc1ccc2ccc(C=Cc3cccc(Cn4c5CN(CCc6nnn[nH]6)CCc5c5ccccc45)c3)nc2c1 |w:9.9|
Show InChI InChI=1S/C32H28ClN7/c33-25-11-9-24-10-13-26(34-29(24)19-25)12-8-22-4-3-5-23(18-22)20-40-30-7-2-1-6-27(30)28-14-16-39(21-31(28)40)17-15-32-35-37-38-36-32/h1-13,18-19H,14-17,20-21H2,(H,35,36,37,38)
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n/an/a 1.20n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296092
PNG
(3-(5-(3-((7-chloroquinolin-2-yl)ethynyl)benzyl)-3,...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1ccccc1n2Cc1cccc(c1)C#Cc1ccc2ccc(Cl)cc2n1
Show InChI InChI=1S/C32H26ClN3O2/c33-25-11-9-24-10-13-26(34-29(24)19-25)12-8-22-4-3-5-23(18-22)20-36-30-7-2-1-6-27(30)28-21-35(16-14-31(28)36)17-15-32(37)38/h1-7,9-11,13,18-19H,14-17,20-21H2,(H,37,38)
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n/an/a 1.30n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296105
PNG
(3-(5-(3-(2-(7-chloro-6-fluoroquinolin-2-yl)vinyl)b...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3cc(F)c(Cl)cc3n2)c1
Show InChI InChI=1S/C32H27ClFN3O2/c33-27-18-29-23(17-28(27)34)9-11-24(35-29)10-8-21-4-3-5-22(16-21)19-37-30-7-2-1-6-25(30)26-20-36(14-12-31(26)37)15-13-32(38)39/h1-11,16-18H,12-15,19-20H2,(H,38,39)/b10-8+
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n/an/a 1.70n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296114
PNG
(3-(5-(3-(2-(6,7-difluoroquinolin-2-yl)vinyl)benzyl...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1cc(F)ccc1n2Cc1cccc(\C=C\c2ccc3cc(F)c(F)cc3n2)c1
Show InChI InChI=1S/C32H26F3N3O2/c33-23-6-9-30-25(16-23)26-19-37(13-11-32(39)40)12-10-31(26)38(30)18-21-3-1-2-20(14-21)4-7-24-8-5-22-15-27(34)28(35)17-29(22)36-24/h1-9,14-17H,10-13,18-19H2,(H,39,40)/b7-4+
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n/an/a 2.5n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296088
PNG
(4-((5-(3-(2-(6,7-difluoroquinolin-2-yl)vinyl)benzy...)
Show SMILES OC(=O)c1ccc(CN2CCc3c(C2)c2ccccc2n3Cc2cccc(\C=C\c3ccc4cc(F)c(F)cc4n3)c2)cc1
Show InChI InChI=1S/C37H29F2N3O2/c38-32-19-28-13-15-29(40-34(28)20-33(32)39)14-10-24-4-3-5-26(18-24)22-42-35-7-2-1-6-30(35)31-23-41(17-16-36(31)42)21-25-8-11-27(12-9-25)37(43)44/h1-15,18-20H,16-17,21-23H2,(H,43,44)/b14-10+
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n/an/a 3n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296085
PNG
(2-(1-((5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl...)
Show SMILES OC(=O)CC1(CN2CCc3c(C2)c2ccccc2n3Cc2cccc(\C=C\c3ccc4ccc(Cl)cc4n3)c2)CC1
Show InChI InChI=1S/C35H32ClN3O2/c36-27-11-9-26-10-13-28(37-31(26)19-27)12-8-24-4-3-5-25(18-24)21-39-32-7-2-1-6-29(32)30-22-38(17-14-33(30)39)23-35(15-16-35)20-34(40)41/h1-13,18-19H,14-17,20-23H2,(H,40,41)/b12-8+
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n/an/a 3.20n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296102
PNG
(4-(1-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-2-...)
