Found 95 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357308
(CHEMBL1916707)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1cccc(Cl)c1 Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-18-5-4-6-21(28)11-18)15-19-14-20(27(29,30)31)8-9-22(19)23-12-17(13-25(33)34)7-10-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357310
(CHEMBL1916710)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccc(F)cc1 Show InChI InChI=1S/C27H25F4NO5/c1-3-32(26(35)37-16-17-4-8-21(28)9-5-17)15-19-14-20(27(29,30)31)7-10-22(19)23-12-18(13-25(33)34)6-11-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357307
(CHEMBL1916706)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1Cl Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-18-6-4-5-7-23(18)28)15-19-14-20(27(29,30)31)9-10-21(19)22-12-17(13-25(33)34)8-11-24(22)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357311
(CHEMBL1916711)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1cc(F)cc(F)c1 Show InChI InChI=1S/C27H24F5NO5/c1-3-33(26(36)38-15-17-8-20(28)13-21(29)9-17)14-18-12-19(27(30,31)32)5-6-22(18)23-10-16(11-25(34)35)4-7-24(23)37-2/h4-10,12-13H,3,11,14-15H2,1-2H3,(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357289
(CHEMBL1916708)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccc(Cl)cc1 Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-17-4-8-21(28)9-5-17)15-19-14-20(27(29,30)31)7-10-22(19)23-12-18(13-25(33)34)6-11-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357309
(CHEMBL1916709)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C27H24Cl2F3NO5/c1-3-33(26(36)38-15-17-8-20(28)13-21(29)9-17)14-18-12-19(27(30,31)32)5-6-22(18)23-10-16(11-25(34)35)4-7-24(23)37-2/h4-10,12-13H,3,11,14-15H2,1-2H3,(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357302
(CHEMBL1916699)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN(C)C(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C26H24F3NO5/c1-30(25(33)35-16-17-6-4-3-5-7-17)15-19-14-20(26(27,28)29)9-10-21(19)22-12-18(13-24(31)32)8-11-23(22)34-2/h3-12,14H,13,15-16H2,1-2H3,(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357304
(CHEMBL1916702)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN(C1CCC1)C(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C29H28F3NO5/c1-37-26-13-10-20(15-27(34)35)14-25(26)24-12-11-22(29(30,31)32)16-21(24)17-33(23-8-5-9-23)28(36)38-18-19-6-3-2-4-7-19/h2-4,6-7,10-14,16,23H,5,8-9,15,17-18H2,1H3,(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357303
(CHEMBL1916701)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN(C1CC1)C(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C28H26F3NO5/c1-36-25-12-7-19(14-26(33)34)13-24(25)23-11-8-21(28(29,30)31)15-20(23)16-32(22-9-10-22)27(35)37-17-18-5-3-2-4-6-18/h2-8,11-13,15,22H,9-10,14,16-17H2,1H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357310
(CHEMBL1916710)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccc(F)cc1 Show InChI InChI=1S/C27H25F4NO5/c1-3-32(26(35)37-16-17-4-8-21(28)9-5-17)15-19-14-20(27(29,30)31)7-10-22(19)23-12-18(13-25(33)34)6-11-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357286
(CHEMBL1916700)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1 Show InChI InChI=1S/C27H26F3NO5/c1-3-31(26(34)36-17-18-7-5-4-6-8-18)16-20-15-21(27(28,29)30)10-11-22(20)23-13-19(14-25(32)33)9-12-24(23)35-2/h4-13,15H,3,14,16-17H2,1-2H3,(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357311
(CHEMBL1916711)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1cc(F)cc(F)c1 Show InChI InChI=1S/C27H24F5NO5/c1-3-33(26(36)38-15-17-8-20(28)13-21(29)9-17)14-18-12-19(27(30,31)32)5-6-22(18)23-10-16(11-25(34)35)4-7-24(23)37-2/h4-10,12-13H,3,11,14-15H2,1-2H3,(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357286
(CHEMBL1916700)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1 Show InChI InChI=1S/C27H26F3NO5/c1-3-31(26(34)36-17-18-7-5-4-6-8-18)16-20-15-21(27(28,29)30)10-11-22(20)23-13-19(14-25(32)33)9-12-24(23)35-2/h4-13,15H,3,14,16-17H2,1-2H3,(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357289
(CHEMBL1916708)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccc(Cl)cc1 Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-17-4-8-21(28)9-5-17)15-19-14-20(27(29,30)31)7-10-22(19)23-12-18(13-25(33)34)6-11-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357308
