Compile Data Set for Download or QSAR

Found 4892 hits with Last Name = 'urbano' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50130563 ((3R)-7-Hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphe...) Show SMILES CC(C)[C@@H](CN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1)NC(=O)[C@H]1Cc2ccc(O)cc2CN1 |r| Show InChI InChI=1S/C28H39N3O3/c1-18(2)26(30-27(34)25-13-20-8-9-24(33)12-21(20)15-29-25)17-31-11-10-28(4,19(3)16-31)22-6-5-7-23(32)14-22/h5-9,12,14,18-19,25-26,29,32-33H,10-11,13,15-17H2,1-4H3,(H,30,34)/t19-,25+,26+,28+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at kappa opioid receptor in guinea pig caudate assessed as inhibition of U69593-stimulated [35S]-GTP[gammaS] binding				Bioorg Med Chem Lett 24: 2021-32 (2014) Article DOI: 10.1016/j.bmcl.2014.03.040 BindingDB Entry DOI: 10.7270/Q2222WBX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50357453 (CHEMBL1917719) Show SMILES CC(CCN1CCCCC1)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H27N/c1-18(14-17-22-15-6-3-7-16-22)19-10-12-21(13-11-19)20-8-4-2-5-9-20/h2,4-5,8-13,18H,3,6-7,14-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50357441 (CHEMBL1917705) Show SMILES C\C(=C/CN1CCCCC1)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H25N/c1-18(14-17-22-15-6-3-7-16-22)19-10-12-21(13-11-19)20-8-4-2-5-9-20/h2,4-5,8-14H,3,6-7,15-17H2,1H3/b18-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50357440 (CHEMBL1917704) Show SMILES C\C(=C/CN1CCCCC1)c1ccc2ccccc2c1 Show InChI InChI=1S/C19H23N/c1-16(11-14-20-12-5-2-6-13-20)18-10-9-17-7-3-4-8-19(17)15-18/h3-4,7-11,15H,2,5-6,12-14H2,1H3/b16-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198054 ((3-biphenyl-4-yl-butyl)-dimethyl-amine | CHEMBL224...) Show SMILES CC(CCN(C)C)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C18H23N/c1-15(13-14-19(2)3)16-9-11-18(12-10-16)17-7-5-4-6-8-17/h4-12,15H,13-14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.02	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Bioorg Med Chem 15: 771-83 (2006) Article DOI: 10.1016/j.bmc.2006.10.048 BindingDB Entry DOI: 10.7270/Q29023F7
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50357430 (CHEMBL1917711) Show SMILES C\C(=C/CN1CCC(Cc2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C22H27N/c1-19(22-10-6-3-7-11-22)12-15-23-16-13-21(14-17-23)18-20-8-4-2-5-9-20/h2-12,21H,13-18H2,1H3/b19-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50350976 (CHEMBL1818341) Show SMILES CC(C)CNCc1ccc(cc1)-c1ccccc1S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C21H28N2O2S/c1-17(2)15-22-16-18-9-11-19(12-10-18)20-7-3-4-8-21(20)26(24,25)23-13-5-6-14-23/h3-4,7-12,17,22H,5-6,13-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of U69593-stimulated [35S]-GTP[gammaS] bindin...				Bioorg Med Chem Lett 24: 2021-32 (2014) Article DOI: 10.1016/j.bmcl.2014.03.040 BindingDB Entry DOI: 10.7270/Q2222WBX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310078 ((R/S)-1-(3-(6-Methoxynaphthalen-2-yl)butyl)piperid...) Show SMILES COc1ccc2cc(ccc2c1)C(C)CCN1CCCCC1 Show InChI InChI=1S/C20H27NO/c1-16(10-13-21-11-4-3-5-12-21)17-6-7-19-15-20(22-2)9-8-18(19)14-17/h6-9,14-16H,3-5,10-13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198061 ((E)-N,N-dimethyl-3-(biphen-4-yl)but-2-en-1-ylamine...) Show SMILES