| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50198061 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_788478 (CHEMBL1918281) |
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| Ki | 1.4±n/a nM |
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| Citation |  Rossi, D; Pedrali, A; Urbano, M; Gaggeri, R; Serra, M; Fernández, L; Fernández, M; Caballero, J; Ronsisvalle, S; Prezzavento, O; Schepmann, D; Wuensch, B; Peviani, M; Curti, D; Azzolina, O; Collina, S Identification of a potent and selectives¿? receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Bioorg Med Chem19:6210-24 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50198061 |
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| n/a |
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| Name | BDBM50198061 |
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| Synonyms: | (E)-N,N-dimethyl-3-(biphen-4-yl)but-2-en-1-ylamine | CHEMBL1917695 | CHEMBL448782 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21N |
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| Mol. Mass. | 251.366 |
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| SMILES | CN(C)C\C=C(/C)c1ccc(cc1)-c1ccccc1 |
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| Structure | 
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