(CHEMBL1916707)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1cccc(Cl)c1 Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-18-5-4-6-21(28)11-18)15-19-14-20(27(29,30)31)8-9-22(19)23-12-17(13-25(33)34)7-10-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357289
(CHEMBL1916708)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccc(Cl)cc1 Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-17-4-8-21(28)9-5-17)15-19-14-20(27(29,30)31)7-10-22(19)23-12-18(13-25(33)34)6-11-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357307
(CHEMBL1916706)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1Cl Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-18-6-4-5-7-23(18)28)15-19-14-20(27(29,30)31)9-10-21(19)22-12-17(13-25(33)34)8-11-24(22)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357291
(CHEMBL1916704)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OC Show InChI InChI=1S/C21H22F3NO5/c1-4-25(20(28)30-3)12-14-11-15(21(22,23)24)6-7-16(14)17-9-13(10-19(26)27)5-8-18(17)29-2/h5-9,11H,4,10,12H2,1-3H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357290
(CHEMBL1916697)Show SMILES COC(=O)N(Cc1ccccc1)Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F Show InChI InChI=1S/C26H24F3NO5/c1-34-23-11-8-18(13-24(31)32)12-22(23)21-10-9-20(26(27,28)29)14-19(21)16-30(25(33)35-2)15-17-6-4-3-5-7-17/h3-12,14H,13,15-16H2,1-2H3,(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357286
(CHEMBL1916700)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1 Show InChI InChI=1S/C27H26F3NO5/c1-3-31(26(34)36-17-18-7-5-4-6-8-18)16-20-15-21(27(28,29)30)10-11-22(20)23-13-19(14-25(32)33)9-12-24(23)35-2/h4-13,15H,3,14,16-17H2,1-2H3,(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357310
(CHEMBL1916710)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccc(F)cc1 Show InChI InChI=1S/C27H25F4NO5/c1-3-32(26(35)37-16-17-4-8-21(28)9-5-17)15-19-14-20(27(29,30)31)7-10-22(19)23-12-18(13-25(33)34)6-11-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357302
(CHEMBL1916699)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN(C)C(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C26H24F3NO5/c1-30(25(33)35-16-17-6-4-3-5-7-17)15-19-14-20(26(27,28)29)9-10-21(19)22-12-18(13-24(31)32)8-11-23(22)34-2/h3-12,14H,13,15-16H2,1-2H3,(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357291
(CHEMBL1916704)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OC Show InChI InChI=1S/C21H22F3NO5/c1-4-25(20(28)30-3)12-14-11-15(21(22,23)24)6-7-16(14)17-9-13(10-19(26)27)5-8-18(17)29-2/h5-9,11H,4,10,12H2,1-3H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357303
(CHEMBL1916701)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN(C1CC1)C(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C28H26F3NO5/c1-36-25-12-7-19(14-26(33)34)13-24(25)23-11-8-21(28(29,30)31)15-20(23)16-32(22-9-10-22)27(35)37-17-18-5-3-2-4-6-18/h2-8,11-13,15,22H,9-10,14,16-17H2,1H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357308
(CHEMBL1916707)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1cccc(Cl)c1 Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-18-5-4-6-21(28)11-18)15-19-14-20(27(29,30)31)8-9-22(19)23-12-17(13-25(33)34)7-10-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357307
(CHEMBL1916706)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1Cl Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-18-6-4-5-7-23(18)28)15-19-14-20(27(29,30)31)9-10-21(19)22-12-17(13-25(33)34)8-11-24(22)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357311
(CHEMBL1916711)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1cc(F)cc(F)c1 Show InChI InChI=1S/C27H24F5NO5/c1-3-33(26(36)38-15-17-8-20(28)13-21(29)9-17)14-18-12-19(27(30,31)32)5-6-22(18)23-10-16(11-25(34)35)4-7-24(23)37-2/h4-10,12-13H,3,11,14-15H2,1-2H3,(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357305
(CHEMBL1916703)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN(C1CCCC1)C(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C30H30F3NO5/c1-38-27-14-11-21(16-28(35)36)15-26(27)25-13-12-23(30(31,32)33)17-22(25)18-34(24-9-5-6-10-24)29(37)39-19-20-7-3-2-4-8-20/h2-4,7-8,11-15,17,24H,5-6,9-10,16,18-19H2,1H3,(H,35,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357304
