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PubMed code 22901392

Compile data set for download or QSAR
Found 27 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396827
PNG
(CHEMBL1712297)
Show SMILES ONC(=O)CN1C(=O)C2(OCCO2)c2cc(Br)ccc12
Show InChI InChI=1S/C12H11BrN2O5/c13-7-1-2-9-8(5-7)12(19-3-4-20-12)11(17)15(9)6-10(16)14-18/h1-2,5,18H,3-4,6H2,(H,14,16)
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 2.79E+3n/an/an/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate by Dixon method

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
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 3.73E+3n/an/an/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate by Dixon method

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396827
PNG
(CHEMBL1712297)
Show SMILES ONC(=O)CN1C(=O)C2(OCCO2)c2cc(Br)ccc12
Show InChI InChI=1S/C12H11BrN2O5/c13-7-1-2-9-8(5-7)12(19-3-4-20-12)11(17)15(9)6-10(16)14-18/h1-2,5,18H,3-4,6H2,(H,14,16)
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n/an/a 3.70E+3n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
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n/an/a 8.90E+3n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50134396
PNG
(1-Allyl-3-(2,4,6-trioxo-tetrahydro-pyrimidin-5-yli...)
Show SMILES [#6]=[#6]-[#6]-[#7]-[#6](=S)-[#7]\[#6]=[#6]-1\[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]-1=O
Show InChI InChI=1S/C9H10N4O3S/c1-2-3-10-9(17)11-4-5-6(14)12-8(16)13-7(5)15/h2,4H,1,3H2,(H2,10,11,17)(H2,12,13,14,15,16)
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n/an/a 6.59E+4n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396826
PNG
(CHEMBL2170114)
Show SMILES NC(=O)c1ccccc1NC(=O)c1ccccc1C(O)=O
Show InChI InChI=1S/C15H12N2O4/c16-13(18)11-7-3-4-8-12(11)17-14(19)9-5-1-2-6-10(9)15(20)21/h1-8H,(H2,16,18)(H,17,19)(H,20,21)
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n/an/a 6.63E+4n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396825
PNG
(CHEMBL2170104)
Show SMILES COc1cc(\C=C2\C(=O)NC(=O)N(Cc3ccc(F)cc3)C2=O)cc(OC)c1O
Show InChI InChI=1S/C20H17FN2O6/c1-28-15-8-12(9-16(29-2)17(15)24)7-14-18(25)22-20(27)23(19(14)26)10-11-3-5-13(21)6-4-11/h3-9,24H,10H2,1-2H3,(H,22,25,27)/b14-7-
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n/an/a 7.89E+4n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM47291
PNG
(3-hydroxy-N-[(5Z)-4-keto-5-(2-ketoindolin-3-yliden...)
Show SMILES Oc1cccc(c1)C(=O)NN1C(=S)S\C(C1=O)=C1/C(=O)Nc2ccccc12
Show InChI InChI=1S/C18H11N3O4S2/c22-10-5-3-4-9(8-10)15(23)20-21-17(25)14(27-18(21)26)13-11-6-1-2-7-12(11)19-16(13)24/h1-8,22H,(H,19,24)(H,20,23)/b14-13-
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n/an/a 1.70E+5n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396824
PNG
(CHEMBL2170108)
Show SMILES OC(=O)COc1ccc(\C=N\n2c(COc3ccccc3)nc3ccccc3c2=O)cc1
Show InChI InChI=1S/C24H19N3O5/c28-23(29)16-32-19-12-10-17(11-13-19)14-25-27-22(15-31-18-6-2-1-3-7-18)26-21-9-5-4-8-20(21)24(27)30/h1-14H,15-16H2,(H,28,29)/b25-14+
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n/an/a 1.88E+5n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396823
