Found 47 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17478
(2-benzenesulfonamido-5,6,7,8-tetrahydronaphthalene...)Show InChI InChI=1S/C17H17NO4S/c19-17(20)16-14-9-5-4-6-12(14)10-11-15(16)18-23(21,22)13-7-2-1-3-8-13/h1-3,7-8,10-11,18H,4-6,9H2,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17505
(2-[(2-{[3-(1H-imidazol-1-yl)propyl]amino}benzene)s...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCCn2ccnc2)ccc2CCCCc12 Show InChI InChI=1S/C23H26N4O4S/c28-23(29)22-18-7-2-1-6-17(18)10-11-20(22)26-32(30,31)21-9-4-3-8-19(21)25-12-5-14-27-15-13-24-16-27/h3-4,8-11,13,15-16,25-26H,1-2,5-7,12,14H2,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17488
(2-[(2-{[3-(ethylamino)propyl]amino}benzene)sulfona...)Show SMILES CCNCCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C22H29N3O4S/c1-2-23-14-7-15-24-18-10-5-6-11-20(18)30(28,29)25-19-13-12-16-8-3-4-9-17(16)21(19)22(26)27/h5-6,10-13,23-25H,2-4,7-9,14-15H2,1H3,(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12.0 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17519
(2-[(2-{[4-(dimethylamino)butyl]amino}benzene)sulfo...)Show SMILES CN(C)CCCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C23H31N3O4S/c1-26(2)16-8-7-15-24-19-11-5-6-12-21(19)31(29,30)25-20-14-13-17-9-3-4-10-18(17)22(20)23(27)28/h5-6,11-14,24-25H,3-4,7-10,15-16H2,1-2H3,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12.0 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17492
(2-({2-[(3-aminopropyl)amino]benzene}sulfonamido)-5...)Show SMILES NCCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C20H25N3O4S/c21-12-5-13-22-16-8-3-4-9-18(16)28(26,27)23-17-11-10-14-6-1-2-7-15(14)19(17)20(24)25/h3-4,8-11,22-23H,1-2,5-7,12-13,21H2,(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17521
(2-[(2-aminobenzene)sulfonamido]-5,6,7,8-tetrahydro...)Show InChI InChI=1S/C17H18N2O4S/c18-13-7-3-4-8-15(13)24(22,23)19-14-10-9-11-5-1-2-6-12(11)16(14)17(20)21/h3-4,7-10,19H,1-2,5-6,18H2,(H,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17483
(2-[(2-{[3-(dimethylamino)propyl]amino}benzene)sulf...)Show SMILES CN(C)CCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C22H29N3O4S/c1-25(2)15-7-14-23-18-10-5-6-11-20(18)30(28,29)24-19-13-12-16-8-3-4-9-17(16)21(19)22(26)27/h5-6,10-13,23-24H,3-4,7-9,14-15H2,1-2H3,(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17527
(2-[(2-{[(1-methylpiperidin-4-yl)methyl]amino}benze...)Show SMILES CN1CCC(CNc2ccccc2S(=O)(=O)Nc2ccc3CCCCc3c2C(O)=O)CC1 Show InChI InChI=1S/C24H31N3O4S/c1-27-14-12-17(13-15-27)16-25-20-8-4-5-9-22(20)32(30,31)26-21-11-10-18-6-2-3-7-19(18)23(21)24(28)29/h4-5,8-11,17,25-26H,2-3,6-7,12-16H2,1H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17489
(2-{[2-({3-[(2-hydroxyethyl)amino]propyl}amino)benz...)Show SMILES OCCNCCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C22H29N3O5S/c26-15-14-23-12-5-13-24-18-8-3-4-9-20(18)31(29,30)25-19-11-10-16-6-1-2-7-17(16)21(19)22(27)28/h3-4,8-11,23-26H,1-2,5-7,12-15H2,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17512
(2-[(3-chloro-2-{[3-(diethylamino)propyl]amino}benz...)Show SMILES CCN(CC)CCCNc1c(Cl)cccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C24H32ClN3O4S/c1-3-28(4-2)16-8-15-26-23-19(25)11-7-12-21(23)33(31,32)27-20-14-13-17-9-5-6-10-18(17)22(20)24(29)30/h7,11-14,26-27H,3-6,8-10,15-16H2,1-2H3,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17508
(2-[(2-{[2-(pyridin-4-yl)ethyl]amino}benzene)sulfon...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCc2ccncc2)ccc2CCCCc12 Show InChI InChI=1S/C24H25N3O4S/c28-24(29)23-19-6-2-1-5-18(19)9-10-21(23)27-32(30,31)22-8-4-3-7-20(22)26-16-13-17-11-14-25-15-12-17/h3-4,7-12,14-15,26-27H,1-2,5-6,13,16H2,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17496
