Affinity Data by PubMed id=21840712

PubMed code 21840712

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Branched-chain-amino-acid aminotransferase, cytosolic (Homo sapiens (Human))	BDBM50353005 (CHEMBL1231666) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant histidine-tagged BCATc expressed in Escherichia coli BL21 (DE3) after 50 mins using [13C]-L-leucine as substrate by N...				Bioorg Med Chem Lett 21: 5248-50 (2011) Article DOI: 10.1016/j.bmcl.2011.07.039 BindingDB Entry DOI: 10.7270/Q2CR5TR9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Branched-chain-amino-acid aminotransferase, cytosolic (Homo sapiens (Human))	BDBM50353006 (CHEMBL1825195) Show SMILES Fc1cccc(-c2oncc2C#N)c1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant histidine-tagged BCATc expressed in Escherichia coli BL21 (DE3) after 50 mins using [13C]-L-leucine as substrate by N...				Bioorg Med Chem Lett 21: 5248-50 (2011) Article DOI: 10.1016/j.bmcl.2011.07.039 BindingDB Entry DOI: 10.7270/Q2CR5TR9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Branched-chain-amino-acid aminotransferase, cytosolic (Homo sapiens (Human))	BDBM50353007 (CHEMBL1825196) Show SMILES CC(=O)NNS(=O)(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant histidine-tagged BCATc expressed in Escherichia coli BL21 (DE3) after 50 mins using [13C]-L-leucine as substrate by N...				Bioorg Med Chem Lett 21: 5248-50 (2011) Article DOI: 10.1016/j.bmcl.2011.07.039 BindingDB Entry DOI: 10.7270/Q2CR5TR9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Branched-chain-amino-acid aminotransferase, cytosolic (Homo sapiens (Human))	BDBM50353008 (CHEMBL1825197) Show SMILES C#CCSc1nnc(o1)-c1cccs1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant histidine-tagged BCATc expressed in Escherichia coli BL21 (DE3) after 50 mins using [13C]-L-leucine as substrate by N...				Bioorg Med Chem Lett 21: 5248-50 (2011) Article DOI: 10.1016/j.bmcl.2011.07.039 BindingDB Entry DOI: 10.7270/Q2CR5TR9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Branched-chain-amino-acid aminotransferase, cytosolic (Homo sapiens (Human))	BDBM50353009 (CHEMBL1825198) Show SMILES CN(C)\C=N\NS(=O)(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant histidine-tagged BCATc expressed in Escherichia coli BL21 (DE3) after 50 mins using [13C]-L-leucine as substrate by N...				Bioorg Med Chem Lett 21: 5248-50 (2011) Article DOI: 10.1016/j.bmcl.2011.07.039 BindingDB Entry DOI: 10.7270/Q2CR5TR9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Branched-chain-amino-acid aminotransferase, cytosolic (Homo sapiens (Human))	BDBM50353010 (CHEMBL1825199) Show SMILES O=c1n(nc(C#N)c2ccccc12)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant histidine-tagged BCATc expressed in Escherichia coli BL21 (DE3) after 50 mins using [13C]-L-leucine as substrate by N...				Bioorg Med Chem Lett 21: 5248-50 (2011) Article DOI: 10.1016/j.bmcl.2011.07.039 BindingDB Entry DOI: 10.7270/Q2CR5TR9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Branched-chain-amino-acid aminotransferase, cytosolic (Homo sapiens (Human))	BDBM50353011 (CHEMBL1825200) Show SMILES Clc1cc(=O)n(nc1C#N)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant histidine-tagged BCATc expressed in Escherichia coli BL21 (DE3) after 50 mins using [13C]-L-leucine as substrate by N...				Bioorg Med Chem Lett 21: 5248-50 (2011) Article DOI: 10.1016/j.bmcl.2011.07.039 BindingDB Entry DOI: 10.7270/Q2CR5TR9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%