Affinity Data by PubMed id=19731939

PubMed code 19731939

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39))	BDBM50300661 (3-borono-5-(2-methoxybenzamido)benzoic acid \| CHEM...) Show SMILES COc1ccccc1C(=O)Nc1cc(cc(c1)C(O)=O)B(O)O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...				J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39))	BDBM50300664 (3-borono-5-(2-phenoxyacetamido)benzoic acid \| CHEM...) Show SMILES OB(O)c1cc(NC(=O)COc2ccccc2)cc(c1)C(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...				J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39))	BDBM50300662 (3-borono-5-(thiophene-2-carboxamido)benzoic acid \|...) Show SMILES OB(O)c1cc(NC(=O)c2cccs2)cc(c1)C(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...				J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39))	BDBM50300660 (3-benzamido-5-boronobenzoic acid \| CHEMBL575719) Show SMILES OB(O)c1cc(NC(=O)c2ccccc2)cc(c1)C(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...				J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39))	BDBM50300663 (3-borono-5-(2-(thiophen-2-yl)acetamido)benzoic aci...) Show SMILES OB(O)c1cc(NC(=O)Cc2cccs2)cc(c1)C(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...				J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39))	BDBM50300659 (3-borono-5-(2-phenylacetamido)benzoic acid \| CHEMB...) Show SMILES OB(O)c1cc(NC(=O)Cc2ccccc2)cc(c1)C(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...				J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
D-alanyl-D-alanine carboxypeptidase (Actinomadura sp. (strain R39))	BDBM50067893 (3-Carboxyphenylboronicacid \| 3-boronobenzoic acid ...) Show SMILES OB(O)c1cccc(c1)C(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of Actinomadura sp. R39 penicillin-binding protein preincubated for 60 mins before addition of substrate mixture of (R)-[2-(benzoylamino)p...				J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 2x (Streptococcus pneumoniae)	BDBM50300665 (5-boronothiophene-2-carboxylic acid \| CHEMBL573906) Show SMILES OB(O)c1ccc(s1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2X preincubated for 4 hrs before addition of substrate mixture of (R)-[2-(benzoyl...				J Med Chem 52: 6097-106 (2009) Article DOI: 10.1021/jm9009718 BindingDB Entry DOI: 10.7270/Q2G73DSS
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%