Affinity Data by PubMed id=21417236

PubMed code 21417236

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis)	BDBM50343344 (1-(thiophen-2-ylacetyl)-4-(3-thiophen-2-yl-1,2,4-o...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Lille Nord de France Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assay				J Med Chem 54: 2994-3010 (2011) Article DOI: 10.1021/jm200076a BindingDB Entry DOI: 10.7270/Q2SJ1KXS
Universit£ Lille Nord de France Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis)	BDBM50343346 (4-Methyl-1-[4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-y...) Show SMILES CC(C)CCC(=O)N1CCC(CC1)c1nc(no1)-c1cccs1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Lille Nord de France Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assay				J Med Chem 54: 2994-3010 (2011) Article DOI: 10.1021/jm200076a BindingDB Entry DOI: 10.7270/Q2SJ1KXS
Universit£ Lille Nord de France Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis)	BDBM50343347 (2-Cyclopropyl-1-[4-(3-thiophen-2-yl-[1,2,4]oxadiaz...) Show SMILES O=C(CC1CC1)N1CCC(CC1)c1nc(no1)-c1cccs1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Lille Nord de France Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assay				J Med Chem 54: 2994-3010 (2011) Article DOI: 10.1021/jm200076a BindingDB Entry DOI: 10.7270/Q2SJ1KXS
Universit£ Lille Nord de France Curated by ChEMBL					More data for this Ligand-Target Pair
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis)	BDBM50343348 (2-Cyclopentyl-1-[4-(3-thiophen-2-yl-[1,2,4]oxadiaz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Lille Nord de France Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assay				J Med Chem 54: 2994-3010 (2011) Article DOI: 10.1021/jm200076a BindingDB Entry DOI: 10.7270/Q2SJ1KXS
Universit£ Lille Nord de France Curated by ChEMBL					More data for this Ligand-Target Pair
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis)	BDBM50343350 (4,4,4-trifluoro-1-(4-(3-(thiophen-2-yl)-1,2,4-oxad...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Lille Nord de France Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assay				J Med Chem 54: 2994-3010 (2011) Article DOI: 10.1021/jm200076a BindingDB Entry DOI: 10.7270/Q2SJ1KXS
Universit£ Lille Nord de France Curated by ChEMBL					More data for this Ligand-Target Pair
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis)	BDBM50343351 (4,4,4-Trifluoro-1-[(R)-3-(3-thiophen-2-yl-1,2,4-ox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Lille Nord de France Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assay				J Med Chem 54: 2994-3010 (2011) Article DOI: 10.1021/jm200076a BindingDB Entry DOI: 10.7270/Q2SJ1KXS
Universit£ Lille Nord de France Curated by ChEMBL					More data for this Ligand-Target Pair
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis)	BDBM50343349 (2-Cyclohexyl-1-[4-(3-thiophen-2-yl-[1,2,4]oxadiazo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Lille Nord de France Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assay				J Med Chem 54: 2994-3010 (2011) Article DOI: 10.1021/jm200076a BindingDB Entry DOI: 10.7270/Q2SJ1KXS
Universit£ Lille Nord de France Curated by ChEMBL					More data for this Ligand-Target Pair
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis)	BDBM50343345 (2-Phenyl-1-[4-(3-thiophen-2-yl-[1,2,4]oxadiazol-5-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Lille Nord de France Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assay				J Med Chem 54: 2994-3010 (2011) Article DOI: 10.1021/jm200076a BindingDB Entry DOI: 10.7270/Q2SJ1KXS
Universit£ Lille Nord de France Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%