Show SMILES Cc1c(CCCC(O)=O)c2ccccc2n1Cc1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
Show InChI InChI=1S/C31H27ClN2O2/c1-21-27(9-5-11-31(35)36)28-8-2-3-10-30(28)34(21)20-23-7-4-6-22(18-23)12-16-26-17-14-24-13-15-25(32)19-29(24)33-26/h2-4,6-8,10,12-19H,5,9,11,20H2,1H3,(H,35,36)/b16-12+
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n/an/a 3.40n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296103
PNG
(3-(5-(3-(2-(7-fluoroquinolin-2-yl)vinyl)benzyl)-3,...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3ccc(F)cc3n2)c1
Show InChI InChI=1S/C32H28FN3O2/c33-25-11-9-24-10-13-26(34-29(24)19-25)12-8-22-4-3-5-23(18-22)20-36-30-7-2-1-6-27(30)28-21-35(16-14-31(28)36)17-15-32(37)38/h1-13,18-19H,14-17,20-21H2,(H,37,38)/b12-8+
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n/an/a 3.40n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296087
PNG
(4-(5-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)benzyl...)
Show SMILES OC(=O)\C=C\CN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
Show InChI InChI=1S/C33H28ClN3O2/c34-26-13-11-25-12-15-27(35-30(25)20-26)14-10-23-5-3-6-24(19-23)21-37-31-8-2-1-7-28(31)29-22-36(18-16-32(29)37)17-4-9-33(38)39/h1-15,19-20H,16-18,21-22H2,(H,38,39)/b9-4+,14-10+
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n/an/a 4.10n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296101
PNG
(4-(1-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-1H...)
Show SMILES OC(=O)CCCc1cn(Cc2cccc(\C=C\c3ccc4ccc(Cl)cc4n3)c2)c2ccccc12
Show InChI InChI=1S/C30H25ClN2O2/c31-25-14-12-23-13-16-26(32-28(23)18-25)15-11-21-5-3-6-22(17-21)19-33-20-24(7-4-10-30(34)35)27-8-1-2-9-29(27)33/h1-3,5-6,8-9,11-18,20H,4,7,10,19H2,(H,34,35)/b15-11+
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n/an/a 4.40n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296113
PNG
(3-(5-(3-(2-(6,7-difluoroquinolin-2-yl)vinyl)benzyl...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1ccc(F)cc1n2Cc1cccc(\C=C\c2ccc3cc(F)c(F)cc3n2)c1
Show InChI InChI=1S/C32H26F3N3O2/c33-23-6-9-25-26-19-37(13-11-32(39)40)12-10-30(26)38(31(25)16-23)18-21-3-1-2-20(14-21)4-7-24-8-5-22-15-27(34)28(35)17-29(22)36-24/h1-9,14-17H,10-13,18-19H2,(H,39,40)/b7-4+
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n/an/a 4.5n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296099
PNG
(3-(9-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-9H...)
Show SMILES OC(=O)CCc1ccc2n(Cc3cccc(\C=C\c4ccc5ccc(Cl)cc5n4)c3)c3ccccc3c2c1
Show InChI InChI=1S/C33H25ClN2O2/c34-26-13-11-25-12-15-27(35-30(25)20-26)14-8-22-4-3-5-24(18-22)21-36-31-7-2-1-6-28(31)29-19-23(9-16-32(29)36)10-17-33(37)38/h1-9,11-16,18-20H,10,17,21H2,(H,37,38)/b14-8+
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n/an/a 4.80n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296100
PNG
(2-(9-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-2,...)
Show SMILES OC(=O)CC1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
Show InChI InChI=1S/C32H27ClN2O2/c33-25-12-10-24-11-14-26(34-29(24)19-25)13-8-21-4-3-5-23(16-21)20-35-30-7-2-1-6-27(30)28-17-22(18-32(36)37)9-15-31(28)35/h1-8,10-14,16,19,22H,9,15,17-18,20H2,(H,36,37)/b13-8+
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n/an/a 4.90n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296112
PNG
(3-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-8-...)
