Found 40 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM23971
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 5.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353911
(CHEMBL1830651)Show SMILES ONC(=O)[C@@H](NC(=O)[C@@H]1Cc2ccccc2CN1)c1ccccc1 |r| Show InChI InChI=1S/C18H19N3O3/c22-17(15-10-13-8-4-5-9-14(13)11-19-15)20-16(18(23)21-24)12-6-2-1-3-7-12/h1-9,15-16,19,24H,10-11H2,(H,20,22)(H,21,23)/t15-,16-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353915
(CHEMBL1830654)Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C15H21N3O3S/c1-22-7-6-12(15(20)18-21)17-14(19)13-8-10-4-2-3-5-11(10)9-16-13/h2-5,12-13,16,21H,6-9H2,1H3,(H,17,19)(H,18,20)/t12-,13-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353914
(CHEMBL1830653)Show SMILES ONC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1Cc2ccccc2CN1 |r| Show InChI InChI=1S/C19H21N3O4/c23-15-7-5-12(6-8-15)9-17(19(25)22-26)21-18(24)16-10-13-3-1-2-4-14(13)11-20-16/h1-8,16-17,20,23,26H,9-11H2,(H,21,24)(H,22,25)/t16-,17-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353912
(CHEMBL1830652)Show SMILES ONC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2ccccc2CN1 |r| Show InChI InChI=1S/C19H21N3O3/c23-18(16-11-14-8-4-5-9-15(14)12-20-16)21-17(19(24)22-25)10-13-6-2-1-3-7-13/h1-9,16-17,20,25H,10-12H2,(H,21,23)(H,22,24)/t16-,17-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353921
(CHEMBL1830659)Show SMILES ONC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)[C@@H]1Cc2ccccc2CN1 |r| Show InChI InChI=1S/C23H28N4O5/c28-21(20-13-17-9-4-5-10-18(17)14-25-20)26-19(22(29)27-31)11-6-12-24-23(30)32-15-16-7-2-1-3-8-16/h1-5,7-10,19-20,25,31H,6,11-15H2,(H,24,30)(H,26,28)(H,27,29)/t19-,20-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353904
(CHEMBL1830508)Show SMILES ONC(=O)CN1C(=O)CC[C@H](NC(=O)[C@@H]2Cc3ccccc3CN2)C1=O |r| Show InChI InChI=1S/C17H20N4O5/c22-14(20-26)9-21-15(23)6-5-12(17(21)25)19-16(24)13-7-10-3-1-2-4-11(10)8-18-13/h1-4,12-13,18,26H,5-9H2,(H,19,24)(H,20,22)/t12-,13-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353907
(CHEMBL1830511)Show InChI InChI=1S/C12H15N3O3/c16-11(15-18)7-14-12(17)10-5-8-3-1-2-4-9(8)6-13-10/h1-4,10,13,18H,5-7H2,(H,14,17)(H,15,16)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353910
(CHEMBL1830649)Show SMILES CC(C)C[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C16H23N3O3/c1-10(2)7-14(16(21)19-22)18-15(20)13-8-11-5-3-4-6-12(11)9-17-13/h3-6,10,13-14,17,22H,7-9H2,1-2H3,(H,18,20)(H,19,21)/t13-,14-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM23971
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 2.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in human ES2 cells assessed as L-Leu-p-nitroanilide hydrolysis |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50353911
(CHEMBL1830651)Show SMILES ONC(=O)[C@@H](NC(=O)[C@@H]1Cc2ccccc2CN1)c1ccccc1 |r| Show InChI InChI=1S/C18H19N3O3/c22-17(15-10-13-8-4-5-9-14(13)11-19-15)20-16(18(23)21-24)12-6-2-1-3-7-12/h1-9,15-16,19,24H,10-11H2,(H,20,22)(H,21,23)/t15-,16-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in human ES2 cells assessed as L-Leu-p-nitroanilide hydrolysis |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353909
(CHEMBL1830648)Show SMILES CC(C)[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C15H21N3O3/c1-9(2)13(15(20)18-21)17-14(19)12-7-10-5-3-4-6-11(10)8-16-12/h3-6,9,12-13,16,21H,7-8H2,1-2H3,(H,17,19)(H,18,20)/t12-,13-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353905
(CHEMBL1830509)Show InChI InChI=1S/C13H17N3O3/c17-12(16-19)5-6-14-13(18)11-7-9-3-1-2-4-10(9)8-15-11/h1-4,11,15,19H,5-8H2,(H,14,18)(H,16,17)/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353916
(CHEMBL1830655)Show SMILES OC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C13H17N3O4/c17-7-11(13(19)16-20)15-12(18)10-5-8-3-1-2-4-9(8)6-14-10/h1-4,10-11,14,17,20H,5-7H2,(H,15,18)(H,16,19)/t10-,11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353922
(CHEMBL1830660)Show SMILES ONC(=O)[C@H](Cc1cc2ccccc2[nH]1)NC(=O)[C@@H]1Cc2ccccc2CN1 |r| Show InChI InChI=1S/C21H22N4O3/c26-20(18-10-13-5-1-2-7-15(13)12-22-18)24-19(21(27)25-28)11-16-9-14-6-3-4-8-17(14)23-16/h1-9,18-19,22-23,28H,10-12H2,(H,24,26)(H,25,27)/t18-,19-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353906
