Found 35 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cholecystokinin receptor type A
(RAT) | BDBM50418901
(CHEMBL1808415)Show SMILES Cc1cccc(NC(=O)NC2C(=O)N(CCN3CCOCC3)c3ccccc3N(CC3CCCCC3)C2=O)c1 Show InChI InChI=1S/C30H39N5O4/c1-22-8-7-11-24(20-22)31-30(38)32-27-28(36)34(15-14-33-16-18-39-19-17-33)25-12-5-6-13-26(25)35(29(27)37)21-23-9-3-2-4-10-23/h5-8,11-13,20,23,27H,2-4,9-10,14-19,21H2,1H3,(H2,31,32,38) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 174 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418893
(CHEMBL1808400)Show SMILES CC(C)CCN1c2ccccc2N(CCN2CCOCC2)C(=O)C(NC(=O)Nc2cccc(C)c2)C1=O Show InChI InChI=1S/C28H37N5O4/c1-20(2)11-12-32-23-9-4-5-10-24(23)33(14-13-31-15-17-37-18-16-31)27(35)25(26(32)34)30-28(36)29-22-8-6-7-21(3)19-22/h4-10,19-20,25H,11-18H2,1-3H3,(H2,29,30,36) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 275 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418884
(CHEMBL1808414)Show SMILES O=C(NC1C(=O)N(CCN2CCOCC2)c2ccccc2N(CC2CCCCC2)C1=O)Nc1ccccc1 Show InChI InChI=1S/C29H37N5O4/c35-27-26(31-29(37)30-23-11-5-2-6-12-23)28(36)34(21-22-9-3-1-4-10-22)25-14-8-7-13-24(25)33(27)16-15-32-17-19-38-20-18-32/h2,5-8,11-14,22,26H,1,3-4,9-10,15-21H2,(H2,30,31,37) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 347 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418896
(CHEMBL1807152)Show SMILES CCN(CC)CCN1c2ccccc2N(CC2CCCCC2)C(=O)C(NC(=O)Nc2ccccc2)C1=O Show InChI InChI=1S/C29H39N5O3/c1-3-32(4-2)19-20-33-24-17-11-12-18-25(24)34(21-22-13-7-5-8-14-22)28(36)26(27(33)35)31-29(37)30-23-15-9-6-10-16-23/h6,9-12,15-18,22,26H,3-5,7-8,13-14,19-21H2,1-2H3,(H2,30,31,37) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 467 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418896
(CHEMBL1807152)Show SMILES CCN(CC)CCN1c2ccccc2N(CC2CCCCC2)C(=O)C(NC(=O)Nc2ccccc2)C1=O Show InChI InChI=1S/C29H39N5O3/c1-3-32(4-2)19-20-33-24-17-11-12-18-25(24)34(21-22-13-7-5-8-14-22)28(36)26(27(33)35)31-29(37)30-23-15-9-6-10-16-23/h6,9-12,15-18,22,26H,3-5,7-8,13-14,19-21H2,1-2H3,(H2,30,31,37) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 468 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418891
(CHEMBL1808405)Show SMILES CC(C)CCN1c2ccccc2N(CCN2CCOCC2)C(=O)C(NC(=O)Nc2ccc(Br)cc2C)C1=O Show InChI InChI=1S/C28H36BrN5O4/c1-19(2)10-11-33-23-6-4-5-7-24(23)34(13-12-32-14-16-38-17-15-32)27(36)25(26(33)35)31-28(37)30-22-9-8-21(29)18-20(22)3/h4-9,18-19,25H,10-17H2,1-3H3,(H2,30,31,37) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 537 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418898
(CHEMBL1808398)Show SMILES CC(C)CCN1c2ccccc2N(CCN2CCOCC2)C(=O)C(NC(=O)Nc2ccccc2)C1=O Show InChI InChI=1S/C27H35N5O4/c1-20(2)12-13-31-22-10-6-7-11-23(22)32(15-14-30-16-18-36-19-17-30)26(34)24(25(31)33)29-27(35)28-21-8-4-3-5-9-21/h3-11,20,24H,12-19H2,1-2H3,(H2,28,29,35) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 676 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418878
