Affinity Data by PubMed id=23123728

PubMed code 23123728

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50392587 (CHEMBL1230023) Show SMILES CCC[C@H]1COc2ccsc2C(N)=N1 \|r,c:13\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of wild type human iNOS expressed in Escherichia coli BL21(DE3) using L-Arg as substrate incubated for 1 hr prior to L-Arg addition				Eur J Med Chem 58: 117-27 (2012) Article DOI: 10.1016/j.ejmech.2012.10.010 BindingDB Entry DOI: 10.7270/Q29024XX
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50392587 (CHEMBL1230023) Show SMILES CCC[C@H]1COc2ccsc2C(N)=N1 \|r,c:13\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of wild type human eNOS using L-Arg as substrate incubated for 1 hr prior to L-Arg addition				Eur J Med Chem 58: 117-27 (2012) Article DOI: 10.1016/j.ejmech.2012.10.010 BindingDB Entry DOI: 10.7270/Q29024XX
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50148162 (4-(4-Methyl-pyridin-2-ylamino)-piperidine-1-carbox...) Show SMILES CCOC(=O)N1CCC(CC1)Nc1cc(C)ccn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of wild type human iNOS expressed in Escherichia coli BL21(DE3) using L-Arg as substrate incubated for 1 hr prior to L-Arg addition				Eur J Med Chem 58: 117-27 (2012) Article DOI: 10.1016/j.ejmech.2012.10.010 BindingDB Entry DOI: 10.7270/Q29024XX
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50148162 (4-(4-Methyl-pyridin-2-ylamino)-piperidine-1-carbox...) Show SMILES CCOC(=O)N1CCC(CC1)Nc1cc(C)ccn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of wild type human eNOS using L-Arg as substrate incubated for 1 hr prior to L-Arg addition				Eur J Med Chem 58: 117-27 (2012) Article DOI: 10.1016/j.ejmech.2012.10.010 BindingDB Entry DOI: 10.7270/Q29024XX
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%