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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM36486 (9-Cyclopentyl-2-(2-ethoxy-4-(4-hydroxypiperidin-1-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 145 | n/a | n/a | n/a | n/a | 7.5 | 0 |
Dana-Farber Cancer Institute | Assay Description ATP-site competition binding assay using Mps1 Kinase inhibitors in LanthaScreen Eu time-resolved FRET (TR-FRET) technology from Invitrogen. | Nat Chem Biol 6: 359-68 (2010) Article DOI: 10.1038/nchembio.345 BindingDB Entry DOI: 10.7270/Q27D2SGG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM36485 (1-(4-(4-(2-(Isopropylsulfonyl)phenylamino)-1H-pyrr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem | MMDB PDB Article PubMed | n/a | n/a | 367 | n/a | n/a | n/a | n/a | 7.5 | 0 |
Dana-Farber Cancer Institute | Assay Description ATP-site competition binding assay using Mps1 Kinase inhibitors in LanthaScreen Eu time-resolved FRET (TR-FRET) technology from Invitrogen. | Nat Chem Biol 6: 359-68 (2010) Article DOI: 10.1038/nchembio.345 BindingDB Entry DOI: 10.7270/Q27D2SGG | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