(2-[(2-{[3-(pyrrolidin-1-yl)propyl]amino}benzene)su...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCCN2CCCC2)ccc2CCCCc12 Show InChI InChI=1S/C24H31N3O4S/c28-24(29)23-19-9-2-1-8-18(19)12-13-21(23)26-32(30,31)22-11-4-3-10-20(22)25-14-7-17-27-15-5-6-16-27/h3-4,10-13,25-26H,1-2,5-9,14-17H2,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17.0 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17502
(2-({2-[(piperidin-4-ylmethyl)amino]benzene}sulfona...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCC2CCNCC2)ccc2CCCCc12 Show InChI InChI=1S/C23H29N3O4S/c27-23(28)22-18-6-2-1-5-17(18)9-10-20(22)26-31(29,30)21-8-4-3-7-19(21)25-15-16-11-13-24-14-12-16/h3-4,7-10,16,24-26H,1-2,5-6,11-15H2,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17.0 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17497
(2-[(2-{[2-(1-methylpyrrolidin-2-yl)ethyl]amino}ben...)Show SMILES CN1CCCC1CCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C24H31N3O4S/c1-27-16-6-8-18(27)14-15-25-20-10-4-5-11-22(20)32(30,31)26-21-13-12-17-7-2-3-9-19(17)23(21)24(28)29/h4-5,10-13,18,25-26H,2-3,6-9,14-16H2,1H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17.0 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17486
(2-{[2-({2-[(dimethylamino)methyl]-2-methylpropyl}a...)Show SMILES CN(C)CC(C)(C)CNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C24H33N3O4S/c1-24(2,16-27(3)4)15-25-19-11-7-8-12-21(19)32(30,31)26-20-14-13-17-9-5-6-10-18(17)22(20)23(28)29/h7-8,11-14,25-26H,5-6,9-10,15-16H2,1-4H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17510
(2-[(2-{[3-(diethylamino)propyl]amino}-6-fluorobenz...)Show SMILES CCN(CC)CCCNc1cccc(F)c1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C24H32FN3O4S/c1-3-28(4-2)16-8-15-26-21-12-7-11-19(25)23(21)33(31,32)27-20-14-13-17-9-5-6-10-18(17)22(20)24(29)30/h7,11-14,26-27H,3-6,8-10,15-16H2,1-2H3,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17494
(2-[(2-{[3-(piperidin-1-yl)propyl]amino}benzene)sul...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCCN2CCCCC2)ccc2CCCCc12 Show InChI InChI=1S/C25H33N3O4S/c29-25(30)24-20-10-3-2-9-19(20)13-14-22(24)27-33(31,32)23-12-5-4-11-21(23)26-15-8-18-28-16-6-1-7-17-28/h4-5,11-14,26-27H,1-3,6-10,15-18H2,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17495
(2-[(2-{[3-(morpholin-4-yl)propyl]amino}benzene)sul...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCCN2CCOCC2)ccc2CCCCc12 Show InChI InChI=1S/C24H31N3O5S/c28-24(29)23-19-7-2-1-6-18(19)10-11-21(23)26-33(30,31)22-9-4-3-8-20(22)25-12-5-13-27-14-16-32-17-15-27/h3-4,8-11,25-26H,1-2,5-7,12-17H2,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 21.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17503
(2-[(2-{[2-(pyrrolidin-2-yl)ethyl]amino}benzene)sul...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCC2CCCN2)ccc2CCCCc12 Show InChI InChI=1S/C23H29N3O4S/c27-23(28)22-18-8-2-1-6-16(18)11-12-20(22)26-31(29,30)21-10-4-3-9-19(21)25-15-13-17-7-5-14-24-17/h3-4,9-12,17,24-26H,1-2,5-8,13-15H2,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 21.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17493
(2-[(2-{[3-(4-methylpiperazin-1-yl)propyl]amino}ben...)Show SMILES CN1CCN(CCCNc2ccccc2S(=O)(=O)Nc2ccc3CCCCc3c2C(O)=O)CC1 Show InChI InChI=1S/C25H34N4O4S/c1-28-15-17-29(18-16-28)14-6-13-26-21-9-4-5-10-23(21)34(32,33)27-22-12-11-19-7-2-3-8-20(19)24(22)25(30)31/h4-5,9-12,26-27H,2-3,6-8,13-18H2,1H3,(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17487
