BindingDB logo
myBDB logout

PubMed code 21967807

Compile data set for download or QSAR
Found 36 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357453
PNG
(CHEMBL1917719)
Show SMILES CC(CCN1CCCCC1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C21H27N/c1-18(14-17-22-15-6-3-7-16-22)19-10-12-21(13-11-19)20-8-4-2-5-9-20/h2,4-5,8-13,18H,3,6-7,14-17H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 0.700n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357441
PNG
(CHEMBL1917705)
Show SMILES C\C(=C/CN1CCCCC1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C21H25N/c1-18(14-17-22-15-6-3-7-16-22)19-10-12-21(13-11-19)20-8-4-2-5-9-20/h2,4-5,8-14H,3,6-7,15-17H2,1H3/b18-14+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 0.860n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357440
PNG
(CHEMBL1917704)
Show SMILES C\C(=C/CN1CCCCC1)c1ccc2ccccc2c1
Show InChI InChI=1S/C19H23N/c1-16(11-14-20-12-5-2-6-13-20)18-10-9-17-7-3-4-8-19(17)15-18/h3-4,7-11,15H,2,5-6,12-14H2,1H3/b16-11+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 0.970n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357430
PNG
(CHEMBL1917711)
Show SMILES C\C(=C/CN1CCC(Cc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C22H27N/c1-19(22-10-6-3-7-11-22)12-15-23-16-13-21(14-17-23)18-20-8-4-2-5-9-20/h2-12,21H,13-18H2,1H3/b19-12+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 1.07n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50198061
PNG
((E)-N,N-dimethyl-3-(biphen-4-yl)but-2-en-1-ylamine...)
Show SMILES CN(C)C\C=C(/C)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C18H21N/c1-15(13-14-19(2)3)16-9-11-18(12-10-16)17-7-5-4-6-8-17/h4-13H,14H2,1-3H3/b15-13+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 1.40n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357431
PNG
(CHEMBL1917712)
Show SMILES COc1ccc(cc1)C(\C)=C\CN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H29NO/c1-19(22-8-10-23(25-2)11-9-22)12-15-24-16-13-21(14-17-24)18-20-6-4-3-5-7-20/h3-12,21H,13-18H2,1-2H3/b19-12+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 4.14n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357429
PNG
(CHEMBL1917702)
Show SMILES COc1ccc(cc1)C(\C)=C\CN(C)Cc1ccccc1
Show InChI InChI=1S/C19H23NO/c1-16(18-9-11-19(21-3)12-10-18)13-14-20(2)15-17-7-5-4-6-8-17/h4-13H,14-15H2,1-3H3/b16-13+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 5.25n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50198065
PNG
(4(E)-N-Benzyl-3-(biphenyl-4-yl)-N-methylbut-2-en-1...)
Show SMILES CN(C\C=C(/C)c1ccc(cc1)-c1ccccc1)Cc1ccccc1
Show InChI InChI=1S/C24H25N/c1-20(17-18-25(2)19-21-9-5-3-6-10-21)22-13-15-24(16-14-22)23-11-7-4-8-12-23/h3-17H,18-19H2,1-2H3/b20-17+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 6.32n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357446
PNG
(CHEMBL1917710)
Show SMILES C\C(=C/CN1CCC(Cc2ccccc2)CC1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C28H31N/c1-23(26-12-14-28(15-13-26)27-10-6-3-7-11-27)16-19-29-20-17-25(18-21-29)22-24-8-4-2-5-9-24/h2-16,25H,17-22H2,1H3/b23-16+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 7.02n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357447
PNG
(CHEMBL1917713)
Show SMILES COc1cccc(c1)C(\C)=C\CN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H29NO/c1-19(22-9-6-10-23(18-22)25-2)11-14-24-15-12-21(13-16-24)17-20-7-4-3-5-8-20/h3-11,18,21H,12-17H2,1-2H3/b19-11+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 7.70n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50198058
PNG
((E)-N-benzyl-N-methyl-3-(naphthalen-2-yl)but-2-en-...)
Show SMILES CN(C\C=C(/C)c1ccc2ccccc2c1)Cc1ccccc1
Show InChI InChI=1S/C22H23N/c1-18(14-15-23(2)17-19-8-4-3-5-9-19)21-13-12-20-10-6-7-11-22(20)16-21/h3-14,16H,15,17H2,1-2H3/b18-14+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 7.88n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357448
