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PubMed code 21906954

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thromboxane A2 receptor


(Homo sapiens (Human))
BDBM50353899
PNG
(CHEMBL1829095)
Show SMILES NC(=O)c1c(CSCC(=O)Oc2ccccc2C(O)=O)no[n+]1[O-]
Show InChI InChI=1S/C13H11N3O7S/c14-12(18)11-8(15-23-16(11)21)5-24-6-10(17)22-9-4-2-1-3-7(9)13(19)20/h1-4H,5-6H2,(H2,14,18)(H,19,20)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.80E+4n/an/an/an/an/an/a



Universit£ degli Studi di Torino

Curated by ChEMBL


Assay Description
Antagonist activity at thromboxane receptor in human blood assessed as inhibition of U-46619-induced effect


Bioorg Med Chem 19: 5852-60 (2011)


Article DOI: 10.1016/j.bmc.2011.08.018
BindingDB Entry DOI: 10.7270/Q29P321Q
More data for this
Ligand-Target Pair
Thromboxane A2 receptor


(Homo sapiens (Human))
BDBM50353898
PNG
(CHEMBL1829096)
Show SMILES NC(=O)c1nonc1CSCC(=O)Oc1ccccc1C(O)=O
Show InChI InChI=1S/C13H11N3O6S/c14-12(18)11-8(15-22-16-11)5-23-6-10(17)21-9-4-2-1-3-7(9)13(19)20/h1-4H,5-6H2,(H2,14,18)(H,19,20)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.90E+4n/an/an/an/an/an/a



Universit£ degli Studi di Torino

Curated by ChEMBL


Assay Description
Antagonist activity at thromboxane receptor in human blood assessed as inhibition of U-46619-induced effect


Bioorg Med Chem 19: 5852-60 (2011)


Article DOI: 10.1016/j.bmc.2011.08.018
BindingDB Entry DOI: 10.7270/Q29P321Q
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%