BindingDB logo
myBDB logout

PubMed code 23182216

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Growth factor receptor-bound protein 2


(Homo sapiens (Human))
BDBM50436051
PNG
(CHEMBL2396935)
Show SMILES CC1(C)N=C(N)N=C(N)N1c1cccc(\C=C\C=Cc2cccc(c2)[N+]([O-])=O)c1 |w:17.17,t:3,6|
Show InChI InChI=1S/C21H22N6O2/c1-21(2)25-19(22)24-20(23)26(21)17-11-5-9-15(13-17)7-3-4-8-16-10-6-12-18(14-16)27(28)29/h3-14H,1-2H3,(H4,22,23,24,25)/b7-3+,8-4?
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.20E+5n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Competitive inhibition of GST-tagged Grb2 SH3C domain (unknown origin)-Gab2 interaction incubated 2 hrs prior to biotinylated Gab2b peptide addition ...


Bioorg Med Chem 21: 4027-33 (2013)


Article DOI: 10.1016/j.bmc.2012.10.023
BindingDB Entry DOI: 10.7270/Q2M32X4Z
More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Homo sapiens (Human))
BDBM50436052
PNG
(CHEMBL2396934)
Show SMILES CC1(C)N=C(N)N=C(N)N1c1cccc(CCCCc2cccc(N)c2)c1 |t:3,6|
Show InChI InChI=1S/C21H28N6/c1-21(2)26-19(23)25-20(24)27(21)18-12-6-10-16(14-18)8-4-3-7-15-9-5-11-17(22)13-15/h5-6,9-14H,3-4,7-8,22H2,1-2H3,(H4,23,24,25,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.70E+6n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Competitive inhibition of GST-tagged Grb2 SH3C domain (unknown origin)-Gab2 interaction incubated 2 hrs prior to biotinylated Gab2b peptide addition ...


Bioorg Med Chem 21: 4027-33 (2013)


Article DOI: 10.1016/j.bmc.2012.10.023
BindingDB Entry DOI: 10.7270/Q2M32X4Z
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%