(CHEMBL1830510)Show InChI InChI=1S/C14H19N3O3/c18-13(17-20)6-3-7-15-14(19)12-8-10-4-1-2-5-11(10)9-16-12/h1-2,4-5,12,16,20H,3,6-9H2,(H,15,19)(H,17,18)/t12-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353917
(CHEMBL2369772)Show SMILES Cl.C[C@@H](O)[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C14H19N3O4/c1-8(18)12(14(20)17-21)16-13(19)11-6-9-4-2-3-5-10(9)7-15-11/h2-5,8,11-12,15,18,21H,6-7H2,1H3,(H,16,19)(H,17,20)/t8?,11-,12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353917
(CHEMBL2369772)Show SMILES Cl.C[C@@H](O)[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C14H19N3O4/c1-8(18)12(14(20)17-21)16-13(19)11-6-9-4-2-3-5-10(9)7-15-11/h2-5,8,11-12,15,18,21H,6-7H2,1H3,(H,16,19)(H,17,20)/t8?,11-,12-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353908
(CHEMBL1830512)Show SMILES C[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C13H17N3O3/c1-8(12(17)16-19)15-13(18)11-6-9-4-2-3-5-10(9)7-14-11/h2-5,8,11,14,19H,6-7H2,1H3,(H,15,18)(H,16,17)/t8-,11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353918
(CHEMBL1830657)Show SMILES ONC(=O)[C@@H]1CCCN1C(=O)[C@@H]1Cc2ccccc2CN1 |r| Show InChI InChI=1S/C15H19N3O3/c19-14(17-21)13-6-3-7-18(13)15(20)12-8-10-4-1-2-5-11(10)9-16-12/h1-2,4-5,12-13,16,21H,3,6-9H2,(H,17,19)/t12-,13-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.04E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353918
(CHEMBL1830657)Show SMILES ONC(=O)[C@@H]1CCCN1C(=O)[C@@H]1Cc2ccccc2CN1 |r| Show InChI InChI=1S/C15H19N3O3/c19-14(17-21)13-6-3-7-18(13)15(20)12-8-10-4-1-2-5-11(10)9-16-12/h1-2,4-5,12-13,16,21H,3,6-9H2,(H,17,19)/t12-,13-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.57E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM23971
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.63E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353915
(CHEMBL1830654)Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C15H21N3O3S/c1-22-7-6-12(15(20)18-21)17-14(19)13-8-10-4-2-3-5-11(10)9-16-13/h2-5,12-13,16,21H,6-9H2,1H3,(H,17,19)(H,18,20)/t12-,13-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.66E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353907
(CHEMBL1830511)Show InChI InChI=1S/C12H15N3O3/c16-11(15-18)7-14-12(17)10-5-8-3-1-2-4-9(8)6-13-10/h1-4,10,13,18H,5-7H2,(H,14,17)(H,15,16)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.49E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353906
(CHEMBL1830510)Show InChI InChI=1S/C14H19N3O3/c18-13(17-20)6-3-7-15-14(19)12-8-10-4-1-2-5-11(10)9-16-12/h1-2,4-5,12,16,20H,3,6-9H2,(H,15,19)(H,17,18)/t12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.52E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353916
(CHEMBL1830655)Show SMILES OC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C13H17N3O4/c17-7-11(13(19)16-20)15-12(18)10-5-8-3-1-2-4-9(8)6-14-10/h1-4,10-11,14,17,20H,5-7H2,(H,15,18)(H,16,19)/t10-,11-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.68E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353919
(CHEMBL1830658)Show SMILES ONC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H]1Cc2ccccc2CN1 |r| Show InChI InChI=1S/C15H19N3O4/c19-11-6-13(14(20)17-22)18(8-11)15(21)12-5-9-3-1-2-4-10(9)7-16-12/h1-4,11-13,16,19,22H,5-8H2,(H,17,20)/t11-,12+,13+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.76E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353909
(CHEMBL1830648)Show SMILES CC(C)[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C15H21N3O3/c1-9(2)13(15(20)18-21)17-14(19)12-7-10-5-3-4-6-11(10)8-16-12/h3-6,9,12-13,16,21H,7-8H2,1-2H3,(H,17,19)(H,18,20)/t12-,13-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.07E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353911
(CHEMBL1830651)Show SMILES ONC(=O)[C@@H](NC(=O)[C@@H]1Cc2ccccc2CN1)c1ccccc1 |r| Show InChI InChI=1S/C18H19N3O3/c22-17(15-10-13-8-4-5-9-14(13)11-19-15)20-16(18(23)21-24)12-6-2-1-3-7-12/h1-9,15-16,19,24H,10-11H2,(H,20,22)(H,21,23)/t15-,16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.93E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353925