CN(C)C\C=C(/C)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C18H21N/c1-15(13-14-19(2)3)16-9-11-18(12-10-16)17-7-5-4-6-8-17/h4-13H,14H2,1-3H3/b15-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198061 ((E)-N,N-dimethyl-3-(biphen-4-yl)but-2-en-1-ylamine...) Show SMILES CN(C)C\C=C(/C)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C18H21N/c1-15(13-14-19(2)3)16-9-11-18(12-10-16)17-7-5-4-6-8-17/h4-13H,14H2,1-3H3/b15-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Bioorg Med Chem 15: 771-83 (2006) Article DOI: 10.1016/j.bmc.2006.10.048 BindingDB Entry DOI: 10.7270/Q29023F7
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50531908 (Btrx-335140 | CYM-53093 | US10676469, Compound 142...) Show SMILES CCc1cc(F)c2nc(N3CCC(CC3)NC3CCOCC3)c(-c3nc(C)no3)c(C)c2c1 Show InChI InChI=1S/C25H32FN5O2/c1-4-17-13-20-15(2)22(25-27-16(3)30-33-25)24(29-23(20)21(26)14-17)31-9-5-18(6-10-31)28-19-7-11-32-12-8-19/h13-14,18-19,28H,4-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human KOR				J Med Chem 62: 1761-1780 (2019) Article DOI: 10.1021/acs.jmedchem.8b01679 BindingDB Entry DOI: 10.7270/Q2CV4N6Q
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50012152 (CHEMBL3264441) Show SMILES CCOC(=O)C(CN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1)OC(=O)[C@H]1Cc2ccc(O)cc2CN1 |r| Show InChI InChI=1S/C28H36N2O6/c1-4-35-27(34)25(36-26(33)24-13-19-8-9-23(32)12-20(19)15-29-24)17-30-11-10-28(3,18(2)16-30)21-6-5-7-22(31)14-21/h5-9,12,14,18,24-25,29,31-32H,4,10-11,13,15-17H2,1-3H3/t18-,24+,25?,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from kappa opioid receptor (unknown origin) expressed in CHO cells membranes				Bioorg Med Chem Lett 24: 2021-32 (2014) Article DOI: 10.1016/j.bmcl.2014.03.040 BindingDB Entry DOI: 10.7270/Q2222WBX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198064 (CHEMBL224855 | N,N-dimethyl-3-(naphthalen-2-yl)but...) Show SMILES CC(CCN(C)C)c1ccc2ccccc2c1 Show InChI InChI=1S/C16H21N/c1-13(10-11-17(2)3)15-9-8-14-6-4-5-7-16(14)12-15/h4-9,12-13H,10-11H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Bioorg Med Chem 15: 771-83 (2006) Article DOI: 10.1016/j.bmc.2006.10.048 BindingDB Entry DOI: 10.7270/Q29023F7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50130563 ((3R)-7-Hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphe...) Show SMILES CC(C)[C@@H](CN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1)NC(=O)[C@H]1Cc2ccc(O)cc2CN1 |r| Show InChI InChI=1S/C28H39N3O3/c1-18(2)26(30-27(34)25-13-20-8-9-24(33)12-21(20)15-29-25)17-31-11-10-28(4,19(3)16-31)22-6-5-7-23(32)14-22/h5-9,12,14,18-19,25-26,29,32-33H,10-11,13,15-17H2,1-4H3,(H,30,34)/t19-,25+,26+,28+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at mu opioid receptor in guinea pig caudate assessed as inhibition of DAMGO-stimulated [35S]-GTP[gammaS] binding				Bioorg Med Chem Lett 24: 2021-32 (2014) Article DOI: 10.1016/j.bmcl.2014.03.040 BindingDB Entry DOI: 10.7270/Q2222WBX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198055 ((R/S)-3-(6-Methoxynaphthalen-2-yl)-N,N-dimethylbut...) Show SMILES COc1ccc2cc(ccc2c1)C(C)CCN(C)C Show InChI InChI=1S/C17H23NO/c1-13(9-10-18(2)3)14-5-6-16-12-17(19-4)8-7-15(16)11-14/h5-8,11-13H,9-10H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Bioorg Med Chem 15: 771-83 (2006) Article DOI: 10.1016/j.bmc.2006.10.048 BindingDB Entry DOI: 10.7270/Q29023F7