(CHEMBL1916702)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN(C1CCC1)C(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C29H28F3NO5/c1-37-26-13-10-20(15-27(34)35)14-25(26)24-12-11-22(29(30,31)32)16-21(24)17-33(23-8-5-9-23)28(36)38-18-19-6-3-2-4-7-19/h2-4,6-7,10-14,16,23H,5,8-9,15,17-18H2,1H3,(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357309
(CHEMBL1916709)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C27H24Cl2F3NO5/c1-3-33(26(36)38-15-17-8-20(28)13-21(29)9-17)14-18-12-19(27(30,31)32)5-6-22(18)23-10-16(11-25(34)35)4-7-24(23)37-2/h4-10,12-13H,3,11,14-15H2,1-2H3,(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357291
(CHEMBL1916704)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OC Show InChI InChI=1S/C21H22F3NO5/c1-4-25(20(28)30-3)12-14-11-15(21(22,23)24)6-7-16(14)17-9-13(10-19(26)27)5-8-18(17)29-2/h5-9,11H,4,10,12H2,1-3H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357302
(CHEMBL1916699)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN(C)C(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C26H24F3NO5/c1-30(25(33)35-16-17-6-4-3-5-7-17)15-19-14-20(26(27,28)29)9-10-21(19)22-12-18(13-24(31)32)8-11-23(22)34-2/h3-12,14H,13,15-16H2,1-2H3,(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357303
(CHEMBL1916701)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN(C1CC1)C(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C28H26F3NO5/c1-36-25-12-7-19(14-26(33)34)13-24(25)23-11-8-21(28(29,30)31)15-20(23)16-32(22-9-10-22)27(35)37-17-18-5-3-2-4-6-18/h2-8,11-13,15,22H,9-10,14,16-17H2,1H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357304
(CHEMBL1916702)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN(C1CCC1)C(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C29H28F3NO5/c1-37-26-13-10-20(15-27(34)35)14-25(26)24-12-11-22(29(30,31)32)16-21(24)17-33(23-8-5-9-23)28(36)38-18-19-6-3-2-4-7-19/h2-4,6-7,10-14,16,23H,5,8-9,15,17-18H2,1H3,(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357290
(CHEMBL1916697)Show SMILES COC(=O)N(Cc1ccccc1)Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F Show InChI InChI=1S/C26H24F3NO5/c1-34-23-11-8-18(13-24(31)32)12-22(23)21-10-9-20(26(27,28)29)14-19(21)16-30(25(33)35-2)15-17-6-4-3-5-7-17/h3-12,14H,13,15-16H2,1-2H3,(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357300
(CHEMBL1916696)Show SMILES COC(=O)N(CCc1ccccc1)Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F Show InChI InChI=1S/C27H26F3NO5/c1-35-24-11-8-19(15-25(32)33)14-23(24)22-10-9-21(27(28,29)30)16-20(22)17-31(26(34)36-2)13-12-18-6-4-3-5-7-18/h3-11,14,16H,12-13,15,17H2,1-2H3,(H,32,33) | PDB
Reactome pathway
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PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357309
(CHEMBL1916709)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C27H24Cl2F3NO5/c1-3-33(26(36)38-15-17-8-20(28)13-21(29)9-17)14-18-12-19(27(30,31)32)5-6-22(18)23-10-16(11-25(34)35)4-7-24(23)37-2/h4-10,12-13H,3,11,14-15H2,1-2H3,(H,34,35) | PDB
Reactome pathway
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UniChem
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| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357290
(CHEMBL1916697)Show SMILES COC(=O)N(Cc1ccccc1)Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F Show InChI InChI=1S/C26H24F3NO5/c1-34-23-11-8-18(13-24(31)32)12-22(23)21-10-9-20(26(27,28)29)14-19(21)16-30(25(33)35-2)15-17-6-4-3-5-7-17/h3-12,14H,13,15-16H2,1-2H3,(H,31,32) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Similars
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PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357300
(CHEMBL1916696)Show SMILES COC(=O)N(CCc1ccccc1)Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F Show InChI InChI=1S/C27H26F3NO5/c1-35-24-11-8-19(15-25(32)33)14-23(24)22-10-9-21(27(28,29)30)16-20(22)17-31(26(34)36-2)13-12-18-6-4-3-5-7-18/h3-11,14,16H,12-13,15,17H2,1-2H3,(H,32,33) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Similars
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PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357301
(CHEMBL1916698)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CNC(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C25H22F3NO5/c1-33-22-10-7-17(12-23(30)31)11-21(22)20-9-8-19(25(26,27)28)13-18(20)14-29-24(32)34-15-16-5-3-2-4-6-16/h2-11,13H,12,14-15H2,1H3,(H,29,32)(H,30,31) | PDB
Reactome pathway
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PC sid
UniChem