PNG
(CHEMBL1917714)
Show SMILES C\C(=C/CN1CCOCC1)c1ccc2ccccc2c1
Show InChI InChI=1S/C18H21NO/c1-15(8-9-19-10-12-20-13-11-19)17-7-6-16-4-2-3-5-18(16)14-17/h2-8,14H,9-13H2,1H3/b15-8+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 9.60n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357432
PNG
(CHEMBL1917703)
Show SMILES COc1cccc(c1)C(\C)=C\CN(C)Cc1ccccc1
Show InChI InChI=1S/C19H23NO/c1-16(18-10-7-11-19(14-18)21-3)12-13-20(2)15-17-8-5-4-6-9-17/h4-12,14H,13,15H2,1-3H3/b16-12+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 10n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357449
PNG
(CHEMBL1917715)
Show SMILES C\C(=C/CN1CCOCC1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C20H23NO/c1-17(11-12-21-13-15-22-16-14-21)18-7-9-20(10-8-18)19-5-3-2-4-6-19/h2-11H,12-16H2,1H3/b17-11+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 11.6n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357443
PNG
(CHEMBL1917707)
Show SMILES COc1ccc(cc1)C(\C)=C\CN1CCCCC1
Show InChI InChI=1S/C16H23NO/c1-14(10-13-17-11-4-3-5-12-17)15-6-8-16(18-2)9-7-15/h6-10H,3-5,11-13H2,1-2H3/b14-10+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 14n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50198068
PNG
((E)-N,N-dimethyl-3-(naphthalen-2-yl)but-2-en-1-ami...)
Show SMILES CN(C)C\C=C(/C)c1ccc2ccccc2c1
Show InChI InChI=1S/C16H19N/c1-13(10-11-17(2)3)15-9-8-14-6-4-5-7-16(14)12-15/h4-10,12H,11H2,1-3H3/b13-10+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 19.8n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357445
PNG
(CHEMBL1917709)
Show SMILES C\C(=C/CN1CCC(Cc2ccccc2)CC1)c1ccc2ccccc2c1
Show InChI InChI=1S/C26H29N/c1-21(25-12-11-24-9-5-6-10-26(24)20-25)13-16-27-17-14-23(15-18-27)19-22-7-3-2-4-8-22/h2-13,20,23H,14-19H2,1H3/b21-13+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 23n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357444
PNG
(CHEMBL1917708)
Show SMILES COc1cccc(c1)C(\C)=C\CN1CCCCC1
Show InChI InChI=1S/C16H23NO/c1-14(9-12-17-10-4-3-5-11-17)15-7-6-8-16(13-15)18-2/h6-9,13H,3-5,10-12H2,1-2H3/b14-9+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 91n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50357429
PNG
(CHEMBL1917702)
Show SMILES COc1ccc(cc1)C(\C)=C\CN(C)Cc1ccccc1
Show InChI InChI=1S/C19H23NO/c1-16(18-9-11-19(21-3)12-10-18)13-14-20(2)15-17-7-5-4-6-8-17/h4-13H,14-15H2,1-3H3/b16-13+
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 92n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357428
PNG
(CHEMBL1917701)
Show SMILES CN(C\C=C(/C)c1ccccc1)Cc1ccccc1
Show InChI InChI=1S/C18H21N/c1-16(18-11-7-4-8-12-18)13-14-19(2)15-17-9-5-3-6-10-17/h3-13H,14-15H2,1-2H3/b16-13+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 92n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50357428
PNG
(CHEMBL1917701)
Show SMILES CN(C\C=C(/C)c1ccccc1)Cc1ccccc1
Show InChI InChI=1S/C18H21N/c1-16(18-11-7-4-8-12-18)13-14-19(2)15-17-9-5-3-6-10-17/h3-13H,14-15H2,1-2H3/b16-13+
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 119n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50357431
PNG
(CHEMBL1917712)
Show SMILES COc1ccc(cc1)C(\C)=C\CN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H29NO/c1-19(22-8-10-23(25-2)11-9-22)12-15-24-16-13-21(14-17-24)18-20-6-4-3-5-7-20/h3-12,21H,13-18H2,1-2H3/b19-12+
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 149n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50357430
PNG
(CHEMBL1917711)
Show SMILES C\C(=C/CN1CCC(Cc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C22H27N/c1-19(22-10-6-3-7-11-22)12-15-23-16-13-21(14-17-23)18-20-8-4-2-5-9-20/h2-12,21H,13-18H2,1H3/b19-12+
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 152n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50357431
PNG
(CHEMBL1917712)