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310077 ((R/S)-N-Benzyl-3-(6-methoxynaphthalen-2-yl)-N-meth...) Show SMILES COc1ccc2cc(ccc2c1)C(C)CCN(C)Cc1ccccc1 Show InChI InChI=1S/C23H27NO/c1-18(13-14-24(2)17-19-7-5-4-6-8-19)20-9-10-22-16-23(25-3)12-11-21(22)15-20/h4-12,15-16,18H,13-14,17H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310074 ((R/S)-4-(benzyl(methyl)amino)-2-(biphenyl-4-yl)but...) Show SMILES CN(CCC(C)(O)c1ccc(cc1)-c1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C24H27NO/c1-24(26,17-18-25(2)19-20-9-5-3-6-10-20)23-15-13-22(14-16-23)21-11-7-4-8-12-21/h3-16,26H,17-19H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50198062 ((R/S)-N-Benzyl-3-(biphenyl-4-yl)-N-methylbutan-1-a...) Show SMILES CC(CCN(C)Cc1ccccc1)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C24H27N/c1-20(17-18-25(2)19-21-9-5-3-6-10-21)22-13-15-24(16-14-22)23-11-7-4-8-12-23/h3-16,20H,17-19H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50357431 (CHEMBL1917712) Show SMILES COc1ccc(cc1)C(\C)=C\CN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C23H29NO/c1-19(22-8-10-23(25-2)11-9-22)12-15-24-16-13-21(14-17-24)18-20-6-4-3-5-7-20/h3-12,21H,13-18H2,1-2H3/b19-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50198065 (4(E)-N-Benzyl-3-(biphenyl-4-yl)-N-methylbut-2-en-1...) Show SMILES CN(C\C=C(/C)c1ccc(cc1)-c1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C24H25N/c1-20(17-18-25(2)19-21-9-5-3-6-10-21)22-13-15-24(16-14-22)23-11-7-4-8-12-23/h3-17H,18-19H2,1-2H3/b20-17+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310076 ((E)-1-(3-(6-Methoxynaphthalen-2-yl)but-2-enyl)pipe...) Show SMILES COc1ccc2cc(ccc2c1)C(\C)=C\CN1CCCCC1 Show InChI InChI=1S/C20H25NO/c1-16(10-13-21-11-4-3-5-12-21)17-6-7-19-15-20(22-2)9-8-18(19)14-17/h6-10,14-15H,3-5,11-13H2,1-2H3/b16-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50357429 (CHEMBL1917702) Show SMILES COc1ccc(cc1)C(\C)=C\CN(C)Cc1ccccc1 Show InChI InChI=1S/C19H23NO/c1-16(18-9-11-19(21-3)12-10-18)13-14-20(2)15-17-7-5-4-6-8-17/h4-13H,14-15H2,1-3H3/b16-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198063 (CHEMBL387955 | N-benzyl-N-methyl-3-(naphthalen-2-y...) Show SMILES CC(CCN(C)Cc1ccccc1)c1ccc2ccccc2c1 Show InChI InChI=1S/C22H25N/c1-18(14-15-23(2)17-19-8-4-3-5-9-19)21-13-12-20-10-6-7-11-22(20)16-21/h3-13,16,18H,14-15,17H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Bioorg Med Chem 15: 771-83 (2006) Article DOI: 10.1016/j.bmc.2006.10.048 BindingDB Entry DOI: 10.7270/Q29023F7
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198062 ((R/S)-N-Benzyl-3-(biphenyl-4-yl)-N-methylbutan-1-a...) Show SMILES CC(CCN(C)Cc1ccccc1)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C24H27N/c1-20(17-18-25(2)19-21-9-5-3-6-10-21)22-13-15-24(16-14-22)23-11-7-4-8-12-23/h3-16,20H,17-19H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Bioorg Med Chem 15: 771-83 (2006) Article DOI: 10.1016/j.bmc.2006.10.048 BindingDB Entry DOI: 10.7270/Q29023F7
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310072 ((R/S)-4-(Benzyl(methyl)amino)-2-(6-methoxynaphthal...) Show SMILES COc1ccc2cc(ccc2c1)C(C)(O)CCN(C)Cc1ccccc1 Show InChI InChI=1S/C23H27NO2/c1-23(25,13-14-24(2)17-18-7-5-4-6-8-18)21-11-9-20-16-22(26-3)12-10-19(20)15-21/h4-12,15-16,25H,13-14,17H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.04	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198065 (4(E)-N-Benzyl-3-(biphenyl-4-yl)-N-methylbut-2-en-1...) Show SMILES CN(C\C=C(/C)c1ccc(cc1)-c1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C24H25N/c1-20(17-18-25(2)19-21-9-5-3-6-10-21)22-13-15-24(16-14-22)23-11-7-4-8-12-23/h3-17H,18-19H2,1-2H3/b20-17+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Bioorg Med Chem 15: 771-83 (2006) Article DOI: 10.1016/j.bmc.2006.10.048 BindingDB Entry DOI: 10.7270/Q29023F7