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PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357305
(CHEMBL1916703)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN(C1CCCC1)C(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C30H30F3NO5/c1-38-27-14-11-21(16-28(35)36)15-26(27)25-13-12-23(30(31,32)33)17-22(25)18-34(24-9-5-6-10-24)29(37)39-19-20-7-3-2-4-8-20/h2-4,7-8,11-15,17,24H,5-6,9-10,16,18-19H2,1H3,(H,35,36) | PDB
Reactome pathway
KEGG
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UniChem
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PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357305
(CHEMBL1916703)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN(C1CCCC1)C(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C30H30F3NO5/c1-38-27-14-11-21(16-28(35)36)15-26(27)25-13-12-23(30(31,32)33)17-22(25)18-34(24-9-5-6-10-24)29(37)39-19-20-7-3-2-4-8-20/h2-4,7-8,11-15,17,24H,5-6,9-10,16,18-19H2,1H3,(H,35,36) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357300
(CHEMBL1916696)Show SMILES COC(=O)N(CCc1ccccc1)Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F Show InChI InChI=1S/C27H26F3NO5/c1-35-24-11-8-19(15-25(32)33)14-23(24)22-10-9-21(27(28,29)30)16-20(22)17-31(26(34)36-2)13-12-18-6-4-3-5-7-18/h3-11,14,16H,12-13,15,17H2,1-2H3,(H,32,33) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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PubMed
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357287
(CHEMBL1916686)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN1[C@@H](C)[C@H](OC1=O)c1ccccc1)C(F)(F)F |r| Show InChI InChI=1S/C27H24F3NO5/c1-16-25(18-6-4-3-5-7-18)36-26(34)31(16)15-19-14-20(27(28,29)30)9-10-21(19)22-12-17(13-24(32)33)8-11-23(22)35-2/h3-12,14,16,25H,13,15H2,1-2H3,(H,32,33)/t16-,25-/m0/s1 | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
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PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357301
(CHEMBL1916698)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CNC(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C25H22F3NO5/c1-33-22-10-7-17(12-23(30)31)11-21(22)20-9-8-19(25(26,27)28)13-18(20)14-29-24(32)34-15-16-5-3-2-4-6-16/h2-11,13H,12,14-15H2,1H3,(H,29,32)(H,30,31) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 238 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357288
(CHEMBL1916687)Show SMILES C[C@H]1[C@H](OC(=O)N1Cc1cc(ccc1-c1cccc(CC(O)=O)c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C26H22F3NO4/c1-16-24(18-7-3-2-4-8-18)34-25(33)30(16)15-20-14-21(26(27,28)29)10-11-22(20)19-9-5-6-17(12-19)13-23(31)32/h2-12,14,16,24H,13,15H2,1H3,(H,31,32)/t16-,24-/m0/s1 | PDB
Reactome pathway
KEGG
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DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357296
(CHEMBL1916692)Show SMILES C[C@H]1[C@H](OC(=O)N1Cc1cc(F)ccc1-c1ccc(CC(O)=O)cc1)c1ccccc1 |r| Show InChI InChI=1S/C25H22FNO4/c1-16-24(19-5-3-2-4-6-19)31-25(30)27(16)15-20-14-21(26)11-12-22(20)18-9-7-17(8-10-18)13-23(28)29/h2-12,14,16,24H,13,15H2,1H3,(H,28,29)/t16-,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357297
(CHEMBL1916693)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(F)cc1CN1[C@@H](C)[C@H](OC1=O)c1ccccc1 |r| Show InChI InChI=1S/C26H24FNO5/c1-16-25(18-6-4-3-5-7-18)33-26(31)28(16)15-19-14-20(27)9-10-21(19)22-12-17(13-24(29)30)8-11-23(22)32-2/h3-12,14,16,25H,13,15H2,1-2H3,(H,29,30)/t16-,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357301
(CHEMBL1916698)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CNC(=O)OCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C25H22F3NO5/c1-33-22-10-7-17(12-23(30)31)11-21(22)20-9-8-19(25(26,27)28)13-18(20)14-29-24(32)34-15-16-5-3-2-4-6-16/h2-11,13H,12,14-15H2,1H3,(H,29,32)(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 709 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357298
(CHEMBL1916694)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccccc1CN1[C@@H](C)[C@H](OC1=O)c1ccccc1 |r| Show InChI InChI=1S/C26H25NO5/c1-17-25(19-8-4-3-5-9-19)32-26(30)27(17)16-20-10-6-7-11-21(20)22-14-18(15-24(28)29)12-13-23(22)31-2/h3-14,17,25H,15-16H2,1-2H3,(H,28,29)/t17-,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357299
