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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50172899 (3,4-diarylpyrazoline derivative | CHEMBL195050) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of radioligand CP55940 from human CB1 receptor expressed in CHO cells by radioligand binding assay | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50172900 (3,4-diarylpyrazoline derivative | CHEMBL197040) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 155 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of radioligand CP55940 from human CB1 receptor expressed in CHO cells by radioligand binding assay | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50172909 (3,4-diarylpyrazoline derivative | CHEMBL372650) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 223 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of radioligand CP55940 from human CB1 receptor expressed in CHO cells by radioligand binding assay | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50172904 (3,4-diarylpyrazoline derivative | CHEMBL196989) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 231 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Displacement of radioligand CP55940 from human CB1 receptor expressed in CHO cells by radioligand binding assay | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Multidrug resistance-associated protein 1 (Homo sapiens (Human)) | BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Noncompetitive inhibition of MRP1-mediated E2-17betaG transport in human MRP1 expressing HEK293 cells by Dixon plot | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ATP-binding cassette sub-family C member 4 (Homo sapiens (Human)) | BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Noncompetitive inhibition of MRP4-mediated E2-17betaG transport in human MRP4 expressing HEK293 cells by Dixon plot | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ATP-binding cassette sub-family C member 4 (Homo sapiens (Human)) | BDBM50172903 (3,4-diarylpyrazoline derivative | CHEMBL364300) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Nijmegen Medical Centre Curated by ChEMBL | Assay Description Noncompetitive inhibition of MRP4-mediated E2-17betaG transport in human MRP4 expressing HEK293 cells by Dixon plot | Drug Metab Dispos 39: 1294-302 (2011) Article DOI: 10.1124/dmd.110.037812 BindingDB Entry DOI: 10.7270/Q2MK6FMS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
