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PubMed code 20627594

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prolyl endopeptidase


(Homo sapiens (Human))
BDBM50038879
PNG
((S)-2-(2-Formyl-pyrrolidine-1-carbonyl)-pyrrolidin...)
Show SMILES O=C[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 |r|
Show InChI InChI=1S/C18H22N2O4/c21-12-15-8-4-10-19(15)17(22)16-9-5-11-20(16)18(23)24-13-14-6-2-1-3-7-14/h1-3,6-7,12,15-16H,4-5,8-11,13H2/t15-,16-/m0/s1
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MCE
PC cid
PC sid
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PDB
Article
PubMed
4.30n/an/an/an/an/an/an/an/a



The University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of prolyl oligopeptidase


Bioorg Med Chem 18: 4775-82 (2011)


Article DOI: 10.1016/j.bmc.2010.05.012
BindingDB Entry DOI: 10.7270/Q2000319
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Prolyl endopeptidase


(Homo sapiens (Human))
BDBM50321860
PNG
((S)-benzyl2-((S)-2-formylpiperidine-1-carbonyl)pyr...)
Show SMILES O=C[C@@H]1CCCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 |r|
Show InChI InChI=1S/C19H24N2O4/c22-13-16-9-4-5-11-20(16)18(23)17-10-6-12-21(17)19(24)25-14-15-7-2-1-3-8-15/h1-3,7-8,13,16-17H,4-6,9-12,14H2/t16-,17-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 26n/an/an/an/an/an/a



The University of Warwick

Curated by ChEMBL


Assay Description
Inhibition of prolyl oligopeptidase


Bioorg Med Chem 18: 4775-82 (2011)


Article DOI: 10.1016/j.bmc.2010.05.012
BindingDB Entry DOI: 10.7270/Q2000319
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%