Affinity Data by PubMed id=21300543

PubMed code 21300543

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50337676 (2-(4-(2-(1H-pyrazol-4-yl)benzyl)piperazin-1-yl)-5-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	127	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to Bcl-xL after 2 hrs by fluorescein-labeled Bak-BH3 peptide competition binding assay				Bioorg Med Chem Lett 21: 1325-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.054 BindingDB Entry DOI: 10.7270/Q2T153XN
University of the Pacific Curated by ChEMBL					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50337674 (5-benzyl-2-(4-(2-chloro-5-aminobenzyl)piperazin-1-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to Bcl-xL after 2 hrs by fluorescein-labeled Bak-BH3 peptide competition binding assay				Bioorg Med Chem Lett 21: 1325-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.054 BindingDB Entry DOI: 10.7270/Q2T153XN
University of the Pacific Curated by ChEMBL					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50337675 (5-benzyl-2-(4-(3-hydroxybenzyl)piperazin-1-yl)pyri...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to Bcl-xL after 2 hrs by fluorescein-labeled Bak-BH3 peptide competition binding assay				Bioorg Med Chem Lett 21: 1325-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.054 BindingDB Entry DOI: 10.7270/Q2T153XN
University of the Pacific Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%