Affinity Data by PubMed id=20045649

PubMed code 20045649

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50127610 ((1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclo...) Show SMILES NCC[C@@H]1C[C@@H]1c1cnc[nH]1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Binding affinity to histamine H3 receptor				Bioorg Med Chem 18: 1076-82 (2010) Article DOI: 10.1016/j.bmc.2009.12.046 BindingDB Entry DOI: 10.7270/Q21V5F35
Hokkaido University Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50310163 ((1R,2S)-2-[2-(4-Chlorobenzylamino)ethyl]-1-(5(4)-m...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylahistamine from human histamine H3 receptor				Bioorg Med Chem 18: 1076-82 (2010) Article DOI: 10.1016/j.bmc.2009.12.046 BindingDB Entry DOI: 10.7270/Q21V5F35
Hokkaido University Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50310163 ((1R,2S)-2-[2-(4-Chlorobenzylamino)ethyl]-1-(5(4)-m...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor				Bioorg Med Chem 18: 1076-82 (2010) Article DOI: 10.1016/j.bmc.2009.12.046 BindingDB Entry DOI: 10.7270/Q21V5F35
Hokkaido University Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50310164 ((1R,2R)-2-(4-Chlorobenzylamino)methyl-1-(5(4)-meth...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylahistamine from human histamine H3 receptor				Bioorg Med Chem 18: 1076-82 (2010) Article DOI: 10.1016/j.bmc.2009.12.046 BindingDB Entry DOI: 10.7270/Q21V5F35
Hokkaido University Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50310164 ((1R,2R)-2-(4-Chlorobenzylamino)methyl-1-(5(4)-meth...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor				Bioorg Med Chem 18: 1076-82 (2010) Article DOI: 10.1016/j.bmc.2009.12.046 BindingDB Entry DOI: 10.7270/Q21V5F35
Hokkaido University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%