PNG
(CHEMBL2170107)
Show SMILES Nc1nc2n(cnc2c(=O)[nH]1)S(=O)(=O)c1cccc(c1)C(O)=O
Show InChI InChI=1S/C12H9N5O5S/c13-12-15-9-8(10(18)16-12)14-5-17(9)23(21,22)7-3-1-2-6(4-7)11(19)20/h1-5H,(H,19,20)(H3,13,15,16,18)
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n/an/a 2.02E+5n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM53958
PNG
(CHEMBL1319666 | MLS000717879 | N-[[2-(4-bromanylph...)
Show SMILES CC(=O)NC(=S)NNC(=O)COc1ccc(Br)cc1
Show InChI InChI=1S/C11H12BrN3O3S/c1-7(16)13-11(19)15-14-10(17)6-18-9-4-2-8(12)3-5-9/h2-5H,6H2,1H3,(H,14,17)(H2,13,15,16,19)
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n/an/a 2.27E+5n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396836
PNG
(CHEMBL2170110)
Show SMILES CCOC(=O)C(N)=NNS(=O)(=O)c1ccc(C)cc1 |w:7.7|
Show InChI InChI=1S/C11H15N3O4S/c1-3-18-11(15)10(12)13-14-19(16,17)9-6-4-8(2)5-7-9/h4-7,14H,3H2,1-2H3,(H2,12,13)
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n/an/a 3.21E+5n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396835
PNG
(CHEMBL2170102)
Show SMILES NNC(=O)c1nnn(c1N)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C10H9F3N6O/c11-10(12,13)5-2-1-3-6(4-5)19-8(14)7(17-18-19)9(20)16-15/h1-4H,14-15H2,(H,16,20)
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n/an/a 3.23E+5n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396834
PNG
(CHEMBL2170100)
Show SMILES Nn1c(COc2ccccc2)n[nH]c1=S
Show InChI InChI=1S/C9H10N4OS/c10-13-8(11-12-9(13)15)6-14-7-4-2-1-3-5-7/h1-5H,6,10H2,(H,12,15)
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n/an/a 4.24E+5n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396833
PNG
(CHEMBL2170105)
Show SMILES NNC(=O)C(\NC(=O)c1ccc(Br)cc1)=C\c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C16H13BrN4O4/c17-12-5-3-11(4-6-12)15(22)19-14(16(23)20-18)9-10-1-7-13(8-2-10)21(24)25/h1-9H,18H2,(H,19,22)(H,20,23)/b14-9-
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n/an/a 4.38E+5n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM53888
PNG
(CHEMBL1505807 | MLS000685523 | N'-(1,1-dioxido...)
Show SMILES Cc1ccc(c(C)c1)S(=O)(=O)NN=C1NS(=O)(=O)c2ccccc12 |w:12.12|
Show InChI InChI=1S/C15H15N3O4S2/c1-10-7-8-13(11(2)9-10)24(21,22)18-16-15-12-5-3-4-6-14(12)23(19,20)17-15/h3-9,18H,1-2H3,(H,16,17)
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n/an/a 8.28E+5n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396838
PNG
(CHEMBL1935518)
Show SMILES NC(=S)NNC(=O)c1ccccc1C(O)=O
Show InChI InChI=1S/C9H9N3O3S/c10-9(16)12-11-7(13)5-3-1-2-4-6(5)8(14)15/h1-4H,(H,11,13)(H,14,15)(H3,10,12,16)
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n/an/a>1.00E+6n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM53913
PNG
(2,4,5,6(1H,3H)-pyrimidinetetrone 5-({2-hydroxy-5-n...)
Show SMILES Oc1ccc(cc1[NH+]=N[c-]1c(=O)[nH]c(=O)[nH]c1=O)[N+]([O-])=O |w:7.7|
Show InChI InChI=1S/C10H6N5O6/c16-6-2-1-4(15(20)21)3-5(6)13-14-7-8(17)11-10(19)12-9(7)18/h1-3,16H,(H2,11,12,17,18,19)/q-1/p+1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396840
PNG
(CHEMBL2170103)
Show SMILES CC(=NN1C(=O)c2ccccc2C1=O)c1cccc(c1)[N+]([O-])=O |w:2.2|