(CHEMBL1808418)Show SMILES Fc1ccc(NC(=O)NC2C(=O)N(CCN3CCOCC3)c3ccccc3N(CC34CC5CC(CC(C5)C3)C4)C2=O)cc1 |TLB:38:29:36:33.32.34,28:29:32:36.35.34,THB:38:33:36:29.37.30,37:35:32:38.29.30,37:29:32:36.35.34| Show InChI InChI=1S/C33H40FN5O4/c34-25-5-7-26(8-6-25)35-32(42)36-29-30(40)38(10-9-37-11-13-43-14-12-37)27-3-1-2-4-28(27)39(31(29)41)21-33-18-22-15-23(19-33)17-24(16-22)20-33/h1-8,22-24,29H,9-21H2,(H2,35,36,42) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418894
(CHEMBL1808399)Show SMILES CC(C)CCN1c2ccccc2N(CCN2CCOCC2)C(=O)C(NC(=O)Nc2ccc(Cl)cc2)C1=O Show InChI InChI=1S/C27H34ClN5O4/c1-19(2)11-12-32-22-5-3-4-6-23(22)33(14-13-31-15-17-37-18-16-31)26(35)24(25(32)34)30-27(36)29-21-9-7-20(28)8-10-21/h3-10,19,24H,11-18H2,1-2H3,(H2,29,30,36) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418897
(CHEMBL1808402)Show SMILES CC(C)CCN1c2ccccc2N(CCN2CCOCC2)C(=O)C(NC(=O)Nc2ccc(Br)cc2)C1=O Show InChI InChI=1S/C27H34BrN5O4/c1-19(2)11-12-32-22-5-3-4-6-23(22)33(14-13-31-15-17-37-18-16-31)26(35)24(25(32)34)30-27(36)29-21-9-7-20(28)8-10-21/h3-10,19,24H,11-18H2,1-2H3,(H2,29,30,36) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418892
(CHEMBL1808403)Show SMILES CC(C)CCN1c2ccccc2N(CCN2CCOCC2)C(=O)C(NC(=O)Nc2ccc(F)cc2)C1=O Show InChI InChI=1S/C27H34FN5O4/c1-19(2)11-12-32-22-5-3-4-6-23(22)33(14-13-31-15-17-37-18-16-31)26(35)24(25(32)34)30-27(36)29-21-9-7-20(28)8-10-21/h3-10,19,24H,11-18H2,1-2H3,(H2,29,30,36) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418904
(CHEMBL1808401)Show SMILES CC(C)CCN1c2ccccc2N(CCN2CCOCC2)C(=O)C(NC(=O)Nc2ccc(cc2)C(F)(F)F)C1=O Show InChI InChI=1S/C28H34F3N5O4/c1-19(2)11-12-35-22-5-3-4-6-23(22)36(14-13-34-15-17-40-18-16-34)26(38)24(25(35)37)33-27(39)32-21-9-7-20(8-10-21)28(29,30)31/h3-10,19,24H,11-18H2,1-2H3,(H2,32,33,39) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418880
(CHEMBL1808416)Show SMILES O=C(NC1C(=O)N(CCN2CCOCC2)c2ccccc2N(CC23CC4CC(CC(C4)C2)C3)C1=O)Nc1ccccc1 |TLB:32:23:30:27.26.28,22:23:26:30.29.28,THB:32:27:30:23.31.24,31:29:26:32.23.24,31:23:26:30.29.28| Show InChI InChI=1S/C33H41N5O4/c39-30-29(35-32(41)34-26-6-2-1-3-7-26)31(40)38(22-33-19-23-16-24(20-33)18-25(17-23)21-33)28-9-5-4-8-27(28)37(30)11-10-36-12-14-42-15-13-36/h1-9,23-25,29H,10-22H2,(H2,34,35,41) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418880
(CHEMBL1808416)Show SMILES O=C(NC1C(=O)N(CCN2CCOCC2)c2ccccc2N(CC23CC4CC(CC(C4)C2)C3)C1=O)Nc1ccccc1 |TLB:32:23:30:27.26.28,22:23:26:30.29.28,THB:32:27:30:23.31.24,31:29:26:32.23.24,31:23:26:30.29.28| Show InChI InChI=1S/C33H41N5O4/c39-30-29(35-32(41)34-26-6-2-1-3-7-26)31(40)38(22-33-19-23-16-24(20-33)18-25(17-23)21-33)28-9-5-4-8-27(28)37(30)11-10-36-12-14-42-15-13-36/h1-9,23-25,29H,10-22H2,(H2,34,35,41) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418880
