Found 40 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336012
(6-chloro-8-(4-chlorophenyl)-2-(trifluoromethyl)-2H...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(-c3ccc(Cl)cc3)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C17H9Cl2F3O3/c18-10-3-1-8(2-4-10)12-7-11(19)5-9-6-13(16(23)24)15(17(20,21)22)25-14(9)12/h1-7,15H,(H,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
PDB
Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336018
(6-chloro-8-(3-fluoro-4-methylphenyl)-2-(trifluorom...)Show SMILES Cc1ccc(cc1F)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:15| Show InChI InChI=1S/C18H11ClF4O3/c1-8-2-3-9(6-14(8)20)12-7-11(19)4-10-5-13(17(24)25)16(18(21,22)23)26-15(10)12/h2-7,16H,1H3,(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336014
(6-chloro-8-(4-ethylphenyl)-2-(trifluoromethyl)-2H-...)Show SMILES CCc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:15| Show InChI InChI=1S/C19H14ClF3O3/c1-2-10-3-5-11(6-4-10)14-9-13(20)7-12-8-15(18(24)25)17(19(21,22)23)26-16(12)14/h3-9,17H,2H2,1H3,(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336013
(6-chloro-8-p-tolyl-2-(trifluoromethyl)-2H-chromene...)Show SMILES Cc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:14| Show InChI InChI=1S/C18H12ClF3O3/c1-9-2-4-10(5-3-9)13-8-12(19)6-11-7-14(17(23)24)16(18(20,21)22)25-15(11)13/h2-8,16H,1H3,(H,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 103 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50331883
(6-chloro-8-phenyl-2-(trifluoromethyl)-2H-chromene-...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(-c3ccccc3)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C17H10ClF3O3/c18-11-6-10-7-13(16(22)23)15(17(19,20)21)24-14(10)12(8-11)9-4-2-1-3-5-9/h1-8,15H,(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 188 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336012
(6-chloro-8-(4-chlorophenyl)-2-(trifluoromethyl)-2H...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(-c3ccc(Cl)cc3)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C17H9Cl2F3O3/c18-10-3-1-8(2-4-10)12-7-11(19)5-9-6-13(16(23)24)15(17(20,21)22)25-14(9)12/h1-7,15H,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 242 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336016
(6-chloro-8-(4-(ethylthio)phenyl)-2-(trifluoromethy...)Show SMILES CCSc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:16| Show InChI InChI=1S/C19H14ClF3O3S/c1-2-27-13-5-3-10(4-6-13)14-9-12(20)7-11-8-15(18(24)25)17(19(21,22)23)26-16(11)14/h3-9,17H,2H2,1H3,(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 242 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50331875
(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(Cl)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C11H5Cl2F3O3/c12-5-1-4-2-6(10(17)18)9(11(14,15)16)19-8(4)7(13)3-5/h1-3,9H,(H,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50331875
(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(Cl)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C11H5Cl2F3O3/c12-5-1-4-2-6(10(17)18)9(11(14,15)16)19-8(4)7(13)3-5/h1-3,9H,(H,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336019
(6-chloro-8-(4-methoxy-3-methylphenyl)-2-(trifluoro...)Show SMILES COc1ccc(cc1C)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:16| Show InChI InChI=1S/C19H14ClF3O4/c1-9-5-10(3-4-15(9)26-2)13-8-12(20)6-11-7-14(18(24)25)17(19(21,22)23)27-16(11)13/h3-8,17H,1-2H3,(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 339 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336015
(6-chloro-8-(4-ethoxyphenyl)-2-(trifluoromethyl)-2H...)Show SMILES CCOc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:16| Show InChI InChI=1S/C19H14ClF3O4/c1-2-26-13-5-3-10(4-6-13)14-9-12(20)7-11-8-15(18(24)25)17(19(21,22)23)27-16(11)14/h3-9,17H,2H2,1H3,(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 355 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336011
(6-chloro-8-(4-fluorophenyl)-2-(trifluoromethyl)-2H...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(-c3ccc(F)cc3)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C17H9ClF4O3/c18-10-5-9-6-13(16(23)24)15(17(20,21)22)25-14(9)12(7-10)8-1-3-11(19)4-2-8/h1-7,15H,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50331885