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198065 (4(E)-N-Benzyl-3-(biphenyl-4-yl)-N-methylbut-2-en-1...) Show SMILES CN(C\C=C(/C)c1ccc(cc1)-c1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C24H25N/c1-20(17-18-25(2)19-21-9-5-3-6-10-21)22-13-15-24(16-14-22)23-11-7-4-8-12-23/h3-17H,18-19H2,1-2H3/b20-17+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50012151 (CHEMBL3264440) Show SMILES C[C@H]1CN(CCCOC(=O)[C@H]2Cc3ccc(O)cc3CN2)CC[C@@]1(C)c1cccc(O)c1 |r| Show InChI InChI=1S/C26H34N2O4/c1-18-17-28(11-9-26(18,2)21-5-3-6-22(29)15-21)10-4-12-32-25(31)24-14-19-7-8-23(30)13-20(19)16-27-24/h3,5-8,13,15,18,24,27,29-30H,4,9-12,14,16-17H2,1-2H3/t18-,24+,26+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from mu opioid receptor (unknown origin) expressed in CHO cells membranes				Bioorg Med Chem Lett 24: 2021-32 (2014) Article DOI: 10.1016/j.bmcl.2014.03.040 BindingDB Entry DOI: 10.7270/Q2222WBX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50357446 (CHEMBL1917710) Show SMILES C\C(=C/CN1CCC(Cc2ccccc2)CC1)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C28H31N/c1-23(26-12-14-28(15-13-26)27-10-6-3-7-11-27)16-19-29-20-17-25(18-21-29)22-24-8-4-2-5-9-24/h2-16,25H,17-22H2,1H3/b23-16+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.02	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50357447 (CHEMBL1917713) Show SMILES COc1cccc(c1)C(\C)=C\CN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C23H29NO/c1-19(22-9-6-10-23(18-22)25-2)11-14-24-15-12-21(13-16-24)17-20-7-4-3-5-8-20/h3-11,18,21H,12-17H2,1-2H3/b19-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198058 ((E)-N-benzyl-N-methyl-3-(naphthalen-2-yl)but-2-en-...) Show SMILES CN(C\C=C(/C)c1ccc2ccccc2c1)Cc1ccccc1 Show InChI InChI=1S/C22H23N/c1-18(14-15-23(2)17-19-8-4-3-5-9-19)21-13-12-20-10-6-7-11-22(20)16-21/h3-14,16H,15,17H2,1-2H3/b18-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198058 ((E)-N-benzyl-N-methyl-3-(naphthalen-2-yl)but-2-en-...) Show SMILES CN(C\C=C(/C)c1ccc2ccccc2c1)Cc1ccccc1 Show InChI InChI=1S/C22H23N/c1-18(14-15-23(2)17-19-8-4-3-5-9-19)21-13-12-20-10-6-7-11-22(20)16-21/h3-14,16H,15,17H2,1-2H3/b18-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Bioorg Med Chem 15: 771-83 (2006) Article DOI: 10.1016/j.bmc.2006.10.048 BindingDB Entry DOI: 10.7270/Q29023F7
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50357448 (CHEMBL1917714) Show SMILES C\C(=C/CN1CCOCC1)c1ccc2ccccc2c1 Show InChI InChI=1S/C18H21NO/c1-15(8-9-19-10-12-20-13-11-19)17-7-6-16-4-2-3-5-18(16)14-17/h2-8,14H,9-13H2,1H3/b15-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50350976 (CHEMBL1818341) Show SMILES CC(C)CNCc1ccc(cc1)-c1ccccc1S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C21H28N2O2S/c1-17(2)15-22-16-18-9-11-19(12-10-18)20-7-3-4-8-21(20)26(24,25)23-13-5-6-14-23/h3-4,7-12,17,22H,5-6,13-16H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-stimulated [35S]-GTP[gammaS] binding				Bioorg Med Chem Lett 24: 2021-32 (2014) Article DOI: 10.1016/j.bmcl.2014.03.040 BindingDB Entry DOI: 