(CHEMBL1916695)Show SMILES COc1ccc(c(CN2[C@@H](C)[C@H](OC2=O)c2ccccc2)c1)-c1cc(CC(O)=O)ccc1OC |r| Show InChI InChI=1S/C27H27NO6/c1-17-26(19-7-5-4-6-8-19)34-27(31)28(17)16-20-15-21(32-2)10-11-22(20)23-13-18(14-25(29)30)9-12-24(23)33-3/h4-13,15,17,26H,14,16H2,1-3H3,(H,29,30)/t17-,26-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357297
(CHEMBL1916693)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(F)cc1CN1[C@@H](C)[C@H](OC1=O)c1ccccc1 |r| Show InChI InChI=1S/C26H24FNO5/c1-16-25(18-6-4-3-5-7-18)33-26(31)28(16)15-19-14-20(27)9-10-21(19)22-12-17(13-24(29)30)8-11-23(22)32-2/h3-12,14,16,25H,13,15H2,1-2H3,(H,29,30)/t16-,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357296
(CHEMBL1916692)Show SMILES C[C@H]1[C@H](OC(=O)N1Cc1cc(F)ccc1-c1ccc(CC(O)=O)cc1)c1ccccc1 |r| Show InChI InChI=1S/C25H22FNO4/c1-16-24(19-5-3-2-4-6-19)31-25(30)27(16)15-20-14-21(26)11-12-22(20)18-9-7-17(8-10-18)13-23(28)29/h2-12,14,16,24H,13,15H2,1H3,(H,28,29)/t16-,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357298
(CHEMBL1916694)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccccc1CN1[C@@H](C)[C@H](OC1=O)c1ccccc1 |r| Show InChI InChI=1S/C26H25NO5/c1-17-25(19-8-4-3-5-9-19)32-26(30)27(17)16-20-10-6-7-11-21(20)22-14-18(15-24(28)29)12-13-23(22)31-2/h3-14,17,25H,15-16H2,1-2H3,(H,28,29)/t17-,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357288
(CHEMBL1916687)Show SMILES C[C@H]1[C@H](OC(=O)N1Cc1cc(ccc1-c1cccc(CC(O)=O)c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C26H22F3NO4/c1-16-24(18-7-3-2-4-8-18)34-25(33)30(16)15-20-14-21(26(27,28)29)10-11-22(20)19-9-5-6-17(12-19)13-23(31)32/h2-12,14,16,24H,13,15H2,1H3,(H,31,32)/t16-,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357306
(CHEMBL1916705)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CNCCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C25H24F3NO3/c1-32-23-10-7-18(14-24(30)31)13-22(23)21-9-8-20(25(26,27)28)15-19(21)16-29-12-11-17-5-3-2-4-6-17/h2-10,13,15,29H,11-12,14,16H2,1H3,(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50357289
(CHEMBL1916708)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccc(Cl)cc1 Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-17-4-8-21(28)9-5-17)15-19-14-20(27(29,30)31)7-10-22(19)23-12-18(13-25(33)34)6-11-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human DP1 receptor expressed in human platelet membranes |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50357286
(CHEMBL1916700)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1 Show InChI InChI=1S/C27H26F3NO5/c1-3-31(26(34)36-17-18-7-5-4-6-8-18)16-20-15-21(27(28,29)30)10-11-22(20)23-13-19(14-25(32)33)9-12-24(23)35-2/h4-13,15H,3,14,16-17H2,1-2H3,(H,32,33) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human DP1 receptor expressed in human platelet membranes |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357287
(CHEMBL1916686)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN1[C@@H](C)[C@H](OC1=O)c1ccccc1)C(F)(F)F |r| Show InChI InChI=1S/C27H24F3NO5/c1-16-25(18-6-4-3-5-7-18)36-26(34)31(16)15-19-14-20(27(28,29)30)9-10-21(19)22-12-17(13-24(32)33)8-11-23(22)35-2/h3-12,14,16,25H,13,15H2,1-2H3,(H,32,33)/t16-,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357299
(CHEMBL1916695)Show SMILES COc1ccc(c(CN2[C@@H](C)[C@H](OC2=O)c2ccccc2)c1)-c1cc(CC(O)=O)ccc1OC |r| Show InChI InChI=1S/C27H27NO6/c1-17-26(19-7-5-4-6-8-19)34-27(31)28(17)16-20-15-21(32-2)10-11-22(20)23-13-18(14-25(29)30)9-12-24(23)33-3/h4-13,15,17,26H,14,16H2,1-3H3,(H,29,30)/t17-,26-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357293
(CHEMBL1916689)Show SMILES C[C@H]1[C@H](OC(=O)N1Cc1cc(ccc1-c1cccc(CCC(O)=O)c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C27H24F3NO4/c1-17-25(19-7-3-2-4-8-19)35-26(34)31(17)16-21-15-22(27(28,29)30)11-12-23(21)20-9-5-6-18(14-20)10-13-24(32)33/h2-9,11-12,14-15,17,25H,10,13,16H2,1H3,(H,32,33)/t17-,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357306
(CHEMBL1916705)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CNCCc1ccccc1)C(F)(F)F Show InChI InChI=1S/C25H24F3NO3/c1-32-23-10-7-18(14-24(30)31)13-22(23)21-9-8-20(25(26,27)28)15-19(21)16-29-12-11-17-5-3-2-4-6-17/h2-10,13,15,29H,11-12,14,16H2,1H3,(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357295
(CHEMBL1916691)Show SMILES C[C@H]1[C@H](OC(=O)N1Cc1cc(ccc1-c1ccccc1CCC(O)=O)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C27H24F3NO4/c1-17-25(19-8-3-2-4-9-19)35-26(34)31(17)16-20-15-21(27(28,29)30)12-13-23(20)22-10-6-5-7-18(22)11-14-24(32)33/h2-10,12-13,15,17,25H,11,14,16H2,1H3,(H,32,33)/t17-,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50357289
