Affinity Data by PubMed id=21782425

PubMed code 21782425

Found 21 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM26646 ((5Z)-5-[(3-bromophenyl)methylidene]-1,3-thiazolidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50340098 (5-(4-hydroxy-3-methoxybenzylidene)-2-thioxothiazol...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50352038 (CHEMBL1823806) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50324735 ((5E)-5-(QUINOXALIN-6-YLMETHYLENE)-1,3-THIAZOLIDINE...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50322615 (CHEMBL1173685 \| CHEMBL1823816 \| Resveratrol Potass...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50350492 (CHEMBL1814643) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50350502 (CHEMBL1814651) Show SMILES CN1C(=S)S\C(=C\c2ccc(Cl)cc2)C1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50352037 (CHEMBL1823804) Show SMILES Oc1[nH]c(=O)sc1Cc1ccc2OC(F)(F)Oc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50350504 (CHEMBL1814639) Show SMILES SC1=NC(=O)C(S1)=Cc1ccncc1 \|w:7.8,t:1\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50350486 (CHEMBL602048) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50350487 (CHEMBL1814635) Show SMILES Cc1cc(Cc2sc(=O)[nH]c2O)cc(C)c1O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50350490 (CHEMBL1814638) Show SMILES OC(=O)CCN1C(=S)S\C(=C\c2ccccc2)C1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50350497 (CHEMBL1814649) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50350499 (CHEMBL1814636) Show SMILES Cc1cc(C)cc(Cc2sc(=O)[nH]c2O)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50350489 (CHEMBL1814637) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50350488 (CHEMBL1061) Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50350498 (CHEMBL1814650) Show SMILES CN1C(=S)S\C(=C\c2ccccc2)C1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50352035 (CHEMBL1823809) Show SMILES CCCN1C(=O)S\C(=C\c2ccncc2)C1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50350501 (CHEMBL1814642) Show SMILES OC1=NC(=O)C(S1)=Cc1ccncc1 \|w:7.8,t:1\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50324736 (3-(2-aminoethyl)-5-(2-methoxybenzylidene)thiazolid...) Show SMILES COc1ccccc1\C=C1/SC(=O)N(CCN)C1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Homo sapiens (Human))	BDBM50350491 (CHEMBL1814641) Show SMILES Nc1nc(O)c(Cc2ccccc2)s1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.73E+7	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...				Bioorg Med Chem Lett 21: 5498-501 (2011) Article DOI: 10.1016/j.bmcl.2011.06.111 BindingDB Entry DOI: 10.7270/Q2T43TFB
Northeast Ohio Medical University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%