Found 3 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50386178
(CHEMBL1800346 | ONO-1714)Show SMILES C[C@H]1CC(N)=N[C@@H]2[C@H](Cl)[C@H]12 |r,c:4| Show InChI InChI=1S/C7H11ClN2/c1-3-2-4(9)10-7-5(3)6(7)8/h3,5-7H,2H2,1H3,(H2,9,10)/t3-,5?,6+,7-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Cajal (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human iNOS |
Eur J Med Chem 54: 439-46 (2012)
Article DOI: 10.1016/j.ejmech.2012.05.031 BindingDB Entry DOI: 10.7270/Q2NC6280 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Rattus norvegicus) | BDBM50386178
(CHEMBL1800346 | ONO-1714)Show SMILES C[C@H]1CC(N)=N[C@@H]2[C@H](Cl)[C@H]12 |r,c:4| Show InChI InChI=1S/C7H11ClN2/c1-3-2-4(9)10-7-5(3)6(7)8/h3,5-7H,2H2,1H3,(H2,9,10)/t3-,5?,6+,7-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Cajal (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of rat iNOS |
Eur J Med Chem 54: 439-46 (2012)
Article DOI: 10.1016/j.ejmech.2012.05.031 BindingDB Entry DOI: 10.7270/Q2NC6280 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Mus musculus (mouse)) | BDBM50386178
(CHEMBL1800346 | ONO-1714)Show SMILES C[C@H]1CC(N)=N[C@@H]2[C@H](Cl)[C@H]12 |r,c:4| Show InChI InChI=1S/C7H11ClN2/c1-3-2-4(9)10-7-5(3)6(7)8/h3,5-7H,2H2,1H3,(H2,9,10)/t3-,5?,6+,7-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Cajal (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant iNOS activity assessed as conversion of [14C]-L-arginine to [14C]-L-citrulline by liquid scintillation counting |
Eur J Med Chem 54: 439-46 (2012)
Article DOI: 10.1016/j.ejmech.2012.05.031 BindingDB Entry DOI: 10.7270/Q2NC6280 |
More data for this Ligand-Target Pair | |