(CHEMBL1916708)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccc(Cl)cc1 Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-17-4-8-21(28)9-5-17)15-19-14-20(27(29,30)31)7-10-22(19)23-12-18(13-25(33)34)6-11-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-SQ-29,548 from human TP receptor expressed in human platelet membranes |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50357290
(CHEMBL1916697)Show SMILES COC(=O)N(Cc1ccccc1)Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F Show InChI InChI=1S/C26H24F3NO5/c1-34-23-11-8-18(13-24(31)32)12-22(23)21-10-9-20(26(27,28)29)14-19(21)16-30(25(33)35-2)15-17-6-4-3-5-7-17/h3-12,14H,13,15-16H2,1-2H3,(H,31,32) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human DP1 receptor expressed in human platelet membranes |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50357289
(CHEMBL1916708)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccc(Cl)cc1 Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-17-4-8-21(28)9-5-17)15-19-14-20(27(29,30)31)7-10-22(19)23-12-18(13-25(33)34)6-11-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP2C9 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50357286
(CHEMBL1916700)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1 Show InChI InChI=1S/C27H26F3NO5/c1-3-31(26(34)36-17-18-7-5-4-6-8-18)16-20-15-21(27(28,29)30)10-11-22(20)23-13-19(14-25(32)33)9-12-24(23)35-2/h4-13,15H,3,14,16-17H2,1-2H3,(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP2C9 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50357286
(CHEMBL1916700)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1 Show InChI InChI=1S/C27H26F3NO5/c1-3-31(26(34)36-17-18-7-5-4-6-8-18)16-20-15-21(27(28,29)30)10-11-22(20)23-13-19(14-25(32)33)9-12-24(23)35-2/h4-13,15H,3,14,16-17H2,1-2H3,(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP3A4 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50357289
(CHEMBL1916708)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccc(Cl)cc1 Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-17-4-8-21(28)9-5-17)15-19-14-20(27(29,30)31)7-10-22(19)23-12-18(13-25(33)34)6-11-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP3A4 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50357286
(CHEMBL1916700)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1 Show InChI InChI=1S/C27H26F3NO5/c1-3-31(26(34)36-17-18-7-5-4-6-8-18)16-20-15-21(27(28,29)30)10-11-22(20)23-13-19(14-25(32)33)9-12-24(23)35-2/h4-13,15H,3,14,16-17H2,1-2H3,(H,32,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-SQ-29,548 from human TP receptor expressed in human platelet membranes |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357292
(CHEMBL1916688)Show SMILES C[C@H]1[C@H](OC(=O)N1Cc1cc(ccc1-c1cccc(c1)C(O)=O)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C25H20F3NO4/c1-15-22(16-6-3-2-4-7-16)33-24(32)29(15)14-19-13-20(25(26,27)28)10-11-21(19)17-8-5-9-18(12-17)23(30)31/h2-13,15,22H,14H2,1H3,(H,30,31)/t15-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50357286
(CHEMBL1916700)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1 Show InChI InChI=1S/C27H26F3NO5/c1-3-31(26(34)36-17-18-7-5-4-6-8-18)16-20-15-21(27(28,29)30)10-11-22(20)23-13-19(14-25(32)33)9-12-24(23)35-2/h4-13,15H,3,14,16-17H2,1-2H3,(H,32,33) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP2D6 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50357286
(CHEMBL1916700)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1 Show InChI InChI=1S/C27H26F3NO5/c1-3-31(26(34)36-17-18-7-5-4-6-8-18)16-20-15-21(27(28,29)30)10-11-22(20)23-13-19(14-25(32)33)9-12-24(23)35-2/h4-13,15H,3,14,16-17H2,1-2H3,(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human ERG by patch clamp assay |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50357290
(CHEMBL1916697)Show SMILES COC(=O)N(Cc1ccccc1)Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F Show InChI InChI=1S/C26H24F3NO5/c1-34-23-11-8-18(13-24(31)32)12-22(23)21-10-9-20(26(27,28)29)14-19(21)16-30(25(33)35-2)15-17-6-4-3-5-7-17/h3-12,14H,13,15-16H2,1-2H3,(H,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP3A4 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50357291