(6-chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)...)Show SMILES NS(=O)(=O)c1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:17| Show InChI InChI=1S/C17H11ClF3NO5S/c18-10-5-9-6-13(16(23)24)15(17(19,20)21)27-14(9)12(7-10)8-1-3-11(4-2-8)28(22,25)26/h1-7,15H,(H,23,24)(H2,22,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 758 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336006
(8-(4-aminophenyl)-6-chloro-2-(trifluoromethyl)-2H-...)Show SMILES Nc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:14| Show InChI InChI=1S/C17H11ClF3NO3/c18-10-5-9-6-13(16(23)24)15(17(19,20)21)25-14(9)12(7-10)8-1-3-11(22)4-2-8/h1-7,15H,22H2,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50331883
(6-chloro-8-phenyl-2-(trifluoromethyl)-2H-chromene-...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(-c3ccccc3)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C17H10ClF3O3/c18-11-6-10-7-13(16(22)23)15(17(19,20)21)24-14(10)12(8-11)9-4-2-1-3-5-9/h1-8,15H,(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336006
(8-(4-aminophenyl)-6-chloro-2-(trifluoromethyl)-2H-...)Show SMILES Nc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:14| Show InChI InChI=1S/C17H11ClF3NO3/c18-10-5-9-6-13(16(23)24)15(17(19,20)21)25-14(9)12(7-10)8-1-3-11(22)4-2-8/h1-7,15H,22H2,(H,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336008
(6-chloro-8-(4-(hydroxymethyl)phenyl)-2-(trifluorom...)Show SMILES OCc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:15| Show InChI InChI=1S/C18H12ClF3O4/c19-12-5-11-6-14(17(24)25)16(18(20,21)22)26-15(11)13(7-12)10-3-1-9(8-23)2-4-10/h1-7,16,23H,8H2,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336009
(6-chloro-8-(4-hydroxyphenyl)-2-(trifluoromethyl)-2...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(-c3ccc(O)cc3)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C17H10ClF3O4/c18-10-5-9-6-13(16(23)24)15(17(19,20)21)25-14(9)12(7-10)8-1-3-11(22)4-2-8/h1-7,15,22H,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336009
(6-chloro-8-(4-hydroxyphenyl)-2-(trifluoromethyl)-2...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(-c3ccc(O)cc3)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C17H10ClF3O4/c18-10-5-9-6-13(16(23)24)15(17(19,20)21)25-14(9)12(7-10)8-1-3-11(22)4-2-8/h1-7,15,22H,(H,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336005
(6-chloro-8-(4-(methylsulfonyl)phenyl)-2-(trifluoro...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:17| Show InChI InChI=1S/C18H12ClF3O5S/c1-28(25,26)12-4-2-9(3-5-12)13-8-11(19)6-10-7-14(17(23)24)16(18(20,21)22)27-15(10)13/h2-8,16H,1H3,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336013
(6-chloro-8-p-tolyl-2-(trifluoromethyl)-2H-chromene...)Show SMILES Cc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:14| Show InChI InChI=1S/C18H12ClF3O3/c1-9-2-4-10(5-3-9)13-8-12(19)6-11-7-14(17(23)24)16(18(20,21)22)25-15(11)13/h2-8,16H,1H3,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336008
(6-chloro-8-(4-(hydroxymethyl)phenyl)-2-(trifluorom...)Show SMILES OCc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:15| Show InChI InChI=1S/C18H12ClF3O4/c19-12-5-11-6-14(17(24)25)16(18(20,21)22)26-15(11)13(7-12)10-3-1-9(8-23)2-4-10/h1-7,16,23H,8H2,(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336017
(6-chloro-8-(4-isobutylphenyl)-2-(trifluoromethyl)-...)Show SMILES CC(C)Cc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:17| Show InChI InChI=1S/C21H18ClF3O3/c1-11(2)7-12-3-5-13(6-4-12)16-10-15(22)8-14-9-17(20(26)27)19(21(23,24)25)28-18(14)16/h3-6,8-11,19H,7H2,1-2H3,(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336014
(6-chloro-8-(4-ethylphenyl)-2-(trifluoromethyl)-2H-...)Show SMILES CCc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:15| Show InChI InChI=1S/C19H14ClF3O3/c1-2-10-3-5-11(6-4-10)14-9-13(20)7-12-8-15(18(24)25)17(19(21,22)23)26-16(12)14/h3-9,17H,2H2,1H3,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336005
(6-chloro-8-(4-(methylsulfonyl)phenyl)-2-(trifluoro...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:17| Show InChI InChI=1S/C18H12ClF3O5S/c1-28(25,26)12-4-2-9(3-5-12)13-8-11(19)6-10-7-14(17(23)24)16(18(20,21)22)27-15(10)13/h2-8,16H,1H3,(H,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336018
