BindingDB logo
myBDB logout

PubMed code 23214511

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50424227
PNG
(CHEMBL2314112)
Show SMILES CCCCCCNC(=O)Oc1cccc(c1)C1=NCCO1 |t:17|
Show InChI InChI=1S/C16H22N2O3/c1-2-3-4-5-9-18-16(19)21-14-8-6-7-13(12-14)15-17-10-11-20-15/h6-8,12H,2-5,9-11H2,1H3,(H,18,19)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.550n/an/an/an/an/an/a



Centre for Addiction and Mental Health

Curated by ChEMBL


Assay Description
Inhibition of FAAH-mediated [3H]anandamide hydrolysis in rat brain homogenate assessed as [3H]ethanolamine production incubated for 90 mins prior to ...


J Med Chem 56: 201-9 (2013)


Article DOI: 10.1021/jm301492y
BindingDB Entry DOI: 10.7270/Q2XD130R
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50424227
PNG
(CHEMBL2314112)
Show SMILES CCCCCCNC(=O)Oc1cccc(c1)C1=NCCO1 |t:17|
Show InChI InChI=1S/C16H22N2O3/c1-2-3-4-5-9-18-16(19)21-14-8-6-7-13(12-14)15-17-10-11-20-15/h6-8,12H,2-5,9-11H2,1H3,(H,18,19)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20n/an/an/an/an/an/a



Centre for Addiction and Mental Health

Curated by ChEMBL


Assay Description
Inhibition of FAAH-mediated [3H]anandamide hydrolysis in rat brain homogenate assessed as [3H]ethanolamine production incubated for 45 mins prior to ...


J Med Chem 56: 201-9 (2013)


Article DOI: 10.1021/jm301492y
BindingDB Entry DOI: 10.7270/Q2XD130R
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM97458
PNG
(FAAH Inhibitor, 2g)
Show SMILES Oc1ccc(OC(=O)NC2CCCCC2)cc1-c1ccccc1
Show InChI InChI=1S/C19H21NO3/c21-18-12-11-16(13-17(18)14-7-3-1-4-8-14)23-19(22)20-15-9-5-2-6-10-15/h1,3-4,7-8,11-13,15,21H,2,5-6,9-10H2,(H,20,22)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
MCE
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.90n/an/an/an/an/an/a



Centre for Addiction and Mental Health

Curated by ChEMBL


Assay Description
Inhibition of FAAH-mediated [3H]anandamide hydrolysis in rat brain homogenate assessed as [3H]ethanolamine production incubated for 90 mins prior to ...


J Med Chem 56: 201-9 (2013)


Article DOI: 10.1021/jm301492y
BindingDB Entry DOI: 10.7270/Q2XD130R
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM97458
PNG
(FAAH Inhibitor, 2g)
Show SMILES Oc1ccc(OC(=O)NC2CCCCC2)cc1-c1ccccc1
Show InChI InChI=1S/C19H21NO3/c21-18-12-11-16(13-17(18)14-7-3-1-4-8-14)23-19(22)20-15-9-5-2-6-10-15/h1,3-4,7-8,11-13,15,21H,2,5-6,9-10H2,(H,20,22)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
MCE
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.40n/an/an/an/an/an/a



Centre for Addiction and Mental Health

Curated by ChEMBL


Assay Description
Inhibition of FAAH-mediated [3H]anandamide hydrolysis in rat brain homogenate assessed as [3H]ethanolamine production incubated for 45 mins prior to ...


J Med Chem 56: 201-9 (2013)


Article DOI: 10.1021/jm301492y
BindingDB Entry DOI: 10.7270/Q2XD130R
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%