(CHEMBL1916704)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OC Show InChI InChI=1S/C21H22F3NO5/c1-4-25(20(28)30-3)12-14-11-15(21(22,23)24)6-7-16(14)17-9-13(10-19(26)27)5-8-18(17)29-2/h5-9,11H,4,10,12H2,1-3H3,(H,26,27) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP2D6 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50357287
(CHEMBL1916686)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN1[C@@H](C)[C@H](OC1=O)c1ccccc1)C(F)(F)F |r| Show InChI InChI=1S/C27H24F3NO5/c1-16-25(18-6-4-3-5-7-18)36-26(34)31(16)15-19-14-20(27(28,29)30)9-10-21(19)22-12-17(13-24(32)33)8-11-23(22)35-2/h3-12,14,16,25H,13,15H2,1-2H3,(H,32,33)/t16-,25-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP2D6 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50357289
(CHEMBL1916708)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccc(Cl)cc1 Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-17-4-8-21(28)9-5-17)15-19-14-20(27(29,30)31)7-10-22(19)23-12-18(13-25(33)34)6-11-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP2D6 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50357290
(CHEMBL1916697)Show SMILES COC(=O)N(Cc1ccccc1)Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F Show InChI InChI=1S/C26H24F3NO5/c1-34-23-11-8-18(13-24(31)32)12-22(23)21-10-9-20(26(27,28)29)14-19(21)16-30(25(33)35-2)15-17-6-4-3-5-7-17/h3-12,14H,13,15-16H2,1-2H3,(H,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP2C9 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50357290
(CHEMBL1916697)Show SMILES COC(=O)N(Cc1ccccc1)Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F Show InChI InChI=1S/C26H24F3NO5/c1-34-23-11-8-18(13-24(31)32)12-22(23)21-10-9-20(26(27,28)29)14-19(21)16-30(25(33)35-2)15-17-6-4-3-5-7-17/h3-12,14H,13,15-16H2,1-2H3,(H,31,32) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP2D6 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50357287
(CHEMBL1916686)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN1[C@@H](C)[C@H](OC1=O)c1ccccc1)C(F)(F)F |r| Show InChI InChI=1S/C27H24F3NO5/c1-16-25(18-6-4-3-5-7-18)36-26(34)31(16)15-19-14-20(27(28,29)30)9-10-21(19)22-12-17(13-24(32)33)8-11-23(22)35-2/h3-12,14,16,25H,13,15H2,1-2H3,(H,32,33)/t16-,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP3A4 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50357291
(CHEMBL1916704)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OC Show InChI InChI=1S/C21H22F3NO5/c1-4-25(20(28)30-3)12-14-11-15(21(22,23)24)6-7-16(14)17-9-13(10-19(26)27)5-8-18(17)29-2/h5-9,11H,4,10,12H2,1-3H3,(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP2C9 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50357287
(CHEMBL1916686)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN1[C@@H](C)[C@H](OC1=O)c1ccccc1)C(F)(F)F |r| Show InChI InChI=1S/C27H24F3NO5/c1-16-25(18-6-4-3-5-7-18)36-26(34)31(16)15-19-14-20(27(28,29)30)9-10-21(19)22-12-17(13-24(32)33)8-11-23(22)35-2/h3-12,14,16,25H,13,15H2,1-2H3,(H,32,33)/t16-,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP2C9 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50357291
(CHEMBL1916704)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OC Show InChI InChI=1S/C21H22F3NO5/c1-4-25(20(28)30-3)12-14-11-15(21(22,23)24)6-7-16(14)17-9-13(10-19(26)27)5-8-18(17)29-2/h5-9,11H,4,10,12H2,1-3H3,(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human CYP3A4 |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50357287
(CHEMBL1916686)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN1[C@@H](C)[C@H](OC1=O)c1ccccc1)C(F)(F)F |r| Show InChI InChI=1S/C27H24F3NO5/c1-16-25(18-6-4-3-5-7-18)36-26(34)31(16)15-19-14-20(27(28,29)30)9-10-21(19)22-12-17(13-24(32)33)8-11-23(22)35-2/h3-12,14,16,25H,13,15H2,1-2H3,(H,32,33)/t16-,25-/m0/s1 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human DP1 receptor expressed in human platelet membranes |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50357289
(CHEMBL1916708)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccc(Cl)cc1 Show InChI InChI=1S/C27H25ClF3NO5/c1-3-32(26(35)37-16-17-4-8-21(28)9-5-17)15-19-14-20(27(29,30)31)7-10-22(19)23-12-18(13-25(33)34)6-11-24(23)36-2/h4-12,14H,3,13,15-16H2,1-2H3,(H,33,34) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-iloprost from human prostanoid IP receptor expressed in human 293T cells membranes |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50357291