(CHEMBL1830664)Show SMILES ONC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2ccccc2CN1 |r| Show InChI InChI=1S/C28H30N4O4/c33-26(23-17-21-13-7-8-14-22(21)18-29-23)30-24(15-19-9-3-1-4-10-19)27(34)31-25(28(35)32-36)16-20-11-5-2-6-12-20/h1-14,23-25,29,36H,15-18H2,(H,30,33)(H,31,34)(H,32,35)/t23-,24-,25-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.35E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353908
(CHEMBL1830512)Show SMILES C[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C13H17N3O3/c1-8(12(17)16-19)15-13(18)11-6-9-4-2-3-5-10(9)7-14-11/h2-5,8,11,14,19H,6-7H2,1H3,(H,15,18)(H,16,17)/t8-,11-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.63E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353920
(CHEMBL1830662)Show SMILES CC(C)C[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C25H32N4O4/c1-16(2)12-21(27-23(30)20-14-18-10-6-7-11-19(18)15-26-20)24(31)28-22(25(32)29-33)13-17-8-4-3-5-9-17/h3-11,16,20-22,26,33H,12-15H2,1-2H3,(H,27,30)(H,28,31)(H,29,32)/t20-,21-,22-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.65E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353923
(CHEMBL1830661)Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C22H34N4O4/c1-13(2)9-18(21(28)25-19(10-14(3)4)22(29)26-30)24-20(27)17-11-15-7-5-6-8-16(15)12-23-17/h5-8,13-14,17-19,23,30H,9-12H2,1-4H3,(H,24,27)(H,25,28)(H,26,29)/t17-,18-,19-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.81E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353905
(CHEMBL1830509)Show InChI InChI=1S/C13H17N3O3/c17-12(16-19)5-6-14-13(18)11-7-9-3-1-2-4-10(9)8-15-11/h1-4,11,15,19H,5-8H2,(H,14,18)(H,16,17)/t11-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.17E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353914
(CHEMBL1830653)Show SMILES ONC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1Cc2ccccc2CN1 |r| Show InChI InChI=1S/C19H21N3O4/c23-15-7-5-12(6-8-15)9-17(19(25)22-26)21-18(24)16-10-13-3-1-2-4-14(13)11-20-16/h1-8,16-17,20,23,26H,9-11H2,(H,21,24)(H,22,25)/t16-,17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50353924
(CHEMBL1830663)Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C25H32N4O4/c1-16(2)12-21(25(32)29-33)27-24(31)22(13-17-8-4-3-5-9-17)28-23(30)20-14-18-10-6-7-11-19(18)15-26-20/h3-11,16,20-22,26,33H,12-15H2,1-2H3,(H,27,31)(H,28,30)(H,29,32)/t20-,21-,22-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.55E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of pig kidney microsome aminopeptidase N using L-Leu-p-nitroanilide substrate |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353920
(CHEMBL1830662)Show SMILES CC(C)C[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C25H32N4O4/c1-16(2)12-21(27-23(30)20-14-18-10-6-7-11-19(18)15-26-20)24(31)28-22(25(32)29-33)13-17-8-4-3-5-9-17/h3-11,16,20-22,26,33H,12-15H2,1-2H3,(H,27,30)(H,28,31)(H,29,32)/t20-,21-,22-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.57E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353913
(CHEMBL2369771)Show SMILES Cl.CC[C@H](C)[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C16H23N3O3/c1-3-10(2)14(16(21)19-22)18-15(20)13-8-11-6-4-5-7-12(11)9-17-13/h4-7,10,13-14,17,22H,3,8-9H2,1-2H3,(H,18,20)(H,19,21)/t10?,13-,14-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.72E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353910
(CHEMBL1830649)Show SMILES CC(C)C[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NO |r| Show InChI InChI=1S/C16H23N3O3/c1-10(2)7-14(16(21)19-22)18-15(20)13-8-11-5-3-4-6-12(11)9-17-13/h3-6,10,13-14,17,22H,7-9H2,1-2H3,(H,18,20)(H,19,21)/t13-,14-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.36E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50353912
(CHEMBL1830652)Show SMILES ONC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2ccccc2CN1 |r| Show InChI InChI=1S/C19H21N3O3/c23-18(16-11-14-8-4-5-9-15(14)12-20-16)21-17(19(24)22-25)10-13-6-2-1-3-7-13/h1-9,16-17,20,25H,10-12H2,(H,21,23)(H,22,24)/t16-,17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shan Dong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 after 30 mins |
Bioorg Med Chem 19: 6015-25 (2011)
Article DOI: 10.1016/j.bmc.2011.08.041
BindingDB Entry DOI: 10.7270/Q2251JKK |
More data for this
Ligand-Target Pair | |
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