Show SMILES COc1ccc2n(Cc3cccc(\C=C\c4ccc5ccc(Cl)cc5n4)c3)c3CCN(CCC(O)=O)Cc3c2c1
Show InChI InChI=1S/C33H30ClN3O3/c1-40-27-11-12-31-28(19-27)29-21-36(16-14-33(38)39)15-13-32(29)37(31)20-23-4-2-3-22(17-23)5-9-26-10-7-24-6-8-25(34)18-30(24)35-26/h2-12,17-19H,13-16,20-21H2,1H3,(H,38,39)/b9-5+
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n/an/a 7.5n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296097
PNG
(3-((2-(1-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl...)
Show SMILES CN(CCC(O)=O)CCc1cn(Cc2cccc(\C=C\c3ccc4ccc(Cl)cc4n3)c2)c2ccccc12
Show InChI InChI=1S/C32H30ClN3O2/c1-35(18-16-32(37)38)17-15-26-22-36(31-8-3-2-7-29(26)31)21-24-6-4-5-23(19-24)9-13-28-14-11-25-10-12-27(33)20-30(25)34-28/h2-14,19-20,22H,15-18,21H2,1H3,(H,37,38)/b13-9+
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n/an/a 9.30n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296096
PNG
(3-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,...)
Show SMILES OC(=O)CCN1CCC2C(C1)c1ccccc1N2Cc1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
Show InChI InChI=1S/C32H30ClN3O2/c33-25-11-9-24-10-13-26(34-29(24)19-25)12-8-22-4-3-5-23(18-22)20-36-30-7-2-1-6-27(30)28-21-35(16-14-31(28)36)17-15-32(37)38/h1-13,18-19,28,31H,14-17,20-21H2,(H,37,38)/b12-8+
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n/an/a 12n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296116
PNG
(3-(5-((2-(7-chloroquinolin-2-yl)benzofuran-5-yl)me...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1ccccc1n2Cc1ccc2oc(cc2c1)-c1ccc2ccc(Cl)cc2n1
Show InChI InChI=1S/C32H26ClN3O3/c33-23-8-6-21-7-9-26(34-27(21)17-23)31-16-22-15-20(5-10-30(22)39-31)18-36-28-4-2-1-3-24(28)25-19-35(13-11-29(25)36)14-12-32(37)38/h1-10,15-17H,11-14,18-19H2,(H,37,38)
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n/an/a 14n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296094
PNG
(4-(9-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-4,...)
Show SMILES OC(=O)CCCN1CCC2C(C1)N(Cc1cccc(\C=C\c3ccc4ccc(Cl)cc4n3)c1)c1ccccc21
Show InChI InChI=1S/C33H32ClN3O2/c34-26-13-11-25-12-15-27(35-30(25)20-26)14-10-23-5-3-6-24(19-23)21-37-31-8-2-1-7-28(31)29-16-18-36(22-32(29)37)17-4-9-33(38)39/h1-3,5-8,10-15,19-20,29,32H,4,9,16-18,21-22H2,(H,38,39)/b14-10+
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n/an/a 15n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296081
PNG
(3-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
Show InChI InChI=1S/C32H28ClN3O2/c33-25-11-9-24-10-13-26(34-29(24)19-25)12-8-22-4-3-5-23(18-22)20-36-30-7-2-1-6-27(30)28-21-35(16-14-31(28)36)17-15-32(37)38/h1-13,18-19H,14-17,20-21H2,(H,37,38)/b12-8+
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n/an/a 16n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296111
PNG
(3-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-7-...)
