Affinity Data by PubMed id=21923187

PubMed code 21923187

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50355329 (CHEMBL1835336) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	3.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from recombinant GluA2 S1S2J soluble ligand binding domain				J Med Chem 54: 7289-98 (2011) Article DOI: 10.1021/jm200862h BindingDB Entry DOI: 10.7270/Q2QC03WT
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50355329 (CHEMBL1835336) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	6.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from recombinant rat GluA1 flop isoform receptor expressed in Sf9 insect cell membrane				J Med Chem 54: 7289-98 (2011) Article DOI: 10.1021/jm200862h BindingDB Entry DOI: 10.7270/Q2QC03WT
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 4 (Rattus norvegicus)	BDBM50355329 (CHEMBL1835336) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	2.04E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from recombinant rat GluA4 flop isoform receptor expressed in Sf9 insect cell membrane				J Med Chem 54: 7289-98 (2011) Article DOI: 10.1021/jm200862h BindingDB Entry DOI: 10.7270/Q2QC03WT
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 3 (RAT)	BDBM50355329 (CHEMBL1835336) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	2.27E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from recombinant rat GluA3 flop isoform receptor expressed in Sf9 insect cell membrane				J Med Chem 54: 7289-98 (2011) Article DOI: 10.1021/jm200862h BindingDB Entry DOI: 10.7270/Q2QC03WT
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 3 (RAT)	BDBM50355329 (CHEMBL1835336) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at recombinant rat GluA3 flip isoform receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced cu...				J Med Chem 54: 7289-98 (2011) Article DOI: 10.1021/jm200862h BindingDB Entry DOI: 10.7270/Q2QC03WT
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%