Show SMILES COc1ccc(cc1)C(\C)=C\CN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H29NO/c1-19(22-8-10-23(25-2)11-9-22)12-15-24-16-13-21(14-17-24)18-20-6-4-3-5-7-20/h3-12,21H,13-18H2,1-2H3/b19-12+
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 157n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50357430
PNG
(CHEMBL1917711)
Show SMILES C\C(=C/CN1CCC(Cc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C22H27N/c1-19(22-10-6-3-7-11-22)12-15-23-16-13-21(14-17-23)18-20-8-4-2-5-9-20/h2-12,21H,13-18H2,1H3/b19-12+
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 189n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50357429
PNG
(CHEMBL1917702)
Show SMILES COc1ccc(cc1)C(\C)=C\CN(C)Cc1ccccc1
Show InChI InChI=1S/C19H23NO/c1-16(18-9-11-19(21-3)12-10-18)13-14-20(2)15-17-7-5-4-6-8-17/h4-13H,14-15H2,1-3H3/b16-13+
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 197n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50357447
PNG
(CHEMBL1917713)
Show SMILES COc1cccc(c1)C(\C)=C\CN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H29NO/c1-19(22-9-6-10-23(18-22)25-2)11-14-24-15-12-21(13-16-24)17-20-7-4-3-5-8-20/h3-11,18,21H,12-17H2,1-2H3/b19-11+
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 214n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50357432
PNG
(CHEMBL1917703)
Show SMILES COc1cccc(c1)C(\C)=C\CN(C)Cc1ccccc1
Show InChI InChI=1S/C19H23NO/c1-16(18-10-7-11-19(14-18)21-3)12-13-20(2)15-17-8-5-4-6-9-17/h4-12,14H,13,15H2,1-3H3/b16-12+
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 301n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50357428
PNG
(CHEMBL1917701)
Show SMILES CN(C\C=C(/C)c1ccccc1)Cc1ccccc1
Show InChI InChI=1S/C18H21N/c1-16(18-11-7-4-8-12-18)13-14-19(2)15-17-9-5-3-6-10-17/h3-13H,14-15H2,1-2H3/b16-13+
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 438n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357442
PNG
(CHEMBL1917706)
Show SMILES C\C(=C/CN1CCCCC1)c1ccccc1
Show InChI InChI=1S/C15H21N/c1-14(15-8-4-2-5-9-15)10-13-16-11-6-3-7-12-16/h2,4-5,8-10H,3,6-7,11-13H2,1H3/b14-10+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 459n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357438
PNG
(CHEMBL1917699)
Show SMILES COc1ccc(cc1)C(\C)=C\CN(C)C
Show InChI InChI=1S/C13H19NO/c1-11(9-10-14(2)3)12-5-7-13(15-4)8-6-12/h5-9H,10H2,1-4H3/b11-9+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 806n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357451
PNG
(CHEMBL1917717)
Show SMILES COc1ccc(cc1)C(\C)=C\CN1CCOCC1
Show InChI InChI=1S/C15H21NO2/c1-13(7-8-16-9-11-18-12-10-16)14-3-5-15(17-2)6-4-14/h3-7H,8-12H2,1-2H3/b13-7+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357450
PNG
(CHEMBL1917716)
Show SMILES C\C(=C/CN1CCOCC1)c1ccccc1
Show InChI InChI=1S/C14H19NO/c1-13(14-5-3-2-4-6-14)7-8-15-9-11-16-12-10-15/h2-7H,8-12H2,1H3/b13-7+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357439
PNG
(CHEMBL1917700)
Show SMILES COc1cccc(c1)C(\C)=C\CN(C)C
Show InChI InChI=1S/C13H19NO/c1-11(8-9-14(2)3)12-6-5-7-13(10-12)15-4/h5-8,10H,9H2,1-4H3/b11-8+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50357452
PNG
(CHEMBL1917718)
Show SMILES COc1cccc(c1)C(\C)=C\CN1CCOCC1
Show InChI InChI=1S/C15H21NO2/c1-13(6-7-16-8-10-18-11-9-16)14-4-3-5-15(12-14)17-2/h3-6,12H,7-11H2,1-2H3/b13-6+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50022811
PNG
(CHEMBL1917698 | CHEMBL40791 | Dimethyl-(3-phenyl-b...)
Show SMILES CN(C)C\C=C(/C)c1ccccc1
Show InChI InChI=1S/C12H17N/c1-11(9-10-13(2)3)12-7-5-4-6-8-12/h4-9H,10H2,1-3H3/b11-9+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



University of Pavia

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting

Bioorg Med Chem 19: 6210-24 (2011)


Article DOI: 10.1016/j.bmc.2011.09.016
BindingDB Entry DOI: 10.7270/Q2VH5P7V
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%