Show SMILES COc1ccc2c3CN(CCC(O)=O)CCc3n(Cc3cccc(\C=C\c4ccc5ccc(Cl)cc5n4)c3)c2c1
Show InChI InChI=1S/C33H30ClN3O3/c1-40-27-11-12-28-29-21-36(16-14-33(38)39)15-13-31(29)37(32(28)19-27)20-23-4-2-3-22(17-23)5-9-26-10-7-24-6-8-25(34)18-30(24)35-26/h2-12,17-19H,13-16,20-21H2,1H3,(H,38,39)/b9-5+
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n/an/a 16n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296084
PNG
(5-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,...)
Show SMILES OC(=O)CCCCN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
Show InChI InChI=1S/C34H32ClN3O2/c35-27-14-12-26-13-16-28(36-31(26)21-27)15-11-24-6-5-7-25(20-24)22-38-32-9-2-1-8-29(32)30-23-37(19-17-33(30)38)18-4-3-10-34(39)40/h1-2,5-9,11-16,20-21H,3-4,10,17-19,22-23H2,(H,39,40)/b15-11+
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n/an/a 16n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296082
PNG
(2-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,...)
Show SMILES OC(=O)CN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
Show InChI InChI=1S/C31H26ClN3O2/c32-24-11-9-23-10-13-25(33-28(23)17-24)12-8-21-4-3-5-22(16-21)18-35-29-7-2-1-6-26(29)27-19-34(20-31(36)37)15-14-30(27)35/h1-13,16-17H,14-15,18-20H2,(H,36,37)/b12-8+
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n/an/a 17n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296093
PNG
(3-(9-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-4,...)
Show SMILES OC(=O)CCN1CCC2C(C1)N(Cc1cccc(\C=C\c3ccc4ccc(Cl)cc4n3)c1)c1ccccc21
Show InChI InChI=1S/C32H30ClN3O2/c33-25-11-9-24-10-13-26(34-29(24)19-25)12-8-22-4-3-5-23(18-22)20-36-30-7-2-1-6-27(30)28-14-16-35(21-31(28)36)17-15-32(37)38/h1-13,18-19,28,31H,14-17,20-21H2,(H,37,38)/b12-8+
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n/an/a 20n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296104
PNG
(3-(5-(3-(2-(6,7-dichloroquinolin-2-yl)vinyl)benzyl...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3cc(Cl)c(Cl)cc3n2)c1
Show InChI InChI=1S/C32H27Cl2N3O2/c33-27-17-23-9-11-24(35-29(23)18-28(27)34)10-8-21-4-3-5-22(16-21)19-37-30-7-2-1-6-25(30)26-20-36(14-12-31(26)37)15-13-32(38)39/h1-11,16-18H,12-15,19-20H2,(H,38,39)/b10-8+
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n/an/a 21n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296091
PNG
(3-(5-(3-(2-(7-chloroquinolin-2-yl)ethyl)benzyl)-3,...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1ccccc1n2Cc1cccc(CCc2ccc3ccc(Cl)cc3n2)c1
Show InChI InChI=1S/C32H30ClN3O2/c33-25-11-9-24-10-13-26(34-29(24)19-25)12-8-22-4-3-5-23(18-22)20-36-30-7-2-1-6-27(30)28-21-35(16-14-31(28)36)17-15-32(37)38/h1-7,9-11,13,18-19H,8,12,14-17,20-21H2,(H,37,38)
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n/an/a 25n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296086
PNG
(3-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,...)
Show SMILES OC(=O)CC(=O)N1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
Show InChI InChI=1S/C32H26ClN3O3/c33-24-11-9-23-10-13-25(34-28(23)17-24)12-8-21-4-3-5-22(16-21)19-36-29-7-2-1-6-26(29)27-20-35(15-14-30(27)36)31(37)18-32(38)39/h1-13,16-17H,14-15,18-20H2,(H,38,39)/b12-8+
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n/an/a 26n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296083
PNG
(4-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,...)