10.7270/Q2222WBX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50357432 (CHEMBL1917703) Show SMILES COc1cccc(c1)C(\C)=C\CN(C)Cc1ccccc1 Show InChI InChI=1S/C19H23NO/c1-16(18-10-7-11-19(14-18)21-3)12-13-20(2)15-17-8-5-4-6-9-17/h4-12,14H,13,15H2,1-3H3/b16-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310073 ((R/S)-2-(6-Methoxynaphthalen-2-yl)-4-(piperidin-1-...) Show SMILES COc1ccc2cc(ccc2c1)C(C)(O)CCN1CCCCC1 Show InChI InChI=1S/C20H27NO2/c1-20(22,10-13-21-11-4-3-5-12-21)18-8-6-17-15-19(23-2)9-7-16(17)14-18/h6-9,14-15,22H,3-5,10-13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50357449 (CHEMBL1917715) Show SMILES C\C(=C/CN1CCOCC1)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H23NO/c1-17(11-12-21-13-15-22-16-14-21)18-7-9-20(10-8-18)19-5-3-2-4-6-19/h2-11H,12-16H2,1H3/b17-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50310075 ((E)-N-Benzyl-3-(6-methoxynaphthalen-2-yl)-N-methyl...) Show SMILES COc1ccc2cc(ccc2c1)C(\C)=C\CN(C)Cc1ccccc1 Show InChI InChI=1S/C23H25NO/c1-18(13-14-24(2)17-19-7-5-4-6-8-19)20-9-10-22-16-23(25-3)12-11-21(22)15-20/h4-13,15-16H,14,17H2,1-3H3/b18-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50357443 (CHEMBL1917707) Show SMILES COc1ccc(cc1)C(\C)=C\CN1CCCCC1 Show InChI InChI=1S/C16H23NO/c1-14(10-13-17-11-4-3-5-12-17)15-6-8-16(18-2)9-7-15/h6-10H,3-5,11-13H2,1-2H3/b14-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50198055 ((R/S)-3-(6-Methoxynaphthalen-2-yl)-N,N-dimethylbut...) Show SMILES COc1ccc2cc(ccc2c1)C(C)CCN(C)C Show InChI InChI=1S/C17H23NO/c1-13(9-10-18(2)3)14-5-6-16-12-17(19-4)8-7-15(16)11-14/h5-8,11-13H,9-10H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenate				Bioorg Med Chem 18: 1204-12 (2010) Article DOI: 10.1016/j.bmc.2009.12.039 BindingDB Entry DOI: 10.7270/Q2PN95S5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198067 ((R/S)-N,N-dimethyl-3-(6-hydroxy-naphthalen-2-yl)bu...) Show SMILES CC(CCN(C)C)c1ccc2cc(O)ccc2c1 Show InChI InChI=1S/C16H21NO/c1-12(8-9-17(2)3)13-4-5-15-11-16(18)7-6-14(15)10-13/h4-7,10-12,18H,8-9H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Bioorg Med Chem 15: 771-83 (2006) Article DOI: 10.1016/j.bmc.2006.10.048 BindingDB Entry DOI: 10.7270/Q29023F7
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198068 ((E)-N,N-dimethyl-3-(naphthalen-2-yl)but-2-en-1-ami...) Show SMILES CN(C)C\C=C(/C)c1ccc2ccccc2c1 Show InChI InChI=1S/C16H19N/c1-13(10-11-17(2)3)15-9-8-14-6-4-5-7-16(14)12-15/h4-10,12H,11H2,1-3H3/b13-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Bioorg Med Chem 15: 771-83 (2006) Article DOI: 10.1016/j.bmc.2006.10.048 BindingDB Entry DOI: 10.7270/Q29023F7
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198068 ((E)-N,N-dimethyl-3-(naphthalen-2-yl)but-2-en-1-ami...) Show SMILES CN(C)C\C=C(/C)c1ccc2ccccc2c1 Show InChI InChI=1S/C16H19N/c1-13(10-11-17(2)3)15-9-8-14-6-4-5-7-16(14)12-15/h4-10,12H,11H2,1-3H3/b13-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50248984 (CHEMBL473989 | N-Benzyl-3-[1-(4-fluorophenyl)-1H-i...) Show SMILES CN(CCCc1cn(-c2ccc(F)cc2)c2ccccc12)Cc1ccccc1 Show InChI InChI=1S/C25H25FN2/c1-27(18-20-8-3-2-4-9-20)17-7-10-21-19-28(23-15-13-22(26)14-16-23)25-12-6-5-11-24(21)25/h2-6,8-9,11-16,19H,7,10,17-18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H] (+)-pentazocine from sigma 1 receptor in rat liver homogenate				Eur J Med Chem 43: 2073-81 (2008) Article DOI: 10.1016/j.ejmech.2007.09.012 BindingDB Entry DOI: 10.7270/Q27D2TW8
