Affinity Data by PubMed id=20943396

PubMed code 20943396

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50330764 (2-(4-Trifluoromethylphenyl)-4(5)-phenylimidazole \|...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording technique				Bioorg Med Chem 18: 7957-65 (2010) Article DOI: 10.1016/j.bmc.2010.09.029 BindingDB Entry DOI: 10.7270/Q26973T7
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50330765 (2-Phenyl-4(5)-(3-chlorophenyl)imidazole \| 4-(3-chl...) Show SMILES Clc1cccc(c1)-c1c[nH]c(n1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording technique				Bioorg Med Chem 18: 7957-65 (2010) Article DOI: 10.1016/j.bmc.2010.09.029 BindingDB Entry DOI: 10.7270/Q26973T7
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50330763 (2-(4-Methoxyphenyl)-4(5)-phenylimidazole \| 2-(4-me...) Show SMILES COc1ccc(cc1)-c1nc(c[nH]1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording technique				Bioorg Med Chem 18: 7957-65 (2010) Article DOI: 10.1016/j.bmc.2010.09.029 BindingDB Entry DOI: 10.7270/Q26973T7
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50133778 (2,4(5)-Diphenylimidazole \| 2,4-diphenyl-1H-imidazo...) Show SMILES c1[nH]c(nc1-c1ccccc1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording technique				Bioorg Med Chem 18: 7957-65 (2010) Article DOI: 10.1016/j.bmc.2010.09.029 BindingDB Entry DOI: 10.7270/Q26973T7
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50003655 (Phenytoin) Show SMILES O=C1NC(=O)C(N1)(c1ccccc1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording technique				Bioorg Med Chem 18: 7957-65 (2010) Article DOI: 10.1016/j.bmc.2010.09.029 BindingDB Entry DOI: 10.7270/Q26973T7
Università degli Studi di Parma Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%