BindingDB logo
myBDB logout

PubMed code 19540762

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))
BDBM50298707
PNG
(1-Benzyl-6-chloro-7-hydroxy-1,2,3,4-tetrahydroisoq...)
Show SMILES Oc1cc2C(Cc3ccccc3)NCCc2cc1Cl
Show InChI InChI=1S/C16H16ClNO/c17-14-9-12-6-7-18-15(13(12)10-16(14)19)8-11-4-2-1-3-5-11/h1-5,9-10,15,18-19H,6-8H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
66n/an/an/an/an/an/an/an/a



Universidad de Valencia

Curated by ChEMBL


Assay Description
Displacement of [3H]raclopride from dopamine D2 receptor in Wistar rat striatal membrane by liquid scintillation counting


Bioorg Med Chem 17: 4968-80 (2009)


Article DOI: 10.1016/j.bmc.2009.05.079
BindingDB Entry DOI: 10.7270/Q26D5T2B
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))
BDBM50298706
PNG
(1-Butyl-6-chloro-7-hydroxy-1,2,3,4-tetrahydroisoqu...)
Show SMILES CCCCC1NCCc2cc(Cl)c(O)cc12
Show InChI InChI=1S/C13H18ClNO/c1-2-3-4-12-10-8-13(16)11(14)7-9(10)5-6-15-12/h7-8,12,15-16H,2-6H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
76n/an/an/an/an/an/an/an/a



Universidad de Valencia

Curated by ChEMBL


Assay Description
Displacement of [3H]raclopride from dopamine D2 receptor in Wistar rat striatal membrane by liquid scintillation counting


Bioorg Med Chem 17: 4968-80 (2009)


Article DOI: 10.1016/j.bmc.2009.05.079
BindingDB Entry DOI: 10.7270/Q26D5T2B
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Rattus norvegicus (rat))
BDBM50022051
PNG
(1-Phenyl-6-chloro-7-hydroxy-N-methyl-1,2,3,4-tetra...)
Show SMILES CN1CCc2cc(Cl)c(O)cc2C1c1ccccc1
Show InChI InChI=1S/C16H16ClNO/c1-18-8-7-12-9-14(17)15(19)10-13(12)16(18)11-5-3-2-4-6-11/h2-6,9-10,16,19H,7-8H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
504n/an/an/an/an/an/an/an/a



Universidad de Valencia

Curated by ChEMBL


Assay Description
Displacement of [3H]raclopride from dopamine D2 receptor in Wistar rat striatal membrane by liquid scintillation counting


Bioorg Med Chem 17: 4968-80 (2009)


Article DOI: 10.1016/j.bmc.2009.05.079
BindingDB Entry DOI: 10.7270/Q26D5T2B
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%