(6-chloro-8-(3-fluoro-4-methylphenyl)-2-(trifluorom...)Show SMILES Cc1ccc(cc1F)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:15| Show InChI InChI=1S/C18H11ClF4O3/c1-8-2-3-9(6-14(8)20)12-7-11(19)4-10-5-13(17(24)25)16(18(21,22)23)26-15(10)12/h2-7,16H,1H3,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336017
(6-chloro-8-(4-isobutylphenyl)-2-(trifluoromethyl)-...)Show SMILES CC(C)Cc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:17| Show InChI InChI=1S/C21H18ClF3O3/c1-11(2)7-12-3-5-13(6-4-12)16-10-15(22)8-14-9-17(20(26)27)19(21(23,24)25)28-18(14)16/h3-6,8-11,19H,7H2,1-2H3,(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50331875
(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(Cl)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C11H5Cl2F3O3/c12-5-1-4-2-6(10(17)18)9(11(14,15)16)19-8(4)7(13)3-5/h1-3,9H,(H,17,18) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336015
(6-chloro-8-(4-ethoxyphenyl)-2-(trifluoromethyl)-2H...)Show SMILES CCOc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:16| Show InChI InChI=1S/C19H14ClF3O4/c1-2-26-13-5-3-10(4-6-13)14-9-12(20)7-11-8-15(18(24)25)17(19(21,22)23)27-16(11)14/h3-9,17H,2H2,1H3,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50331875
(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(Cl)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C11H5Cl2F3O3/c12-5-1-4-2-6(10(17)18)9(11(14,15)16)19-8(4)7(13)3-5/h1-3,9H,(H,17,18) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336007
(6-chloro-8-(4-(methylsulfonamido)phenyl)-2-(triflu...)Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:18| Show InChI InChI=1S/C18H13ClF3NO5S/c1-29(26,27)23-12-4-2-9(3-5-12)13-8-11(19)6-10-7-14(17(24)25)16(18(20,21)22)28-15(10)13/h2-8,16,23H,1H3,(H,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336016
(6-chloro-8-(4-(ethylthio)phenyl)-2-(trifluoromethy...)Show SMILES CCSc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:16| Show InChI InChI=1S/C19H14ClF3O3S/c1-2-27-13-5-3-10(4-6-13)14-9-12(20)7-11-8-15(18(24)25)17(19(21,22)23)26-16(11)14/h3-9,17H,2H2,1H3,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50331885
(6-chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)...)Show SMILES NS(=O)(=O)c1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:17| Show InChI InChI=1S/C17H11ClF3NO5S/c18-10-5-9-6-13(16(23)24)15(17(19,20)21)27-14(9)12(7-10)8-1-3-11(4-2-8)28(22,25)26/h1-7,15H,(H,23,24)(H2,22,25,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336019
(6-chloro-8-(4-methoxy-3-methylphenyl)-2-(trifluoro...)Show SMILES COc1ccc(cc1C)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:16| Show InChI InChI=1S/C19H14ClF3O4/c1-9-5-10(3-4-15(9)26-2)13-8-12(20)6-11-7-14(18(24)25)17(19(21,22)23)27-16(11)13/h3-8,17H,1-2H3,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336007
(6-chloro-8-(4-(methylsulfonamido)phenyl)-2-(triflu...)Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:18| Show InChI InChI=1S/C18H13ClF3NO5S/c1-29(26,27)23-12-4-2-9(3-5-12)13-8-11(19)6-10-7-14(17(24)25)16(18(20,21)22)28-15(10)13/h2-8,16,23H,1H3,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50336010
(8-(4-carboxyphenyl)-6-chloro-2-(trifluoromethyl)-2...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(-c3ccc(cc3)C(O)=O)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C18H10ClF3O5/c19-11-5-10-6-13(17(25)26)15(18(20,21)22)27-14(10)12(7-11)8-1-3-9(4-2-8)16(23)24/h1-7,15H,(H,23,24)(H,25,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX1 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336010
(8-(4-carboxyphenyl)-6-chloro-2-(trifluoromethyl)-2...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(-c3ccc(cc3)C(O)=O)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C18H10ClF3O5/c19-11-5-10-6-13(17(25)26)15(18(20,21)22)27-14(10)12(7-11)8-1-3-9(4-2-8)16(23)24/h1-7,15H,(H,23,24)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50336011
(6-chloro-8-(4-fluorophenyl)-2-(trifluoromethyl)-2H...)Show SMILES OC(=O)C1=Cc2cc(Cl)cc(-c3ccc(F)cc3)c2OC1C(F)(F)F |t:3| Show InChI InChI=1S/C17H9ClF4O3/c18-10-5-9-6-13(16(23)24)15(17(20,21)22)25-14(9)12(7-10)8-1-3-11(19)4-2-8/h1-7,15H,(H,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem Lett 21: 993-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.023
BindingDB Entry DOI: 10.7270/Q2QR4XDS |
More data for this
Ligand-Target Pair | |
Search and Browse
