Found 14 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313459
((Z)-4-oxo-4-(p-tolylamino)but-2-enoic acid | CHEMB...)Show InChI InChI=1S/C11H11NO3/c1-8-2-4-9(5-3-8)12-10(13)6-7-11(14)15/h2-7H,1H3,(H,12,13)(H,14,15)/b7-6- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313460
((Z)-4-oxo-4-(phenylamino)but-2-enoic acid | CHEMBL...)Show InChI InChI=1S/C10H9NO3/c12-9(6-7-10(13)14)11-8-4-2-1-3-5-8/h1-7H,(H,11,12)(H,13,14)/b7-6- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.03E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313458
((Z)-4-(4-nitrophenylamino)-4-oxobut-2-enoic acid |...)Show InChI InChI=1S/C10H8N2O5/c13-9(5-6-10(14)15)11-7-1-3-8(4-2-7)12(16)17/h1-6H,(H,11,13)(H,14,15)/b6-5- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.46E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313456
((Z)-methyl 4-(3,4-dichlorophenylamino)-4-oxobut-2-...)Show InChI InChI=1S/C11H9Cl2NO3/c1-17-11(16)5-4-10(15)14-7-2-3-8(12)9(13)6-7/h2-6H,1H3,(H,14,15)/b5-4- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.32E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313457
((Z)-4-(2,6-dimethylphenylamino)-4-oxobut-2-enoic a...)Show InChI InChI=1S/C12H13NO3/c1-8-4-3-5-9(2)12(8)13-10(14)6-7-11(15)16/h3-7H,1-2H3,(H,13,14)(H,15,16)/b7-6- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.34E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313454
((E)-4-(4-chlorophenylamino)-4-oxobut-2-enoic acid ...)Show InChI InChI=1S/C10H8ClNO3/c11-7-1-3-8(4-2-7)12-9(13)5-6-10(14)15/h1-6H,(H,12,13)(H,14,15)/b6-5+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313447
(CHEMBL1086414 | Methyl N-(3,4-dimethylphenyl)fumar...)Show InChI InChI=1S/C13H15NO3/c1-9-4-5-11(8-10(9)2)14-12(15)6-7-13(16)17-3/h4-8H,1-3H3,(H,14,15)/b7-6+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.33E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313450
((E)-4-(4-nitrophenylamino)-4-oxobut-2-enoic acid |...)Show InChI InChI=1S/C10H8N2O5/c13-9(5-6-10(14)15)11-7-1-3-8(4-2-7)12(16)17/h1-6H,(H,11,13)(H,14,15)/b6-5+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.56E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313453
((E)-4-(3,4-dichlorophenylamino)-4-oxobut-2-enoic a...)Show InChI InChI=1S/C10H7Cl2NO3/c11-7-2-1-6(5-8(7)12)13-9(14)3-4-10(15)16/h1-5H,(H,13,14)(H,15,16)/b4-3+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.38E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313451
((E)-4-(3,4-dimethylphenylamino)-4-oxobut-2-enoic a...)Show InChI InChI=1S/C12H13NO3/c1-8-3-4-10(7-9(8)2)13-11(14)5-6-12(15)16/h3-7H,1-2H3,(H,13,14)(H,15,16)/b6-5+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.55E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313448
((E)-methyl 4-(3,4-dichlorophenylamino)-4-oxobut-2-...)Show InChI InChI=1S/C11H9Cl2NO3/c1-17-11(16)5-4-10(15)14-7-2-3-8(12)9(13)6-7/h2-6H,1H3,(H,14,15)/b5-4+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >8.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313452
((E)-4-oxo-4-(p-tolylamino)but-2-enoic acid | 4-oxo...)Show InChI InChI=1S/C11H11NO3/c1-8-2-4-9(5-3-8)12-10(13)6-7-11(14)15/h2-7H,1H3,(H,12,13)(H,14,15)/b7-6+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.35E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313455
((Z)-methyl 4-oxo-4-(p-tolylamino)but-2-enoate | CH...)Show InChI InChI=1S/C12H13NO3/c1-9-3-5-10(6-4-9)13-11(14)7-8-12(15)16-2/h3-8H,1-2H3,(H,13,14)/b8-7- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50313449
((E)-methyl 4-(4-chlorophenylamino)-4-oxobut-2-enoa...)Show InChI InChI=1S/C11H10ClNO3/c1-16-11(15)7-6-10(14)13-9-4-2-8(12)3-5-9/h2-7H,1H3,(H,13,14)/b7-6+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
Acadia University
Curated by ChEMBL
| Assay Description Inhibition of human NMT expressed in Escherichia coli DH5alpha cells |
Bioorg Med Chem Lett 20: 1510-5 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.098 BindingDB Entry DOI: 10.7270/Q28P60NS |
More data for this Ligand-Target Pair | |