Affinity Data by PubMed id=23167494

PubMed code 23167494

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50400180 (2,3‐dihydroxy‐6‐[(4‐ isopr...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Mcl-1 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50400180 (2,3‐dihydroxy‐6‐[(4‐ isopr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Bcl-2 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50400178 (2,3‐dihydroxy‐6‐[(4‐ methy...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Mcl-1 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50400178 (2,3‐dihydroxy‐6‐[(4‐ methy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Bcl-2 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50400179 (2,3‐dihydroxy‐6‐(phenylsulfanyl)...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Mcl-1 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50400177 (CHEMBL2180317) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Mcl-1 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50400179 (2,3‐dihydroxy‐6‐(phenylsulfanyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Bcl-2 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50400177 (CHEMBL2180317) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Bcl-2 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50400181 (6‐bromo‐2,3‐dihydroxyanthracene&...) Show SMILES Oc1cc2C(=O)c3ccc(Br)cc3C(=O)c2cc1O Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Mcl-1 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50400181 (6‐bromo‐2,3‐dihydroxyanthracene&...) Show SMILES Oc1cc2C(=O)c3ccc(Br)cc3C(=O)c2cc1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Bcl-2 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50400184 (CHEMBL192032) Show SMILES Oc1cc2C(=O)c3ccccc3C(=O)c2c(O)c1O Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Mcl-1 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50400182 (2,3‐dihydroxyanthracene‐9,10‐dio...) Show SMILES Oc1cc2C(=O)c3ccccc3C(=O)c2cc1O Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	312	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Mcl-1 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50400182 (2,3‐dihydroxyanthracene‐9,10‐dio...) Show SMILES Oc1cc2C(=O)c3ccccc3C(=O)c2cc1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Bcl-2 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50400184 (CHEMBL192032) Show SMILES Oc1cc2C(=O)c3ccccc3C(=O)c2c(O)c1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	583	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Bcl-2 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50206434 (1,2-Anthraquinonediol \| 1,2-dihydroxy-9,10-anthraq...) Show SMILES Oc1ccc2C(=O)c3ccccc3C(=O)c2c1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Bcl-2 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50206434 (1,2-Anthraquinonediol \| 1,2-dihydroxy-9,10-anthraq...) Show SMILES Oc1ccc2C(=O)c3ccccc3C(=O)c2c1O Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Mcl-1 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50400183 (Purpuro (Ligand 1) \| XANTHOPURPURIN) Show SMILES Oc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Bcl-2 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50400183 (Purpuro (Ligand 1) \| XANTHOPURPURIN) Show SMILES Oc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	2.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to Mcl-1 after 30 mins by florescence polarization assay				J Med Chem 55: 10735-41 (2012) Article DOI: 10.1021/jm301504b BindingDB Entry DOI: 10.7270/Q26Q1ZCM
Dalian University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%