(2-{[2-({3-[bis(2-hydroxyethyl)amino]propyl}amino)b...)Show SMILES OCCN(CCO)CCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C24H33N3O6S/c28-16-14-27(15-17-29)13-5-12-25-20-8-3-4-9-22(20)34(32,33)26-21-11-10-18-6-1-2-7-19(18)23(21)24(30)31/h3-4,8-11,25-26,28-29H,1-2,5-7,12-17H2,(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17481
(2-{[2-({2-[bis(propan-2-yl)amino]ethyl}amino)benze...)Show SMILES CC(C)N(CCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O)C(C)C Show InChI InChI=1S/C25H35N3O4S/c1-17(2)28(18(3)4)16-15-26-21-11-7-8-12-23(21)33(31,32)27-22-14-13-19-9-5-6-10-20(19)24(22)25(29)30/h7-8,11-14,17-18,26-27H,5-6,9-10,15-16H2,1-4H3,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17480
(2-[(2-{[2-(diethylamino)ethyl]amino}benzene)sulfon...)Show SMILES CCN(CC)CCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C23H31N3O4S/c1-3-26(4-2)16-15-24-19-11-7-8-12-21(19)31(29,30)25-20-14-13-17-9-5-6-10-18(17)22(20)23(27)28/h7-8,11-14,24-25H,3-6,9-10,15-16H2,1-2H3,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17501
(2-({2-[(pyrrolidin-3-ylmethyl)amino]benzene}sulfon...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCC2CCNC2)ccc2CCCCc12 Show InChI InChI=1S/C22H27N3O4S/c26-22(27)21-17-6-2-1-5-16(17)9-10-19(21)25-30(28,29)20-8-4-3-7-18(20)24-14-15-11-12-23-13-15/h3-4,7-10,15,23-25H,1-2,5-6,11-14H2,(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 33.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17500
(2-({2-[(piperidin-3-ylmethyl)amino]benzene}sulfona...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCC2CCCNC2)ccc2CCCCc12 Show InChI InChI=1S/C23H29N3O4S/c27-23(28)22-18-8-2-1-7-17(18)11-12-20(22)26-31(29,30)21-10-4-3-9-19(21)25-15-16-6-5-13-24-14-16/h3-4,9-12,16,24-26H,1-2,5-8,13-15H2,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 34.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17506
(2-({2-[(pyridin-4-ylmethyl)amino]benzene}sulfonami...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCc2ccncc2)ccc2CCCCc12 Show InChI InChI=1S/C23H23N3O4S/c27-23(28)22-18-6-2-1-5-17(18)9-10-20(22)26-31(29,30)21-8-4-3-7-19(21)25-15-16-11-13-24-14-12-16/h3-4,7-14,25-26H,1-2,5-6,15H2,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 34.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17509
(2-[(2-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}benze...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCCN2CCCC2=O)ccc2CCCCc12 Show InChI InChI=1S/C24H29N3O5S/c28-22-11-5-15-27(22)16-6-14-25-19-9-3-4-10-21(19)33(31,32)26-20-13-12-17-7-1-2-8-18(17)23(20)24(29)30/h3-4,9-10,12-13,25-26H,1-2,5-8,11,14-16H2,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17522
(2-{[2-({[1-(propan-2-yl)piperidin-4-yl]methyl}amin...)Show SMILES CC(C)N1CCC(CNc2ccccc2S(=O)(=O)Nc2ccc3CCCCc3c2C(O)=O)CC1 Show InChI InChI=1S/C26H35N3O4S/c1-18(2)29-15-13-19(14-16-29)17-27-22-9-5-6-10-24(22)34(32,33)28-23-12-11-20-7-3-4-8-21(20)25(23)26(30)31/h5-6,9-12,18-19,27-28H,3-4,7-8,13-17H2,1-2H3,(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 45.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17479
(2-[(2-{[2-(dimethylamino)ethyl]amino}benzene)sulfo...)Show SMILES CN(C)CCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C21H27N3O4S/c1-24(2)14-13-22-17-9-5-6-10-19(17)29(27,28)23-18-12-11-15-7-3-4-8-16(15)20(18)21(25)26/h5-6,9-12,22-23H,3-4,7-8,13-14H2,1-2H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 47.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17507
(2-[(2-{[2-(pyridin-2-yl)ethyl]amino}benzene)sulfon...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCc2ccccn2)ccc2CCCCc12 Show InChI InChI=1S/C24H25N3O4S/c28-24(29)23-19-9-2-1-7-17(19)12-13-21(23)27-32(30,31)22-11-4-3-10-20(22)26-16-14-18-8-5-6-15-25-18/h3-6,8,10-13,15,26-27H,1-2,7,9,14,16H2,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 52.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM50416841