(CHEMBL1808416)Show SMILES O=C(NC1C(=O)N(CCN2CCOCC2)c2ccccc2N(CC23CC4CC(CC(C4)C2)C3)C1=O)Nc1ccccc1 |TLB:32:23:30:27.26.28,22:23:26:30.29.28,THB:32:27:30:23.31.24,31:29:26:32.23.24,31:23:26:30.29.28| Show InChI InChI=1S/C33H41N5O4/c39-30-29(35-32(41)34-26-6-2-1-3-7-26)31(40)38(22-33-19-23-16-24(20-33)18-25(17-23)21-33)28-9-5-4-8-27(28)37(30)11-10-36-12-14-42-15-13-36/h1-9,23-25,29H,10-22H2,(H2,34,35,41) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418881
(CHEMBL1808422)Show SMILES CCN(CC)CCN1c2ccccc2N(CC23CC4CC(CC(C4)C2)C3)C(=O)C(NC(=O)Nc2ccc(F)cc2)C1=O |TLB:25:16:23:20.19.21,15:16:19:23.22.21,THB:25:20:23:16.24.17,24:22:19:25.16.17,24:16:19:23.22.21| Show InChI InChI=1S/C33H42FN5O3/c1-3-37(4-2)13-14-38-27-7-5-6-8-28(27)39(21-33-18-22-15-23(19-33)17-24(16-22)20-33)31(41)29(30(38)40)36-32(42)35-26-11-9-25(34)10-12-26/h5-12,22-24,29H,3-4,13-21H2,1-2H3,(H2,35,36,42) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418887
(CHEMBL1808410)Show SMILES CC(C)CCN1c2ccccc2N(CCN2CCCCC2)C(=O)C(NC(=O)Nc2ccccc2)C1=O Show InChI InChI=1S/C28H37N5O3/c1-21(2)15-18-32-23-13-7-8-14-24(23)33(20-19-31-16-9-4-10-17-31)27(35)25(26(32)34)30-28(36)29-22-11-5-3-6-12-22/h3,5-8,11-14,21,25H,4,9-10,15-20H2,1-2H3,(H2,29,30,36) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418879
(CHEMBL1808417)Show SMILES Fc1ccc2N(CC34CC5CC(CC(C5)C3)C4)C(=O)C(NC(=O)Nc3ccccc3)C(=O)N(CCN3CCOCC3)c2c1 |TLB:16:7:14:11.10.12,6:7:10:14.13.12,THB:16:11:14:7.15.8,15:13:10:16.7.8,15:7:10:14.13.12| Show InChI InChI=1S/C33H40FN5O4/c34-25-6-7-27-28(17-25)38(9-8-37-10-12-43-13-11-37)30(40)29(36-32(42)35-26-4-2-1-3-5-26)31(41)39(27)21-33-18-22-14-23(19-33)16-24(15-22)20-33/h1-7,17,22-24,29H,8-16,18-21H2,(H2,35,36,42) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418879
(CHEMBL1808417)Show SMILES Fc1ccc2N(CC34CC5CC(CC(C5)C3)C4)C(=O)C(NC(=O)Nc3ccccc3)C(=O)N(CCN3CCOCC3)c2c1 |TLB:16:7:14:11.10.12,6:7:10:14.13.12,THB:16:11:14:7.15.8,15:13:10:16.7.8,15:7:10:14.13.12| Show InChI InChI=1S/C33H40FN5O4/c34-25-6-7-27-28(17-25)38(9-8-37-10-12-43-13-11-37)30(40)29(36-32(42)35-26-4-2-1-3-5-26)31(41)39(27)21-33-18-22-14-23(19-33)16-24(15-22)20-33/h1-7,17,22-24,29H,8-16,18-21H2,(H2,35,36,42) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418878
(CHEMBL1808418)Show SMILES Fc1ccc(NC(=O)NC2C(=O)N(CCN3CCOCC3)c3ccccc3N(CC34CC5CC(CC(C5)C3)C4)C2=O)cc1 |TLB:38:29:36:33.32.34,28:29:32:36.35.34,THB:38:33:36:29.37.30,37:35:32:38.29.30,37:29:32:36.35.34| Show InChI InChI=1S/C33H40FN5O4/c34-25-5-7-26(8-6-25)35-32(42)36-29-30(40)38(10-9-37-11-13-43-14-12-37)27-3-1-2-4-28(27)39(31(29)41)21-33-18-22-15-23(19-33)17-24(16-22)20-33/h1-8,22-24,29H,9-21H2,(H2,35,36,42) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418878
(CHEMBL1808418)Show SMILES Fc1ccc(NC(=O)NC2C(=O)N(CCN3CCOCC3)c3ccccc3N(CC34CC5CC(CC(C5)C3)C4)C2=O)cc1 |TLB:38:29:36:33.32.34,28:29:32:36.35.34,THB:38:33:36:29.37.30,37:35:32:38.29.30,37:29:32:36.35.34| Show InChI InChI=1S/C33H40FN5O4/c34-25-5-7-26(8-6-25)35-32(42)36-29-30(40)38(10-9-37-11-13-43-14-12-37)27-3-1-2-4-28(27)39(31(29)41)21-33-18-22-15-23(19-33)17-24(16-22)20-33/h1-8,22-24,29H,9-21H2,(H2,35,36,42) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418896
