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PubMed code 21349610

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribonucleoside-diphosphate reductase large subunit/subunit M2


(Homo sapiens (Human))
BDBM50214817
PNG
(CHEMBL236757 | N6-aminoadenosine)
Show SMILES NNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C10H14N6O4/c11-15-8-5-9(13-2-12-8)16(3-14-5)10-7(19)6(18)4(1-17)20-10/h2-4,6-7,10,17-19H,1,11H2,(H,12,13,15)/t4-,6-,7-,10-/m1/s1
PDB
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PC cid
PC sid
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Article
PubMed
n/an/a 2.32E+5n/an/an/an/an/an/a



University of Camerino

Curated by ChEMBL


Assay Description
Inhibition of human recombinant ribonucleotide reductase M2/M1 expressed in Escherichia coli BL21 (DE3) after 30 mins by [3H]CDP reduction method


Eur J Med Chem 46: 1499-504 (2011)


Article DOI: 10.1016/j.ejmech.2011.01.055
BindingDB Entry DOI: 10.7270/Q2K074KT
More data for this
Ligand-Target Pair
Ribonucleoside-diphosphate reductase large subunit/subunit M2 B


(Homo sapiens (Human))
BDBM50214817
PNG
(CHEMBL236757 | N6-aminoadenosine)
Show SMILES NNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C10H14N6O4/c11-15-8-5-9(13-2-12-8)16(3-14-5)10-7(19)6(18)4(1-17)20-10/h2-4,6-7,10,17-19H,1,11H2,(H,12,13,15)/t4-,6-,7-,10-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.44E+5n/an/an/an/an/an/a



University of Camerino

Curated by ChEMBL


Assay Description
Inhibition of human recombinant ribonucleotide reductase p53R2/M1 expressed in Escherichia coli BL21 (DE3) after 30 mins by [3H]CDP reduction method


Eur J Med Chem 46: 1499-504 (2011)


Article DOI: 10.1016/j.ejmech.2011.01.055
BindingDB Entry DOI: 10.7270/Q2K074KT
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%