(CHEMBL1254633)Show SMILES CCCN(CCC)CCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C26H37N3O4S/c1-3-17-29(18-4-2)19-9-16-27-22-12-7-8-13-24(22)34(32,33)28-23-15-14-20-10-5-6-11-21(20)25(23)26(30)31/h7-8,12-15,27-28H,3-6,9-11,16-19H2,1-2H3,(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 52.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17528
(2-{[2-({[1-(1-methylpiperidin-4-yl)piperidin-4-yl]...)Show SMILES CN1CCC(CC1)N1CCC(CNc2ccccc2S(=O)(=O)Nc2ccc3CCCCc3c2C(O)=O)CC1 Show InChI InChI=1S/C29H40N4O4S/c1-32-16-14-23(15-17-32)33-18-12-21(13-19-33)20-30-25-8-4-5-9-27(25)38(36,37)31-26-11-10-22-6-2-3-7-24(22)28(26)29(34)35/h4-5,8-11,21,23,30-31H,2-3,6-7,12-20H2,1H3,(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 55.0 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17513
(2-[(5-chloro-2-{[3-(diethylamino)propyl]amino}benz...)Show SMILES CCN(CC)CCCNc1ccc(Cl)cc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C24H32ClN3O4S/c1-3-28(4-2)15-7-14-26-20-13-11-18(25)16-22(20)33(31,32)27-21-12-10-17-8-5-6-9-19(17)23(21)24(29)30/h10-13,16,26-27H,3-9,14-15H2,1-2H3,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 56.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17504
(2-{[2-({3-[4-(piperidin-1-yl)piperidin-1-yl]propyl...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCCN2CCC(CC2)N2CCCCC2)ccc2CCCCc12 Show InChI InChI=1S/C30H42N4O4S/c35-30(36)29-25-10-3-2-9-23(25)13-14-27(29)32-39(37,38)28-12-5-4-11-26(28)31-17-8-18-33-21-15-24(16-22-33)34-19-6-1-7-20-34/h4-5,11-14,24,31-32H,1-3,6-10,15-22H2,(H,35,36) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 57.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17526
(2-{[2-({2-[1-(propan-2-yl)pyrrolidin-2-yl]ethyl}am...)Show SMILES CC(C)N1CCCC1CCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C26H35N3O4S/c1-18(2)29-17-7-9-20(29)15-16-27-22-11-5-6-12-24(22)34(32,33)28-23-14-13-19-8-3-4-10-21(19)25(23)26(30)31/h5-6,11-14,18,20,27-28H,3-4,7-10,15-17H2,1-2H3,(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 61.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17515
(2-[(2-{[3-(diethylamino)propyl]amino}-5-methylbenz...)Show SMILES CCN(CC)CCCNc1ccc(C)cc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C25H35N3O4S/c1-4-28(5-2)16-8-15-26-21-13-11-18(3)17-23(21)33(31,32)27-22-14-12-19-9-6-7-10-20(19)24(22)25(29)30/h11-14,17,26-27H,4-10,15-16H2,1-3H3,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 66.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17482
(2-[(2-{[2-(pyrrolidin-1-yl)ethyl]amino}benzene)sul...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCN2CCCC2)ccc2CCCCc12 Show InChI InChI=1S/C23H29N3O4S/c27-23(28)22-18-8-2-1-7-17(18)11-12-20(22)25-31(29,30)21-10-4-3-9-19(21)24-13-16-26-14-5-6-15-26/h3-4,9-12,24-25H,1-2,5-8,13-16H2,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 69.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17525
(2-[(2-{[2-(1-cyclohexylpyrrolidin-2-yl)ethyl]amino...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCC2CCCN2C2CCCCC2)ccc2CCCCc12 Show InChI InChI=1S/C29H39N3O4S/c33-29(34)28-24-13-5-4-9-21(24)16-17-26(28)31-37(35,36)27-15-7-6-14-25(27)30-19-18-23-12-8-20-32(23)22-10-2-1-3-11-22/h6-7,14-17,22-23,30-31H,1-5,8-13,18-20H2,(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 69.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17524
(2-{[2-({2-[1-(1-methylpiperidin-4-yl)pyrrolidin-2-...)Show SMILES CN1CCC(CC1)N1CCCC1CCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C29H40N4O4S/c1-32-19-15-23(16-20-32)33-18-6-8-22(33)14-17-30-25-10-4-5-11-27(25)38(36,37)31-26-13-12-21-7-2-3-9-24(21)28(26)29(34)35/h4-5,10-13,22-23,30-31H,2-3,6-9,14-20H2,1H3,(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 70.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17490
