Affinity Data by PubMed id=22490010

PubMed code 22490010

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vitamin D3 receptor (Rattus norvegicus)	BDBM50388439 (CHEMBL2059272) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Displacement of [3H]-1alpha,25(OH)2D3 from recombinant rat VDR after overnight incubation by scintillation counting				J Med Chem 55: 4352-66 (2012) Article DOI: 10.1021/jm300187x BindingDB Entry DOI: 10.7270/Q2PK0H71
University of Wisconsin-Madison Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Rattus norvegicus)	BDBM50388440 (CHEMBL2059269) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Displacement of [3H]-1alpha,25(OH)2D3 from recombinant rat VDR after overnight incubation by scintillation counting				J Med Chem 55: 4352-66 (2012) Article DOI: 10.1021/jm300187x BindingDB Entry DOI: 10.7270/Q2PK0H71
University of Wisconsin-Madison Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Rattus norvegicus)	BDBM50388438 (CHEMBL2059271) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Displacement of [3H]-1alpha,25(OH)2D3 from recombinant rat VDR after overnight incubation by scintillation counting				J Med Chem 55: 4352-66 (2012) Article DOI: 10.1021/jm300187x BindingDB Entry DOI: 10.7270/Q2PK0H71
University of Wisconsin-Madison Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Rattus norvegicus)	BDBM50388434 (CHEMBL605525) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Displacement of [3H]-1alpha,25(OH)2D3 from recombinant rat VDR after overnight incubation by scintillation counting				J Med Chem 55: 4352-66 (2012) Article DOI: 10.1021/jm300187x BindingDB Entry DOI: 10.7270/Q2PK0H71
University of Wisconsin-Madison Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Vitamin D3 receptor (Rattus norvegicus)	BDBM50388436 (CHEMBL2059268) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Displacement of [3H]-1alpha,25(OH)2D3 from recombinant rat VDR after overnight incubation by scintillation counting				J Med Chem 55: 4352-66 (2012) Article DOI: 10.1021/jm300187x BindingDB Entry DOI: 10.7270/Q2PK0H71
University of Wisconsin-Madison Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Rattus norvegicus)	BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Displacement of [3H]-1alpha,25(OH)2D3 from recombinant rat VDR after overnight incubation by scintillation counting				J Med Chem 55: 4352-66 (2012) Article DOI: 10.1021/jm300187x BindingDB Entry DOI: 10.7270/Q2PK0H71
University of Wisconsin-Madison Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Vitamin D3 receptor (Rattus norvegicus)	BDBM50388435 (CHEMBL2059267) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Displacement of [3H]-1alpha,25(OH)2D3 from recombinant rat VDR after overnight incubation by scintillation counting				J Med Chem 55: 4352-66 (2012) Article DOI: 10.1021/jm300187x BindingDB Entry DOI: 10.7270/Q2PK0H71
University of Wisconsin-Madison Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Rattus norvegicus)	BDBM50388437 (CHEMBL2059270) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Displacement of [3H]-1alpha,25(OH)2D3 from recombinant rat VDR after overnight incubation by scintillation counting				J Med Chem 55: 4352-66 (2012) Article DOI: 10.1021/jm300187x BindingDB Entry DOI: 10.7270/Q2PK0H71
University of Wisconsin-Madison Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%