(CHEMBL1807152)Show SMILES CCN(CC)CCN1c2ccccc2N(CC2CCCCC2)C(=O)C(NC(=O)Nc2ccccc2)C1=O Show InChI InChI=1S/C29H39N5O3/c1-3-32(4-2)19-20-33-24-17-11-12-18-25(24)34(21-22-13-7-5-8-14-22)28(36)26(27(33)35)31-29(37)30-23-15-9-6-10-16-23/h6,9-12,15-18,22,26H,3-5,7-8,13-14,19-21H2,1-2H3,(H2,30,31,37) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418879
(CHEMBL1808417)Show SMILES Fc1ccc2N(CC34CC5CC(CC(C5)C3)C4)C(=O)C(NC(=O)Nc3ccccc3)C(=O)N(CCN3CCOCC3)c2c1 |TLB:16:7:14:11.10.12,6:7:10:14.13.12,THB:16:11:14:7.15.8,15:13:10:16.7.8,15:7:10:14.13.12| Show InChI InChI=1S/C33H40FN5O4/c34-25-6-7-27-28(17-25)38(9-8-37-10-12-43-13-11-37)30(40)29(36-32(42)35-26-4-2-1-3-5-26)31(41)39(27)21-33-18-22-14-23(19-33)16-24(15-22)20-33/h1-7,17,22-24,29H,8-16,18-21H2,(H2,35,36,42) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418883
(CHEMBL1808420)Show SMILES CN(C)CCN1c2ccccc2N(CC23CC4CC(CC(C4)C2)C3)C(=O)C(NC(=O)Nc2ccccc2)C1=O |TLB:23:14:21:18.17.19,13:14:17:21.20.19,THB:23:18:21:14.22.15,22:20:17:23.14.15,22:14:17:21.20.19| Show InChI InChI=1S/C31H39N5O3/c1-34(2)12-13-35-25-10-6-7-11-26(25)36(20-31-17-21-14-22(18-31)16-23(15-21)19-31)29(38)27(28(35)37)33-30(39)32-24-8-4-3-5-9-24/h3-11,21-23,27H,12-20H2,1-2H3,(H2,32,33,39) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418886
(CHEMBL1808411)Show SMILES CC(C)CCN1c2ccccc2N(CCN(C)C)C(=O)C(NC(=O)Nc2ccccc2)C1=O Show InChI InChI=1S/C25H33N5O3/c1-18(2)14-15-29-20-12-8-9-13-21(20)30(17-16-28(3)4)24(32)22(23(29)31)27-25(33)26-19-10-6-5-7-11-19/h5-13,18,22H,14-17H2,1-4H3,(H2,26,27,33) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418899
(CHEMBL1808413)Show SMILES CCN(CC)CCN1c2ccccc2N(CCC(C)C)C(=O)C(NC(=O)Nc2ccccc2)C1=O Show InChI InChI=1S/C27H37N5O3/c1-5-30(6-2)18-19-32-23-15-11-10-14-22(23)31(17-16-20(3)4)25(33)24(26(32)34)29-27(35)28-21-12-8-7-9-13-21/h7-15,20,24H,5-6,16-19H2,1-4H3,(H2,28,29,35) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418889
(CHEMBL1808407)Show SMILES CC(C)CCN1c2ccccc2N(CCN2CCOCC2)C(=O)C(NC(=O)Nc2c(C)cccc2Cl)C1=O Show InChI InChI=1S/C28H36ClN5O4/c1-19(2)11-12-33-22-9-4-5-10-23(22)34(14-13-32-15-17-38-18-16-32)27(36)25(26(33)35)31-28(37)30-24-20(3)7-6-8-21(24)29/h4-10,19,25H,11-18H2,1-3H3,(H2,30,31,37) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418888
(CHEMBL1808408)Show SMILES COc1ccc(NC(=O)NC2C(=O)N(CCC(C)C)c3ccccc3N(CCN3CCOCC3)C2=O)cc1 Show InChI InChI=1S/C28H37N5O5/c1-20(2)12-13-32-23-6-4-5-7-24(23)33(15-14-31-16-18-38-19-17-31)27(35)25(26(32)34)30-28(36)29-21-8-10-22(37-3)11-9-21/h4-11,20,25H,12-19H2,1-3H3,(H2,29,30,36) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418890
