Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human)) | BDBM50316814 (CHEMBL1097104 | cryptosphaerolide) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-San Diego Curated by ChEMBL | Assay Description Inhibition of Mcl1 protein by Mcl1/Bak fluorescence resonance assay | J Nat Prod 73: 998-1001 (2010) Article DOI: 10.1021/np1000889 BindingDB Entry DOI: 10.7270/Q2RR1ZCX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human)) | BDBM50316815 ((1R,3S,4R,8S,10R,11S,14R)-4-methoxy-10,11-dimethyl...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-San Diego Curated by ChEMBL | Assay Description Inhibition of Mcl1 protein by Mcl1/Bak fluorescence resonance assay | J Nat Prod 73: 998-1001 (2010) Article DOI: 10.1021/np1000889 BindingDB Entry DOI: 10.7270/Q2RR1ZCX | |||||||||||
More data for this Ligand-Target Pair |