(2-({2-[(3-{[(tert-butoxy)carbonyl]amino}propyl)ami...)Show SMILES CC(C)(C)OC(=O)NCCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C25H33N3O6S/c1-25(2,3)34-24(31)27-16-8-15-26-19-11-6-7-12-21(19)35(32,33)28-20-14-13-17-9-4-5-10-18(17)22(20)23(29)30/h6-7,11-14,26,28H,4-5,8-10,15-16H2,1-3H3,(H,27,31)(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 77.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM50416843
(CHEMBL1253792)Show SMILES CC1(C)CC(CC(C)(C)N1)Nc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C26H35N3O4S/c1-25(2)15-18(16-26(3,4)29-25)27-20-11-7-8-12-22(20)34(32,33)28-21-14-13-17-9-5-6-10-19(17)23(21)24(30)31/h7-8,11-14,18,27-29H,5-6,9-10,15-16H2,1-4H3,(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 91.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17491
(2-({2-[(3-{[(tert-butoxy)carbonyl](methyl)amino}pr...)Show SMILES CN(CCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O)C(=O)OC(C)(C)C Show InChI InChI=1S/C26H35N3O6S/c1-26(2,3)35-25(32)29(4)17-9-16-27-20-12-7-8-13-22(20)36(33,34)28-21-15-14-18-10-5-6-11-19(18)23(21)24(30)31/h7-8,12-15,27-28H,5-6,9-11,16-17H2,1-4H3,(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17516
(2-[(4-chloro-2-{[3-(diethylamino)propyl]amino}benz...)Show SMILES CCN(CC)CCCNc1cc(Cl)ccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C24H32ClN3O4S/c1-3-28(4-2)15-7-14-26-21-16-18(25)11-13-22(21)33(31,32)27-20-12-10-17-8-5-6-9-19(17)23(20)24(29)30/h10-13,16,26-27H,3-9,14-15H2,1-2H3,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM50416842
(CHEMBL1254559)Show SMILES CCN(CC)CCC(C)Nc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C25H35N3O4S/c1-4-28(5-2)17-16-18(3)26-21-12-8-9-13-23(21)33(31,32)27-22-15-14-19-10-6-7-11-20(19)24(22)25(29)30/h8-9,12-15,18,26-27H,4-7,10-11,16-17H2,1-3H3,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 129 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17523
(2-{[2-({2-[1-(cyclohexylmethyl)pyrrolidin-2-yl]eth...)Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCC2CCCN2CC2CCCCC2)ccc2CCCCc12 Show InChI InChI=1S/C30H41N3O4S/c34-30(35)29-25-13-5-4-11-23(25)16-17-27(29)32-38(36,37)28-15-7-6-14-26(28)31-19-18-24-12-8-20-33(24)21-22-9-2-1-3-10-22/h6-7,14-17,22,24,31-32H,1-5,8-13,18-21H2,(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 151 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17517
(2-[(2-{[3-(diethylamino)propyl]amino}-4-methylbenz...)Show SMILES CCN(CC)CCCNc1cc(C)ccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C25H35N3O4S/c1-4-28(5-2)16-8-15-26-22-17-18(3)11-14-23(22)33(31,32)27-21-13-12-19-9-6-7-10-20(19)24(21)25(29)30/h11-14,17,26-27H,4-10,15-16H2,1-3H3,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 151 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM17484
(2-[(2-{[3-(diethylamino)propyl]amino}benzene)sulfo...)Show SMILES CCN(CC)CCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C24H33N3O4S/c1-3-27(4-2)17-9-16-25-20-12-7-8-13-22(20)32(30,31)26-21-15-14-18-10-5-6-11-19(18)23(21)24(28)29/h7-8,12-15,25-26H,3-6,9-11,16-17H2,1-2H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 182 | n/a | n/a | n/a | n/a | n/a | n/a |
Kermanshah University of Medical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of methionine aminopeptidase 2 |
Eur J Med Chem 45: 4499-508 (2010)
Article DOI: 10.1016/j.ejmech.2010.07.010
BindingDB Entry DOI: 10.7270/Q2KK9D1K |
More data for this
Ligand-Target Pair | |
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