| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50353899 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_769673 (CHEMBL1831444) |
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| IC50 | 38000±n/a nM |
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| Citation |  Lazzarato, L; Cena, C; Rolando, B; Marini, E; Lolli, ML; Guglielmo, S; Guaita, E; Morini, G; Coruzzi, G; Fruttero, R; Gasco, A Searching for new NO-donor aspirin-like molecules: Furoxanylacyl derivatives of salicylic acid and related furazans. Bioorg Med Chem19:5852-60 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
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| Type: | Enyzme |
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| Mol. Mass.: | 37445.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21731 |
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| Residue: | 343 |
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| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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| BDBM50353899 |
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| n/a |
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| Name | BDBM50353899 |
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| Synonyms: | CHEMBL1829095 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H11N3O7S |
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| Mol. Mass. | 353.307 |
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| SMILES | NC(=O)c1c(CSCC(=O)Oc2ccccc2C(O)=O)no[n+]1[O-] |
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| Structure | 
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