Show SMILES OC(=O)CCCN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
Show InChI InChI=1S/C33H30ClN3O2/c34-26-13-11-25-12-15-27(35-30(25)20-26)14-10-23-5-3-6-24(19-23)21-37-31-8-2-1-7-28(31)29-22-36(18-16-32(29)37)17-4-9-33(38)39/h1-3,5-8,10-15,19-20H,4,9,16-18,21-22H2,(H,38,39)/b14-10+
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n/an/a 30n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296107
PNG
(3-(5-(3-(2-(4-tert-butylthiazol-2-yl)vinyl)benzyl)...)
Show SMILES CC(C)(C)c1csc(\C=C\c2cccc(Cn3c4CCN(CCC(O)=O)Cc4c4ccccc34)c2)n1
Show InChI InChI=1S/C30H33N3O2S/c1-30(2,3)27-20-36-28(31-27)12-11-21-7-6-8-22(17-21)18-33-25-10-5-4-9-23(25)24-19-32(15-13-26(24)33)16-14-29(34)35/h4-12,17,20H,13-16,18-19H2,1-3H3,(H,34,35)/b12-11+
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n/an/a 37n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296090
PNG
(3-(5-(3-((7-chloroquinolin-2-yl)methoxy)benzyl)-3,...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1ccccc1n2Cc1cccc(OCc2ccc3ccc(Cl)cc3n2)c1
Show InChI InChI=1S/C31H28ClN3O3/c32-23-10-8-22-9-11-24(33-28(22)17-23)20-38-25-5-3-4-21(16-25)18-35-29-7-2-1-6-26(29)27-19-34(14-12-30(27)35)15-13-31(36)37/h1-11,16-17H,12-15,18-20H2,(H,36,37)
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n/an/a 42n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296109
PNG
(3-(5-(3-(2-(2,3-dichlorothieno[3,2-b]pyridin-5-yl)...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3sc(Cl)c(Cl)c3n2)c1
Show InChI InChI=1S/C30H25Cl2N3O2S/c31-28-29-26(38-30(28)32)11-10-21(33-29)9-8-19-4-3-5-20(16-19)17-35-24-7-2-1-6-22(24)23-18-34(14-12-25(23)35)15-13-27(36)37/h1-11,16H,12-15,17-18H2,(H,36,37)/b9-8+
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n/an/a 50n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296098
PNG
(3-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-...)
Show SMILES CN(CCC(O)=O)Cc1cn(Cc2cccc(\C=C\c3ccc4ccc(Cl)cc4n3)c2)c2ccccc12
Show InChI InChI=1S/C31H28ClN3O2/c1-34(16-15-31(36)37)20-25-21-35(30-8-3-2-7-28(25)30)19-23-6-4-5-22(17-23)9-13-27-14-11-24-10-12-26(32)18-29(24)33-27/h2-14,17-18,21H,15-16,19-20H2,1H3,(H,36,37)/b13-9+
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n/an/a 61n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296108
PNG
(3-(5-(3-(2-(5-chlorobenzo[d]thiazol-2-yl)vinyl)ben...)
Show SMILES OC(=O)CCN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2nc3cc(Cl)ccc3s2)c1
Show InChI InChI=1S/C30H26ClN3O2S/c31-22-9-10-28-25(17-22)32-29(37-28)11-8-20-4-3-5-21(16-20)18-34-26-7-2-1-6-23(26)24-19-33(14-12-27(24)34)15-13-30(35)36/h1-11,16-17H,12-15,18-19H2,(H,35,36)/b11-8+
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n/an/a 112n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296110
PNG
(3-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-6-...)
Show SMILES CCOc1cccc2c3CN(CCC(O)=O)CCc3n(Cc3cccc(\C=C\c4ccc5ccc(Cl)cc5n4)c3)c12
Show InChI InChI=1S/C34H32ClN3O3/c1-2-41-32-8-4-7-28-29-22-37(18-16-33(39)40)17-15-31(29)38(34(28)32)21-24-6-3-5-23(19-24)9-13-27-14-11-25-10-12-26(35)20-30(25)36-27/h3-14,19-20H,2,15-18,21-22H2,1H3,(H,39,40)/b13-9+
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n/an/a 150n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%