(CHEMBL1806517)Show SMILES COc1ccc(NC(=O)NC2C(=O)N(CCC(C)C)c3ccccc3N(CCN3CCOCC3)C2=O)c(C)c1 Show InChI InChI=1S/C29H39N5O5/c1-20(2)11-12-33-24-7-5-6-8-25(24)34(14-13-32-15-17-39-18-16-32)28(36)26(27(33)35)31-29(37)30-23-10-9-22(38-4)19-21(23)3/h5-10,19-20,26H,11-18H2,1-4H3,(H2,30,31,37) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418902
(CHEMBL1808409)Show SMILES CC(C)CCN1c2ccccc2N(CCN2CCOCC2)C(=O)C(NC(=O)Nc2ccc(O)cc2)C1=O Show InChI InChI=1S/C27H35N5O5/c1-19(2)11-12-31-22-5-3-4-6-23(22)32(14-13-30-15-17-37-18-16-30)26(35)24(25(31)34)29-27(36)28-20-7-9-21(33)10-8-20/h3-10,19,24,33H,11-18H2,1-2H3,(H2,28,29,36) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418900
(CHEMBL1808419)Show SMILES O=C(NC1C(=O)N(CCN2CCCC2)c2ccccc2N(CC23CC4CC(CC(C4)C2)C3)C1=O)Nc1ccccc1 |TLB:31:22:29:26.25.27,21:22:25:29.28.27,THB:31:26:29:22.30.23,30:28:25:31.22.23,30:22:25:29.28.27| Show InChI InChI=1S/C33H41N5O3/c39-30-29(35-32(41)34-26-8-2-1-3-9-26)31(40)38(22-33-19-23-16-24(20-33)18-25(17-23)21-33)28-11-5-4-10-27(28)37(30)15-14-36-12-6-7-13-36/h1-5,8-11,23-25,29H,6-7,12-22H2,(H2,34,35,41) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 9.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418903
(CHEMBL1808406)Show SMILES CC(C)CCN1c2ccccc2N(CCN2CCOCC2)C(=O)C(NC(=O)Nc2ccccc2C(C)C)C1=O Show InChI InChI=1S/C30H41N5O4/c1-21(2)13-14-34-25-11-7-8-12-26(25)35(16-15-33-17-19-39-20-18-33)29(37)27(28(34)36)32-30(38)31-24-10-6-5-9-23(24)22(3)4/h5-12,21-22,27H,13-20H2,1-4H3,(H2,31,32,38) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418895
(CHEMBL1808404)Show SMILES CCOc1ccc(NC(=O)NC2C(=O)N(CCC(C)C)c3ccccc3N(CCN3CCOCC3)C2=O)cc1 Show InChI InChI=1S/C29H39N5O5/c1-4-39-23-11-9-22(10-12-23)30-29(37)31-26-27(35)33(14-13-21(2)3)24-7-5-6-8-25(24)34(28(26)36)16-15-32-17-19-38-20-18-32/h5-12,21,26H,4,13-20H2,1-3H3,(H2,30,31,37) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418885
(CHEMBL1808412)Show SMILES COc1ccc(NC(=O)NC2C(=O)N(CCC(C)C)c3ccccc3N(CCN(C)C)C2=O)cc1 Show InChI InChI=1S/C26H35N5O4/c1-18(2)14-15-30-21-8-6-7-9-22(21)31(17-16-29(3)4)25(33)23(24(30)32)28-26(34)27-19-10-12-20(35-5)13-11-19/h6-13,18,23H,14-17H2,1-5H3,(H2,27,28,34) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.74E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |
Cholecystokinin receptor type A
(RAT) | BDBM50418882
(CHEMBL1808421)Show SMILES CN(C)CCCN1c2ccccc2N(CC23CC4CC(CC(C4)C2)C3)C(=O)C(NC(=O)Nc2ccccc2)C1=O |TLB:24:15:22:19.18.20,14:15:18:22.21.20,THB:24:19:22:15.23.16,23:21:18:24.15.16,23:15:18:22.21.20| Show InChI InChI=1S/C32H41N5O3/c1-35(2)13-8-14-36-26-11-6-7-12-27(26)37(21-32-18-22-15-23(19-32)17-24(16-22)20-32)30(39)28(29(36)38)34-31(40)33-25-9-4-3-5-10-25/h3-7,9-12,22-24,28H,8,13-21H2,1-2H3,(H2,33,34,40) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]CCK8 from rat pancreas CCK1 receptor at by liquid scintillation counting |
Bioorg Med Chem 19: 4257-73 (2011)
Article DOI: 10.1016/j.bmc.2011.05.057 BindingDB Entry DOI: 10.7270/Q2416Z93 |
More data for this Ligand-Target Pair | |