Show InChI InChI=1S/C16H11N3O4/c1-10(11-5-4-6-12(9-11)19(22)23)17-18-15(20)13-7-2-3-8-14(13)16(18)21/h2-9H,1H3
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n/an/a>1.00E+6n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396839
PNG
(CHEMBL2170106)
Show SMILES Cc1nc[nH]c1C=NNC(N)=S |w:6.6|
Show InChI InChI=1S/C6H9N5S/c1-4-5(9-3-8-4)2-10-11-6(7)12/h2-3H,1H3,(H,8,9)(H3,7,11,12)
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n/an/a>1.00E+6n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396841
PNG
(CHEMBL2170101)
Show SMILES NC(Cc1ccccc1)C(=O)NCCO
Show InChI InChI=1S/C11H16N2O2/c12-10(11(15)13-6-7-14)8-9-4-2-1-3-5-9/h1-5,10,14H,6-8,12H2,(H,13,15)
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n/an/a>1.00E+6n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396843
PNG
(CHEMBL1518403)
Show SMILES [#8]-[#6](=O)-c1cccc(-[#7]\[#7]=[#6]-2/[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]-2=O)c1
Show InChI InChI=1S/C11H8N4O5/c16-8-7(9(17)13-11(20)12-8)15-14-6-3-1-2-5(4-6)10(18)19/h1-4,14H,(H,18,19)(H2,12,13,16,17,20)
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n/an/a>1.00E+6n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396830
PNG
(CHEMBL2170111)
Show SMILES Nn1c(n[nH]c1=S)C(O)c1ccccc1
Show InChI InChI=1S/C9H10N4OS/c10-13-8(11-12-9(13)15)7(14)6-4-2-1-3-5-6/h1-5,7,14H,10H2,(H,12,15)
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n/an/a>1.00E+6n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396844
PNG
(CHEMBL2170113)
Show SMILES CC(=O)[C-](N=[NH+]c1cc(ccc1O)[N+]([O-])=O)C(N)=O |w:5.5|
Show InChI InChI=1S/C10H9N4O5/c1-5(15)9(10(11)17)13-12-7-4-6(14(18)19)2-3-8(7)16/h2-4,16H,1H3,(H2,11,17)/q-1/p+1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396842
PNG
(CHEMBL2170115)
Show SMILES CC[C@H](N)[C@H](O)c1ccc(OC)cc1 |r|
Show InChI InChI=1S/C11H17NO2/c1-3-10(12)11(13)8-4-6-9(14-2)7-5-8/h4-7,10-11,13H,3,12H2,1-2H3/t10-,11+/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396831
PNG
(CHEMBL2170109)
Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cccc1C=C1C(=O)NN(C1=O)c1ccc(Cl)cc1 |w:15.16|
Show InChI InChI=1S/C20H15ClN4O4S/c21-13-3-5-15(6-4-13)25-20(27)18(19(26)23-25)12-16-2-1-11-24(16)14-7-9-17(10-8-14)30(22,28)29/h1-12H,(H,23,26)(H2,22,28,29)
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PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50396829
PNG
(CHEMBL2170112)
Show SMILES Cc1cc([CH-]\N=[NH+]\c2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)c(C)n1-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C19H17N6O6S/c1-12-9-14(13(2)23(12)15-3-6-17(7-4-15)32(20,30)31)11-21-22-18-8-5-16(24(26)27)10-19(18)25(28)29/h3-11H,1-2H3,(H2,20,30,31)/q-1/p+1/b22-21+
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n/an/a>1.00E+6n/an/an/an/an/an/a



Shandong Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsome aminopeptidase using L-Leu-p-nitroanilide as substrate after 30 mins

Bioorg Med Chem Lett 22: 5863-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.086
BindingDB Entry DOI: 10.7270/Q2VD70KS
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%