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50264571 (CHEMBL523473 | N-(2,4-Dimethylbenzyl)-4-[1-(4-fluo...) Show SMILES CN(CCCCc1cn(-c2ccc(F)cc2)c2ccccc12)Cc1ccc(C)c(C)c1 Show InChI InChI=1S/C28H31FN2/c1-21-11-12-23(18-22(21)2)19-30(3)17-7-6-8-24-20-31(26-15-13-25(29)14-16-26)28-10-5-4-9-27(24)28/h4-5,9-16,18,20H,6-8,17,19H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H] (+)-pentazocine from sigma 1 receptor in rat liver homogenate				Eur J Med Chem 43: 2073-81 (2008) Article DOI: 10.1016/j.ejmech.2007.09.012 BindingDB Entry DOI: 10.7270/Q27D2TW8
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198066 ((E)-3-(6-Methoxynaphthalen-2-yl)-N,N-dimethylbut-2...) Show SMILES COc1ccc2cc(ccc2c1)C(\C)=C\CN(C)C Show InChI InChI=1S/C17H21NO/c1-13(9-10-18(2)3)14-5-6-16-12-17(19-4)8-7-15(16)11-14/h5-9,11-12H,10H2,1-4H3/b13-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Bioorg Med Chem 15: 771-83 (2006) Article DOI: 10.1016/j.bmc.2006.10.048 BindingDB Entry DOI: 10.7270/Q29023F7
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50357445 (CHEMBL1917709) Show SMILES C\C(=C/CN1CCC(Cc2ccccc2)CC1)c1ccc2ccccc2c1 Show InChI InChI=1S/C26H29N/c1-21(25-12-11-24-9-5-6-10-26(24)20-25)13-16-27-17-14-23(15-18-27)19-22-7-3-2-4-8-22/h2-13,20,23H,14-19H2,1H3/b21-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				Bioorg Med Chem 19: 6210-24 (2011) Article DOI: 10.1016/j.bmc.2011.09.016 BindingDB Entry DOI: 10.7270/Q2VH5P7V
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50012151 (CHEMBL3264440) Show SMILES C[C@H]1CN(CCCOC(=O)[C@H]2Cc3ccc(O)cc3CN2)CC[C@@]1(C)c1cccc(O)c1 |r| Show InChI InChI=1S/C26H34N2O4/c1-18-17-28(11-9-26(18,2)21-5-3-6-22(29)15-21)10-4-12-32-25(31)24-14-19-7-8-23(30)13-20(19)16-27-24/h3,5-8,13,15,18,24,27,29-30H,4,9-12,14,16-17H2,1-2H3/t18-,24+,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from kappa opioid receptor (unknown origin) expressed in CHO cells membranes				Bioorg Med Chem Lett 24: 2021-32 (2014) Article DOI: 10.1016/j.bmcl.2014.03.040 BindingDB Entry DOI: 10.7270/Q2222WBX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50198057 ((R/S)-4-(dimethylamino)-2-(naphthalen-2-yl)butan-2...) Show SMILES CN(C)CCCC(C)(O)c1ccc2ccccc2c1 Show InChI InChI=1S/C17H23NO/c1-17(19,11-6-12-18(2)3)16-10-9-14-7-4-5-8-15(14)13-16/h4-5,7-10,13,19H,6,11-12H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pavia Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Bioorg Med Chem 15: 771-83 (2006) Article DOI: 10.1016/j.bmc.2006.10.048 BindingDB Entry DOI: 10.7270/Q29023F7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50012152 (CHEMBL3264441) Show SMILES CCOC(=O)C(CN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1)OC(=O)[C@H]1Cc2ccc(O)cc2CN1 |r| Show InChI InChI=1S/C28H36N2O6/c1-4-35-27(34)25(36-26(33)24-13-19-8-9-23(32)12-20(19)15-29-24)17-30-11-10-28(3,18(2)16-30)21-6-5-7-22(31)14-21/h5-9,12,14,18,24-25,29,31-32H,4,10-11,13,15-17H2,1-3H3/t18-,24+,25?,28+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from mu opioid receptor (unknown origin) expressed in CHO cells membranes				Bioorg Med Chem Lett 24: 2021-32 (2014) Article DOI: 10.1016/j.bmcl.2014.03.040 BindingDB Entry DOI: 10.7270/Q2222WBX
					More data for this Ligand-Target Pair

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