(CHEMBL1916704)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OC Show InChI InChI=1S/C21H22F3NO5/c1-4-25(20(28)30-3)12-14-11-15(21(22,23)24)6-7-16(14)17-9-13(10-19(26)27)5-8-18(17)29-2/h5-9,11H,4,10,12H2,1-3H3,(H,26,27) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human DP1 receptor expressed in human platelet membranes |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357295
(CHEMBL1916691)Show SMILES C[C@H]1[C@H](OC(=O)N1Cc1cc(ccc1-c1ccccc1CCC(O)=O)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C27H24F3NO4/c1-17-25(19-8-3-2-4-9-19)35-26(34)31(17)16-20-15-21(27(28,29)30)12-13-23(20)22-10-6-5-7-18(22)11-14-24(32)33/h2-10,12-13,15,17,25H,11,14,16H2,1H3,(H,32,33)/t17-,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357294
(CHEMBL1916690)Show SMILES C[C@H]1[C@H](OC(=O)N1Cc1cc(ccc1-c1ccccc1CC(O)=O)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C26H22F3NO4/c1-16-24(17-7-3-2-4-8-17)34-25(33)30(16)15-19-13-20(26(27,28)29)11-12-22(19)21-10-6-5-9-18(21)14-23(31)32/h2-13,16,24H,14-15H2,1H3,(H,31,32)/t16-,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50357286
(CHEMBL1916700)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OCc1ccccc1 Show InChI InChI=1S/C27H26F3NO5/c1-3-31(26(34)36-17-18-7-5-4-6-8-18)16-20-15-21(27(28,29)30)10-11-22(20)23-13-19(14-25(32)33)9-12-24(23)35-2/h4-13,15H,3,14,16-17H2,1-2H3,(H,32,33) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.62E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-iloprost from human prostanoid IP receptor expressed in human 293T cells membranes |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357294
(CHEMBL1916690)Show SMILES C[C@H]1[C@H](OC(=O)N1Cc1cc(ccc1-c1ccccc1CC(O)=O)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C26H22F3NO4/c1-16-24(17-7-3-2-4-8-17)34-25(33)30(16)15-19-13-20(26(27,28)29)11-12-22(19)21-10-6-5-9-18(21)14-23(31)32/h2-13,16,24H,14-15H2,1H3,(H,31,32)/t16-,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50357290
(CHEMBL1916697)Show SMILES COC(=O)N(Cc1ccccc1)Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F Show InChI InChI=1S/C26H24F3NO5/c1-34-23-11-8-18(13-24(31)32)12-22(23)21-10-9-20(26(27,28)29)14-19(21)16-30(25(33)35-2)15-17-6-4-3-5-7-17/h3-12,14H,13,15-16H2,1-2H3,(H,31,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-SQ-29,548 from human TP receptor expressed in human platelet membranes |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50357287
(CHEMBL1916686)Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(cc1CN1[C@@H](C)[C@H](OC1=O)c1ccccc1)C(F)(F)F |r| Show InChI InChI=1S/C27H24F3NO5/c1-16-25(18-6-4-3-5-7-18)36-26(34)31(16)15-19-14-20(27(28,29)30)9-10-21(19)22-12-17(13-24(32)33)8-11-23(22)35-2/h3-12,14,16,25H,13,15H2,1-2H3,(H,32,33)/t16-,25-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-SQ-29,548 from human TP receptor expressed in human platelet membranes |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50357291
(CHEMBL1916704)Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F)C(=O)OC Show InChI InChI=1S/C21H22F3NO5/c1-4-25(20(28)30-3)12-14-11-15(21(22,23)24)6-7-16(14)17-9-13(10-19(26)27)5-8-18(17)29-2/h5-9,11H,4,10,12H2,1-3H3,(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.74E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-SQ-29,548 from human TP receptor expressed in human platelet membranes |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357293
(CHEMBL1916689)Show SMILES C[C@H]1[C@H](OC(=O)N1Cc1cc(ccc1-c1cccc(CCC(O)=O)c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C27H24F3NO4/c1-17-25(19-7-3-2-4-8-19)35-26(34)31(17)16-21-15-22(27(28,29)30)11-12-23(21)20-9-5-6-18(14-20)10-13-24(32)33/h2-9,11-12,14-15,17,25H,10,13,16H2,1H3,(H,32,33)/t17-,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50357292
(CHEMBL1916688)Show SMILES C[C@H]1[C@H](OC(=O)N1Cc1cc(ccc1-c1cccc(c1)C(O)=O)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C25H20F3NO4/c1-15-22(16-6-3-2-4-7-16)33-24(32)29(15)14-19-13-20(25(26,27)28)10-11-21(19)17-8-5-9-18(12-17)23(30)31/h2-13,15,22H,14H2,1H3,(H,30,31)/t15-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amira Pharmaceuticals
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma... |
Bioorg Med Chem Lett 21: 6608-12 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.024
BindingDB Entry DOI: 10.7270/Q2513ZM9 |
More data for this
Ligand-Target Pair | |
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